Abstracts tagged "Cell Migration and fibroblasts"

Abstract Number: 1282 • ACR/ARHP Annual Meeting 2013
Effect of RC-3095, An Antagonist of Gastrin-Releasin Peptide Receptor, Regulating Synovial Fibroblasts in Experimental Arthritis
Patricia Oliveira¹, Lidiane Filippin², Mirian Farinon², Vanessa Clarimundo², Gilberto Schwartsmann² and Ricardo M. Xavier³, ¹Rheumatology, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil, ²Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, ³Rheumatology Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
Background/Purpose: The gastrin-releasing peptide (GRP) is the mammalian homologue of the bombesin (BN), and its receptor signaling is involved in several functions, including inflammatory response.…