Abstract Number: 1959 • 2014 ACR/ARHP Annual Meeting
Interaction of PDE4 and β-Arrestin Reverses Anti-Inflammatory Effects of Catecholamine-Producing Cells in Chronic Arthritis Via Adrenoceptor Switching from Gαs to GαI Signalling
Background/Purpose In recent studies, we confirmed the anti-inflammatory effects of tyrosine-hydroxylase (TH)-positive catecholamine producing synovial cells in chronic arthritis. Other studies described that inhibitors of…