Abstracts tagged "Chondrocalcinosis"

Abstract Number: 347 • 2019 ACR/ARP Annual Meeting
Patterns and Clinico-Radiological Correlates of Symptomatic Atlantoaxial Joint Involvement in Patients with Calcium Pyrophosphate Deposition Disease
Joana Silva-Dinis¹, Catarina Tenazinha ², Nikita Khmelinskii ², Vítor Teixeira ², Pedro Ávila-Ribeiro ¹, João Eurico Fonseca ¹ and José-Carlos Romeu ², ¹Rheumatology and Bone Diseases Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Unidade de Investigação em Reumatologia, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa; Centro Académico de Medicina de Lisboa; Lisbon, Portugal., Lisbon, Portugal, ²Rheumatology and Bone Diseases Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; Lisbon, Portugal., Lisbon, Portugal
Background/Purpose: Atlantoaxial joint involvement in calcium pyrophosphate deposition disease (CPPD) may present as crowned dens syndrome (CDS), a clinico-radiological tetrad defined as the presence of…
Abstract Number: 1283 • 2018 ACR/ARHP Annual Meeting
Calcium Pyrophosphate Crystal Deposition in a Cohort of 48 Patients with Gitelman Syndrome
Emilie Chotard¹, Anne Blanchard², Gilles Gailly¹, Rosa Vargas-Poussou³ and Hang-Korng Ea^4,5, ¹AP-HP, Hôpital Lariboisière, service de rhumatologie, centre Viggo Petersen, PARIS, France, ²AP-HP, Hôpital Européen Georges Pompidou, Service de néphrologie, PARIS, France, ³AP-HP, Hôpital Européen Georges Pompidou, Service de génétique, PARIS, France, ⁴AP-HP, Hôpital Lariboisière, service de rhumatologie, centre Viggo Petersen, Paris, France, ⁵INSERM UMR1132, Bioscar, University Paris Diderot, PARIS, France
Background/Purpose: Gitelman syndrome (GS) is a rare recessively inherited tubulopathy, caused by inactive mutations in SLC12A3 gene encoding the thiazide-sensitive-sodium-chloride transporter. It is characterized by…
Abstract Number: 2223 • 2018 ACR/ARHP Annual Meeting
Proton Pump Inhibitors and Risk of Calcium Pyrophosphate Deposition (CPPD) in a Population-Based Study
Tuhina Neogi¹, Christine Peloquin¹, Yuqing Zhang^1,2, Hyon K. Choi³, Robert Terkeltaub⁴ and David T. Felson¹, ¹Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ²Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ³Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, ⁴VA San Diego Healthcare System, San Diego, CA
Background/Purpose: There are no therapies available that specifically target CPPD, with treatment limited to symptomatic management. Hypomagnesemia is a recognized risk factor for CPPD, and…
Abstract Number: 1126 • 2017 ACR/ARHP Annual Meeting
High Osteoprotegerin:RANKL Ratios in Synovial Fluid Correlate with the Presence of Calcium Pyrophosphate Crystals
Ian Chang¹, Daisy Obiora², Ann Rosenthal³ and Charlene J. Williams⁴, ¹Medicine/Rheumatology, Medical College of Wisconsin, Milwaukee, WI, ²Urology, Cooper Hospital, Camden, NJ, ³Division of Rheumatology, Medical College of Wisconsin, Milwaukee, WI, ⁴Department of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ
Background/Purpose: Calcium pyrophosphate deposition disease (CPDD) is a common cause of both acute and chronic arthritis in the elderly. It is estimated that twenty percent…
Abstract Number: 2083 • 2017 ACR/ARHP Annual Meeting
The Inflammation Induced By Four Types of Calcium Pyrophosphate Crystals Depends on Their Capacity to Stimulate NF-κb and MAPK Pathways
Félix Renaudin¹, Laure Campillo-Gimenez², Pierre Gras³, Christèle Combes⁴, Martine Cohen-Solal¹, Frederic Liote⁵ and Hang-Korng Ea¹, ¹INSERM UMR1132, Paris Diderot University, Paris, France, ²Inserm UMR1132 Bioscar, Paris, France, ³CIRIMAT, INPT-UPS-CNRS, Toulouse, France, ⁴ENSIACET, CIRIMAT, INPT-UPS-CNRS, Toulouse, France, ⁵University Paris Diderot, Paris, France
