ACR Meeting Abstracts

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Abstracts tagged "cholinergic agonists and osteoclasts"

  • Abstract Number: 1010 • 2014 ACR/ARHP Annual Meeting

    Catecholaminergic-to-Cholinergic Transition of Sympathetic Nerve Fibers in Arthritis and in a Co-Culture System of Sympathetic Ganglia in Vitro

    Hubert Stangl1, Hans Robert Springorum2, Dominique Muschter2, Susanne Graessel2 and Rainer Straub3, 1Department of Internal Medicine 1, Laboratory of Exp. Rheumatology and Neuroendocrino-Immunology, University Hospital Regensburg, Regensburg, Germany, 2Department of Orthopedic Surgery, Division of Experimental Orthopedic Surgery, University Hospital Regensburg, Regensburg, Germany, 3Internal Medicine, Laboratory of Exp. Rheumatology and Neuroendocrino-Immunology, University Hospital Regensburg, Regensburg, Germany

    Background/Purpose: Sympathetic nerve fibers play an important role in bone and tissue homeostasis of joints. However sympathetic nerve fibers are able to switch their phenotype…
  • Abstract Number: 1825 • 2013 ACR/ARHP Annual Meeting

    Osteoclast Progenitors, Fibroblast-Like Cells and Draining Lymph Node Cells Induce Catecholaminergic-To-Cholinergic Transition Of Sympathetic Nerve Fibers Under Healthy Conditions But Not In Highly Inflamed Arthritic Tissue

    Hubert Stangl1, Dominique Muschter2, Susanne Graessel3 and Rainer H. Straub4, 1Department of Internal Medicine 1, Laboratory of Exp. Rheumatology and Neuroendocrino-Immunology, University Hospital of Regensburg, Regensburg, Germany, 2Department of Orthopedic Surgery, Division of Experimental Orthopedic Surgery, University Hospital Regensburg, Regensburg, Germany, 3Department of Orthopedic Surgery, Division of Experimental Orthopedic Surgery, University Hospital of Regensburg, Regensburg, Germany, 4Department of Internal Medicine I, Laboratory of Exp. Rheumatology and Neuroendocrino-Immunology, University Hospital of Regensburg, Regensburg, Germany

    Background/Purpose: Sympathetic nerve fibers innervate bone and tissue adjacent to joints. They play an important role in bone and tissue homeostasis. Under certain conditions, sympathetic…
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