Abstracts tagged "cartilage and osteoarthritis"

Abstract Number: 2148 • 2013 ACR/ARHP Annual Meeting
Use Of Low Dose Aspirin Is Associated With Reduced Medial Tibial Cartilage Loss In Symptomatic Osteoarthritis: DATA From A Cohort Study
Anita Wluka¹, Changhai Ding², Yuanyuan Wang³, Graeme Jones⁴, Andrew Teichtahl⁵ and Flavia Cicuttini¹, ¹Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia, ²Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, ³Monash University, Melbourne, Australia, ⁴Menzies Research Institute Tasmania, University of Tasmania, HOBART, Australia, ⁵Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
Background/Purpose: Inflammation and vascular disease have recently been shown to play a role in the pathogenesis of osteoarthritis (OA). Low dose aspirin is commonly used…
Abstract Number: 1780 • 2012 ACR/ARHP Annual Meeting
Association Between Chondrocyte Hypertrophy and Angiogenesis of Cartilage in Osteoarthritis
Laurence Pesesse¹, Christelle Sanchez², Jean-Pierre Delcour³, Caroline Baudouin⁴, Philippe Msika⁴ and Yves Henrotin⁵, ¹Bone and Cartilage Research Unit, University of Liège, Liège, Belgium, ²Bone and Cartilage Research Unit, University of Liège, Liege, Belgium, ³Orthopedic surgery, Centre hospitalier du Bois de l'Abbaye, Seraing, Belgium, ⁴IRD Direction, Laboratoires Expanscience, Epernon, France, ⁵University of Liège, Bone and Cartilage Research Unit, Liège, Belgium
Background/Purpose: Chondrocyte hypertrophy is commonly observed in OA cartilage, associated with matrix mineralization and vascularization. In our previous work, we demonstrated that hypertrophic differentiation of…
Abstract Number: 1118 • 2012 ACR/ARHP Annual Meeting
Association Between Hip and Knee Cartilage Measured Using Radiographs and Magnetic Resonance Imaging: The Tasmanian Older Adult Cohort Study
Hussain Ijaz Khan¹, Dawn Dore², Guangju Zhai³, Changhai Ding⁴, Jean Pierre Pelletier⁵, Johanne Martel-Pelletier⁶, Flavia Cicuttini⁷ and Graeme Jones⁸, ¹Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart, 7000, Australia, ²Musculoskeletal Unit, Menzies Research institute Tasmania, University of Tasmania, Hobart, 7000, Australia, ³Discipline of Genetics, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ⁴Musculoskeletal and Epidemilogy, Menzies research institute & Monash University, Hobart, Australia, ⁵Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Notre-Dame Hospital, Montreal, QC, Canada, ⁶Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ⁷Department of Epidemiology and Preventive Medicine, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, 3004, Australia, ⁸Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia
Background/Purpose: Cartilage loss is the key pathological feature of osteoarthritis (OA) and can be assessed indirectly using radiography or directly through magnetic resonance imaging…
Abstract Number: 1120 • 2012 ACR/ARHP Annual Meeting
Cartilage Volume Loss Occurs in Most Older Adults and the Rate of Loss Increases with Age
Andreea M. Harsanyi¹, Dawn Dore², Changhai Ding³, Jean-Pierre Pelletier⁴, Johanne Martel-Pelletier⁴, Flavia Cicutinni⁵ and Graeme Jones³, ¹Menzies Research Institute Tasmania, Hobart, Australia, ²Musculoskeletal Unit, Menzies Research institute Tasmania, University of Tasmania, Hobart, 7000, Australia, ³Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, ⁴Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ⁵Department of Epidemiology and Preventive Medicine, Monash University, Monash University, Melbourne, Australia, Melbourne, Australia
Background/Purpose: Radiographic data suggests knee osteoarthritis is a relatively static disease even over the long term. It is uncertain how much this is influenced by…
Abstract Number: 37 • 2012 ACR/ARHP Annual Meeting
Development of a Mouse Model of Natural Osteoarthritis of Knee by Induction of obesity and Bipedal Walking
Hyun Ah Kim¹, Su Jin Park², Eun-Jeong Cheon³, Hyun A. Jung⁴ and Kyeong Min Son⁵, ¹Division of Rheumatology, Department of Internal Medicine, Hallym university, Kyunggi, South Korea, ²Department of Internal Medicine, Hallym University Sacred Heart Hospital, Kyunggi, South Korea, ³Department of internal medicine, Hallym University Sacred Heart Hospital, Kyunggi, South Korea, ⁴Division of Rheumatology, Department of Internal Medicine, Hallym university sacred heart hospital, Kyunggi, South Korea, ⁵Division of Rheumatology, Department of Internal Medicine, Hallym university Chunchun sacred heart hospital, Chunchun, South Korea
Background/Purpose: Animal models of osteoarthritis(OA) are used extensively in research of its pathogenesis and in search of disease modifying anti-OA drugs. However, whether current animal models…

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