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Abstracts tagged "Catecholamines"

  • Abstract Number: 7 • 2015 ACR/ARHP Annual Meeting

    Influence of TNF on Anti-Inflammatory Tyrosine-Hydroxylase-Positive Synovial Cells in Rheumatoid Arthritis and Osteoarthritis

    Zsuzsa Jenei-Lanzl, Markus Herrmann and Rainer Straub, Laboratory of Experimental Rheumatology and Neuroendocrine Immunology, Department of Internal Medicine, University Hospital Regensburg, Regensburg, Germany

    Background/Purpose: In recent studies we demonstrated that catecholamines produced by tyrosine-hydroxylase-positive (TH+) synovial cells are able to mediate anti-inflammatory effects in rheumatoid arthritis (RA).a TNF…
  • Abstract Number: 1010 • 2014 ACR/ARHP Annual Meeting

    Catecholaminergic-to-Cholinergic Transition of Sympathetic Nerve Fibers in Arthritis and in a Co-Culture System of Sympathetic Ganglia in Vitro

    Hubert Stangl1, Hans Robert Springorum2, Dominique Muschter2, Susanne Graessel2 and Rainer Straub3, 1Department of Internal Medicine 1, Laboratory of Exp. Rheumatology and Neuroendocrino-Immunology, University Hospital Regensburg, Regensburg, Germany, 2Department of Orthopedic Surgery, Division of Experimental Orthopedic Surgery, University Hospital Regensburg, Regensburg, Germany, 3Internal Medicine, Laboratory of Exp. Rheumatology and Neuroendocrino-Immunology, University Hospital Regensburg, Regensburg, Germany

    Background/Purpose: Sympathetic nerve fibers play an important role in bone and tissue homeostasis of joints. However sympathetic nerve fibers are able to switch their phenotype…
  • Abstract Number: 1286 • 2013 ACR/ARHP Annual Meeting

    Anti-Inflammatory Effects Of Tyrosine-Hydroxylase(TH)-Positive Catecholamine Producing Cells In Chronic Arthritis

    Zsuzsa Jenei-Lanzl1, Silvia Capellino2, Frieder Kees3 and Rainer H. Straub4, 1Department of Internal Medicine, University Hospital Regensburg, 1Laboratory of Experimental Rheumatology and Neuroendocrine Immunology, Regensburg, Germany, 22Department of Pediatrics, Division of Endocrinology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA., Baltimore, MD, 3Department of Pharmacology and Toxicology, University of Regensburg, Regensburg, Germany, 4Department of Internal Medicine I, Laboratory of Exp. Rheumatology and Neuroendocrino-Immunology, University Hospital of Regensburg, Regensburg, Germany

    Background/Purpose: In previous studies we have shown that inflammatory processes in experimental arthritis are strongly affected by the sympathetic nervous system (SNS): In the early…
  • Abstract Number: 78 • 2013 ACR/ARHP Annual Meeting

    Norepinephrine (NE) Inhibits Mesenchymal Stem Cell (MSCs) Chondrogenesis By Accelerating Hypertophy – Relevance For Cartilage Regeneration

    Zsuzsa Jenei-Lanzl1, Peter Angele2, Frieder Kees3, Georg Pongratz4 and Rainer H. Straub5, 1Department of Internal Medicine, University Hospital Regensburg, 1Laboratory of Experimental Rheumatology and Neuroendocrine Immunology, Regensburg, Germany, 2Department of Trauma Surgery, University Hospital Regensburg, Germany, Regensburg, Germany, 3Department of Pharmacology and Toxicology, University of Regensburg, Regensburg, Germany, 4Internal Medicine, University Hospital Regensburg, Regensburg, Germany, 5Department of Internal Medicine I, Laboratory of Exp. Rheumatology and Neuroendocrino-Immunology, University Hospital of Regensburg, Regensburg, Germany

    Background/Purpose: The high potential of mesenchymal stem cells (MSCs) in cartilage regeneration is undoubtful. The presence of MSCs in healthy or arthritic cartilage has also…
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