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Abstracts tagged "CD123"

  • Abstract Number: 1064 • 2019 ACR/ARP Annual Meeting

    CD123+ Plasmacytoid Dendritic Cells from Systemic Sclerosis Patients Are Susceptible to the Cytotoxic Activity of Tagraxofusp, a CD123-Targeted Therapy

    Ross Lindsay1, Janice Chen 1, Robert Spiera 2, Jessica Gordon 2, Marie-Dominique Ah Kioon 3, Franck Barrat 3 and Christopher Brooks 1, 1Stemline Therapeutics, New York, 2Hospital for Special Surgery, New York, NY, 3HSS Research Institute, Hospital for Special Surgery, New York

    Background/Purpose: Tagraxofusp is a novel targeted therapy directed to the interleukin-3 receptor (CD123). Tagraxofusp is comprised of human IL-3 recombinantly fused to a truncated diphtheria…
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