Abstracts tagged "Cardiovascular disease"

Abstract Number: 1253 • 2012 ACR/ARHP Annual Meeting
Identifying Vulnerable Plaque in Rheumatoid Arthritis: A Pilot Study Using Novel Microbubble-Contrast Enhanced Carotid Ultrasonography
Kimberly P. Liang¹, Douglas P. Landsittel², Suresh R. Mulukutla³, Steven E. Reis⁴, Marc C. Levesque¹, Flordeliza S. Villanueva³, Hunter C. Champion⁵ and Larry W. Moreland¹, ¹Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ²Medicine, Biostatistics and Clinical and Translational Science, University of Pittsburgh, Center for Health Care Research Data Center, Pittsburgh, PA, ³Division of Cardiology, University of Pittsburgh, Pittsburgh, PA, ⁴Division of Cardiology and Department of Clinical and Translational Science, University of Pittsburgh, Pittsburgh, PA, ⁵Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Rheumatoid arthritis (RA) is independently associated with a higher risk of cardiovascular disease (CVD). Markers of systemic inflammation, as seen in RA, are associated…
Abstract Number: 210 • 2012 ACR/ARHP Annual Meeting
An Analysis of Metabolic Syndrome in Adult Dermatomyositis with a Focus On Cardiovascular Disease
Mariana T. Moraes¹, Fernando H.C. Souza², Thiago B. M. Barros¹ and Samuel K. Shinjo¹, ¹Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Metabolic syndrome (MetS) is a cluster of metabolic abnormalities associated with increased cardiovascular risk. MetS has been systematically evaluated in all systemic autoimmune rheumatic…
Abstract Number: 1686 • 2012 ACR/ARHP Annual Meeting
Vertebral Fracture Assessment-Detected Abdominal Aortic Calcification Enhances Cardiovascular Disease Risk Stratification of Rheumatoid Arthritis Patients
Ausaf Mohammad¹, Derek Lohan², Diane Bergin², Sarah Mooney², John Newell³, Martin O'Donnell⁴, Robert J. Coughlan¹ and John J. Carey¹, ¹Rheumatology, Galway University Hospitals, Galway, Ireland, ²Radiology, Galway University Hospitals, Galway, Ireland, ³Clinical Research Facility, National University of Ireland, Galway, Ireland, ⁴Clinical Research Facility, Galway University Hospitals, Galway, Ireland
Vertebral Fracture Assessment-detected Abdominal Aortic Calcification Enhances Cardiovascular Disease Risk Stratification of Rheumatoid Arthritis Patients Background/Purpose: Osteoporosis and cardiovascular disease (CVD) are major comorbidities and CVD…
Abstract Number: 1255 • 2012 ACR/ARHP Annual Meeting
Vascular Calcification On Hand and Feet X-Rays, VFA Imaging of the Spine, and Cardiovascular Disease in Rheumatoid Arthritis
Ausaf Mohammad¹, Collette English², Derek Lohan², Diane Bergin², Sarah Mooney², John Newell³, Martin O'Donnell⁴, Robert J. Coughlan¹ and John J. Carey¹, ¹Rheumatology, Galway University Hospitals, Galway, Ireland, ²Radiology, Galway University Hospitals, Galway, Ireland, ³Clinical Research Facility, National University of Ireland, Galway, Ireland, ⁴Clinical Research Facility, Galway University Hospitals, Galway, Ireland
Vascular Calcification on Hand and Feet X-rays, VFA imaging of the spine, and Cardiovascular Disease in Rheumatoid ArthritisBackground/Purpose: Patients with rheumatoid arthritis (RA) are at…
Abstract Number: 161 • 2012 ACR/ARHP Annual Meeting
Increased Serum Uric Acid: Consequence or Cause of Increased Cardiovascular Risk
Inger L. Meek¹, Harald E. Vonkeman² and Mart A.F.J. van de Laar³, ¹Rheumatology & Clinical Immunology, Rheumatology Center Twente, Medisch Spectrum Twente & Twente University, Enschede, Netherlands, ²Rheumatology Center Twente, Medisch Spectrum Twente & Twente University, Enschede, Netherlands, ³Rheumatology, Medisch Spectrum Twente & University of Twente, Enschede, Netherlands
Background/Purpose: Reports on cardiovascular (CV) disease in hyperuricemia and gout show conflicting results. Some studies show hyperuricemia to be an independent risk factor for CV…
