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Abstracts tagged "cartilage and transforming growth factor"

  • Abstract Number: 56 • ACR/ARHP Annual Meeting 2013

    Age-Related Loss Of The Transforming Growth Factor Beta Receptor ALK5 Precedes Osteoarthritis Development In Cartilage

    Arjan van Caam1, Esmeralda N. Blaney Davidson2, Eva Thijssen1, Wim B. van den Berg1 and Peter M. van der Kraan1, 1Rheumatology Research and Advanced Therapeutics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 2Rheumatology Research & Advanced Therapeutics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands

    Background/Purpose: Osteoarthritis (OA) is the most common joint disease and (old) age is its main risk factor.  One of OA's main hallmarks is degradation of…

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