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Abstracts tagged "certolizumab pegol and joint damage"

  • Abstract Number: 2472 • 2014 ACR/ARHP Annual Meeting

    The First, Multicenter, Double-Blind, Randomized, Parallel-Group Study of Certolizumab Pegol in Early Rheumatoid Arthritis Demonstrates Inhibition of Joint Damage Progression

    Tatsuya Atsumi1, Kazuhiko Yamamoto2, Tsutomu Takeuchi3, Hisashi Yamanaka4, Naoki Ishiguro5, Yoshiya Tanaka6, Katsumi Eguchi7, Akira Watanabe8, Hideki Origasa9, Toshiharu Shoji10, Osamu Togo11, Toshiyuki Okada12, Désirée M. van der Heijde13, Nobuyuki Miyasaka14 and Takao Koike15,16, 1Division of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan, 2Department of Allergy and Rheumatology, The University of Tokyo, Tokyo, Japan, 3Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Kitakyushu, Japan, 4Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 5Department of orthopedics, Nagoya University Graduate School and Faculty of Medicine, Nagoya, Japan, 6The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 7Department of Rheumatology, Sasebo City General Hospital, Nagasaki, Japan, 8Division of Rheumatology, Department of Internal Medicine, School of Medicine, Tohoku University, Tokyo, Japan, 9Division of Biostatistics and Clinical Epidemiology, University of Toyama School of Medicine, Toyama, Japan, 10Department of Clinical Research and Development, UCB Pharma, Tokyo, Japan, 11Biometrics Group, UCB Pharma, Tokyo, Japan, 12Astellas Pharma Inc, Tokyo, Japan, 13Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 14Department of Rheumatology, Tokyo Medical and Dental University, Tokyo, Japan, 15NTT Sapporo Medical Center, Sapporo, Japan, 16Hokkaido University Graduate School of Medicine, Sapporo, Japan

    Background/Purpose The efficacy and safety of certolizumab pegol (CZP)+methotrexate (MTX) therapy compared to MTX alone, in Japanese MTX-naïve early rheumatoid arthritis (RA) patients (pts) with…
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