Background/Purpose: Calcium pyrophosphate (CPP) crystal-induced inflammation is mainly driven by interleukin (IL)-1β. IL-1β production involves a two-step process including the formation of pro-IL-1β through NF-κB…
Abstract Number: 2271 • 2016 ACR/ARHP Annual Meeting
Mutation in Osteoprotegerin Gene: Early-Onset Osteoarthritis and Chondrocalcinosis in a US Family of Italian/German Ancestry
Urooj Qazi¹, Charlene J. Williams², Mark L. Bernstein³, Aaron Charniak⁴, Amaryllis Ortiz², Ann K. Rosenthal⁵, Lucien Cardinal¹ and Alan T. Kaell¹, ¹Internal Medicine, SUNY Stony Brook Medicine-John T Mather Memorial Hospital, Port Jefferson, NY, ²Department of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ, ³Rheumatology, SUNY Stony Brook Medicine-John T Mather Memorial Hospital, Stony Brook, NY, ⁴SUNY Stony Brook Medicine-John T Mather Memorial Hospital, Port Jefferson, NY, ⁵Division of Rheumatology, Medical College of WI, Milwaukee, WI
Background/Purpose: Chondrocalcinosis is characterized by calcium pyrophosphate dihydrate (CPPD) deposition in articular cartilage. It can occur as a rare autosomal dominant disorder with florid early-onset…
Abstract Number: 184 • 2014 ACR/ARHP Annual Meeting
Ultrasound Versus X-Rays Versus Synovial Fluid Analysis for the Diagnosis of Calcium Pyrophosphate Dihydrate Deposition Disease: Is It CPPD?
Georgios Filippou¹, Antonella Adinolfi¹, Sauro Lorenzini², Ilaria Bertoldi¹, Valentina Di Sabatino¹, Valentina Picerno¹, Luca Sconfienza³, Mauro Galeazzi¹ and Bruno Frediani¹, ¹University of Siena, Siena, Italy, ²Clinical medicine and Immunological science, Rheumatology Unit, Azienda Ospedaliera Universitaria Senese, Siena, Italy, ³University of Milan, Milan, Italy
Background/Purpose: The diagnosis of calcium pyrophosphate crystal (CPP) deposition disease (CPPD) is mainly based on the synovial fluid analysis and Xrays. US has demonstrated high…
Abstract Number: 158 • 2014 ACR/ARHP Annual Meeting
Performance of Joint Ultrasonography in the Diagnosis of Suspected Acute Crystal Arthritis : Results of a Prospective Study of 112 Patients
Pascal Zufferey¹, Isabelle Fabreguet¹, Roxana Valcov¹, Alexandre Dumusc¹ and Alexander K. So Sr.², ¹DAL, RHU/CHUV, Lausanne, Switzerland, ²Dal/Rhu, CHUV, Lausanne, Switzerland
Background/Purpose The gold standard for diagnosing gout and CCP arthritis is the identification of monosodium urate (MSU) crystals in joint fluid. Ultrasound (US) features of…
Abstract Number: 1922 • 2012 ACR/ARHP Annual Meeting
Articular Involvement in Relapsing Polychondritis: A Case Series
Laura O. Damian¹, Linda Ghib², Ioana Felea¹, Alma Maniu³, Nadia Radics², Simona Falaus², Ileana Filipescu⁴, Siao-pin Simon⁵ and Simona Rednic⁶, ¹Rheumatology, Emergency Clinical County Hospital Cluj, Cluj-Napoca, Romania, ²Rheumatology, Emergency County Clinical Hospital Cluj Napoca, Cluj Napoca, Romania, ³Otorhynolaringology, University of Medicine and Pharmacy "Iuliu Hatieganu" Cluj Napoca, Cluj Napoca, Romania, ⁴Rheumatology, University of Medicine and Pharmacy "Iuliu Hatieganu" Cluj Napoca, Cluj-Napoca, Romania, ⁵Rheumatology, University of Medicine and Pharmacy "Iuliu Hatieganu" Cluj Napoca, Cluj Napoca, Romania, ⁶Clinical County Emergency Hospital, Cluj-Napoca, Romania
Background/Purpose: Relapsing polychondritis (RP) is a relatively rare, but progressive disease with predilection for cartilage, with few data available regarding the arthritis in this setting.…

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