Abstract Number: 1668 • 2012 ACR/ARHP Annual Meeting
Improving the Accuracy of Cardiovascular Risk Prediction in Rheumatoid Arthritis with a New Predictive Model Using the 10-Year Prospective Carre-Study
Alper M. van Sijl¹, Inge A.M. van den Oever¹, Mike J.L. Peters², Vokko P. van Halm³, Alexandre E. Voskuyl⁴, Yvo M. Smulders⁵ and Mike T. Nurmohamed¹, ¹Rheumatology, Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, ²Internal medicine, VU University Medical Center, Amsterdam, Netherlands, ³Cardiology, Academic Medical Centre, Amsterdam, Netherlands, ⁴Rheumatology, VU University Medical Center, Amsterdam, Netherlands, ⁵Internal Medicine, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory joint disease which is associated with an increased cardiovascular (CV) risk. Traditional CV risk factors do not…
Abstract Number: 1198 • 2012 ACR/ARHP Annual Meeting
Cardiovascular Risk Factors and Events Are More Frequent Prior to the Onset of Rheumatoid Arthritis Than in the General Population
Helen Pahau Sr.¹, Vibeke Videm², Sanjoy Paul³ and Ranjeny Thomas⁴, ¹Diamantina Institute, University of Queensland Diamantina Institute, Brisbane, Australia, ²Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, and Department of Immunology and Transfusion Medicine, Trondheim University Hospital,, Trondheim, Norway, ³University of Queensland School of Population Health, Brisbane, Australia, ⁴University of Queensland Diamantina Institute, Brisbane, Australia
Background/Purpose: Patients with the inflammatory autoimmune disease Rheumatoid Arthritis (RA) have a higher mortality and morbidity than the general population, predominantly related to cardiovascular disease…
Abstract Number: 165 • 2012 ACR/ARHP Annual Meeting
Colchicine Is Associated with a Decreased Rate of Myocardial Infarction in Gout Patients: Interim Results From a Retrospective Cohort Study
Daria B. Crittenden¹, Cilian J. White¹, Michael DeBerardine¹, Grace Kim², Binita Shah³, Jessica C. Kimmel¹, Rima D. Patel¹, Steven P. Sedlis³, Jeffrey D. Greenberg⁴, Craig T. Tenner⁵, Bruce N. Cronstein¹ and Michael H. Pillinger¹, ¹Internal Medicine, NYU School of Medicine, Division of Rheumatology, New York, NY, ²NYU School of Medicine, Division of Rheumatology, New York, NY, ³NYU School of Medicine, Division of Cardiology, New York, NY, ⁴Division of Rheumatology, Department of Medicine, NYU Hospital for Joint Diseases, New York, NY, ⁵Internal Medicine, NYU School of Medicine, Department of Internal Medicine, New York, NY
Background/Purpose: Atherosclerosis is an inflammatory process, but to date no anti-inflammatory agent has definitively been shown to alter cardiovascular (CV) risk. Colchicine is an anti-inflammatory…
Abstract Number: 2568 • 2012 ACR/ARHP Annual Meeting
The Risk of Pulmonary Embolism and Deep Vein Thrombosis in Giant Cell Arteritis: A Population-Based Cohort Study
J. Antonio Avina-Zubieta¹, Diane Lacaille², Eric C. Sayre³, Jacek A. Kopec³ and Hyon Choi⁴, ¹Rheumatology, Arthritis Research Centre of Canada, University of British Columbia, Richmond, BC, Canada, ²Rheumatology, Arthritis Research Centre of Canada/University of British Columbia, Richmond, BC, Canada, ³Arthritis Research Centre of Canada, Richmond, BC, Canada, ⁴Section of Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, Arthritis Research Centre of Canada/University of British Columbia, Boston, MA
Background/Purpose: A recent hospital-based study has suggested an 8 fold increased risk of pulmonary embolism (PE) in individuals with polymyalgia rheumatica in the year following…
Abstract Number: 1651 • 2012 ACR/ARHP Annual Meeting
Higher Corticosteroid Doses Early in Disease Have A Long-Term Influence On Metabolic Syndrome in Systemic Lupus Erythematosus: Data from an International Inception Cohort
