Abstracts tagged "chemokines and psoriatic arthritis"

Abstract Number: 2070 • 2018 ACR/ARHP Annual Meeting
Activated Tendon Stromal Cells Drive a Type 17 Immune Response Via CCL20: A Potential Role in the Pathogenesis of Enthesitis in Psoriatic Arthritis
Emma Garcia-Melchor¹, Giacomo Cafaro^2,3, Moeed Akbar¹, Derek Gilchrist¹, Susan M Kitson¹, Stefan Siebert⁴, Iain B. McInnes⁵ and Neal L Millar¹, ¹Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom, ²Institute of Infection, Immunity and Inflammation, University of Glasgow, Glagow, United Kingdom, ³Rheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy, ⁴Institute of Infection, Immunity and Inflammation, University of Glasgow, Cardiff, United Kingdom, ⁵Immunology, Infection and Inflammation, University of Glasgow, Glasgow, United Kingdom
Background/Purpose: While the exact pathogenesis of psoriatic arthritis (PsA) remains unclear, it is recognised that several environmental factors operate in individuals with genetic susceptibility leading…
Abstract Number: 3040 • 2016 ACR/ARHP Annual Meeting
Th17 Migration into the Synovial Fluid of Patients with Active Psoriatic Arthritis Is Enhanced By Regulatory T Cells
Helen Baldwin¹, Amara Ezeonyeji², Mohammed Rohan Butt² and Michael R. Ehrenstein³, ¹Rheumatology, University College London, London, United Kingdom, ²Rheumatology, Medicine, University College London, London, United Kingdom, ³Medicine, University College London, London, United Kingdom
Background/Purpose: Uncontrolled migration of Th17 cells into the skin and joints is a major driver in the pathogenesis of psoriatic arthritis (PsA). Modulation of T…

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