Abstracts tagged "Citrullin-Specific T cell lines"

Abstract Number: 1949 • 2015 ACR/ARHP Annual Meeting
Generation and Immunophenotyping of Citrullin-Specific T Cell Lines from Peripheral Blood and Synovial Fluid of ACPA+ RA Patients
Muhammad Sohel Mia¹, Christina Gerstner¹, Daniel Ramsköld¹, Jessica Herrath², Anatoly Dubnovitsky^1,3, Marline Marline⁴, Annika van Vollenhoven¹, Qiaolin Deng⁴, Adnane Achour³ and Vivianne Malmström⁵, ¹Department of Medicine, Rheumatology Unit, Karolinska University Hospital, Solna, Stockholm, Sweden, ²Department of Medicine,, Rheumatology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden, ³Department of Medicine, Science for Life Laboraories, Karolinska Institute, Stockholm, Sweden, ⁴Cell and Molecular Biology Department, Ludwig Institute for Cancer Research, Karolinska Institute, Solna, Stockholm, Sweden, ⁵Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Citrulline autoimmunity is a characteristic of ACPA+ Rheumatoid Arthritis (RA). Many autoantigens have been implicated even within patients of the same HLA such as…