Abstracts tagged "Chemokine Receptors and T cells"

Abstract Number: 2733 • 2014 ACR/ARHP Annual Meeting
Decreased CXCR3+CCR4-CCR6+ CD4+ Effector Memory T Cells in Patients with Granulomatosis with Polyangiitis
Lucas L. Lintermans¹, Coen A. Stegeman², Abraham Rutgers¹, Peter Heeringa³ and Wayel H. Abdulahad¹, ¹Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, Netherlands, ²Nephrology, University Medical Center Groningen, Groningen, Netherlands, ³Pathology and Medical Biology, University Medical Center Groningen, Groningen, Netherlands
Background/Purpose: Persistent expansion of circulating CD4+ effector memory T cells (TEM) in patients with Granulomatosis with polyangiits (GPA) suggest their fundamental role in disease pathogenesis.…