Abstract Number: 1146 • 2015 ACR/ARHP Annual Meeting
Deficiency of TLR2 and TLR4 Impairs Autophagic Flux in Chondrocytes
Background/Purpose: We have previously demonstrated that chondrocyte deficient in both TLR2 and TLR4 almost completely abolished pro-catabolic responses to rHMGB1 and LMW-HA, which are known…