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Abstracts tagged "Chemokine Receptors and T cells"

  • Abstract Number: 2733 • ACR/ARHP Annual Meeting 2014

    Decreased CXCR3+CCR4-CCR6+ CD4+ Effector Memory T Cells in Patients with Granulomatosis with Polyangiitis

    Lucas L. Lintermans1, Coen A. Stegeman2, Abraham Rutgers1, Peter Heeringa3 and Wayel H. Abdulahad1, 1Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, Netherlands, 2Nephrology, University Medical Center Groningen, Groningen, Netherlands, 3Pathology and Medical Biology, University Medical Center Groningen, Groningen, Netherlands

    Background/Purpose:  Persistent expansion of circulating CD4+ effector memory T cells (TEM) in patients with Granulomatosis with polyangiits (GPA) suggest their fundamental role in disease pathogenesis.…

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