Ben Parker¹, Murray B. Urowitz², Dafna D. Gladman³, Mark Lunt⁴, Ian N. Bruce⁵ and Systemic Lupus International Collaborating Clinic (SLICC)⁶, ¹Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, United Kingdom, ²Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁴Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester, United Kingdom, ⁵Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit and NIHR Manchester Musculoskeletal Biomedical Research Unit, The University of Manchester, Manchester, United Kingdom, ⁶Toronto
Background/Purpose: The Metabolic Syndrome (MetS) is a clustering of metabolic abnormalities associated with an increased risk of developing diabetes and atherosclerosis, and may add to…
Abstract Number: 872 • 2012 ACR/ARHP Annual Meeting
Monocyte Chemoattractant Protein-1 and Eotaxin Are Associated with Parameters of Cardiac Dysfunction in Juvenile Dermatomyositis
Thomas Schwartz¹, Ivar Sjaastad², Berit Flatø³, Maria Vistnes¹, Geir Christensen¹ and Helga Sanner³, ¹Institute for Experimental Medical Research, Institute for Clinical Medicine, University of Oslo, Oslo, Norway, ²Institute for Clinical Medicine, University of Oslo, Institute for Experimental Medical Research, Oslo University Hospital, Oslo, Norway, ³Department of Rheumatology, Oslo University Hospital, Institute for Clinical Medicine, University of Oslo, Oslo, Norway
Background/Purpose : Juvenile dermatomyositis (JDM) is a vasculopathic disease affecting not only skeletal muscle and skin, but other organs as well. Previously we have shown…
Abstract Number: 68 • 2012 ACR/ARHP Annual Meeting
Cardiovascular Comorbidities Antedating the Diagnosis of Rheumatoid Arthritis
Anne M. Kerola¹, Tuomas Kerola², Markku J. Kauppi², Hannu Kautiainen³, Lauri J. Virta⁴, Kari Puolakka⁵ and Tuomo Nieminen⁶, ¹Medical School, University of Helsinki, Helsinki, Finland, ²Department of Internal Medicine, Päijät-Häme Central Hospital, Lahti, Finland, ³Unit of Primary Health Care, Kuopio University Hospital, Kuopio, Finland, ⁴Research Department, the Social Insurance Institution, Turku, Finland, ⁵Department of Medicine, South Karelia Central Hospital, Lappeenranta, Finland, ⁶Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased cardiovascular morbidity. Evidence suggests that RA patients are at an increased risk of…
Abstract Number: 2563 • 2012 ACR/ARHP Annual Meeting
Factors Associated with Major Cardiovascular Events in Patients with Primary Systemic Necrotizing Vasculitides: Results of a Longitudinal Long-Term Follow-up Study
Benjamin Terrier¹, Christian Pagnoux², Gilles Chironi³, Alain Simon³, Luc Mouthon⁴, Loic Guillevin⁵ and French Vasculitis Study Group (FVSG)⁶, ¹Internal Medicine, Cochin University Hospital, Paris, France, ²Rheumatology, Mount Sinai Hospital, Toronto, Canada, Toronto, ON, Canada, ³HEGP, Paris, France, ⁴Internal Medicine, Hopital Cochin, Paris, France, ⁵Internal Medicine, Division of Internal Medicine, Hôpital Cochin, University Paris Descartes, Paris, France, ⁶Paris
Background/Purpose: Primary systemic necrotizing vasculitides (SNV) were shown to be associated with more frequent subclinical atherosclerosis, independently of cardiovascular (CV) risk factors and C-reactive protein…
Abstract Number: 1443 • 2012 ACR/ARHP Annual Meeting
Caspase-1 Modulates Endothelial Dysfunction and Vascular Repair in Murine Lupus
J. Michelle Kahlenberg¹, Wenpu Zhao², Srilakshmi Yalavarthi² and Mariana J. Kaplan³, ¹Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI, ²University of Michigan Rheumatology, Ann Arbor, MI, ³Systemic Autoimmunity Branch, National Institutes of Health/NIAMS, Bethesda, MD
Background/Purpose: Premature cardiovascular disease (CVD) represents a significant cause of morbidity and mortality in systemic lupus erythematosus (SLE). We recently proposed that type I interferon…
Abstract Number: 820 • 2012 ACR/ARHP Annual Meeting
In Rheumatoid Arthritis Incident Fractures Are Associated with an Increased Risk of Cardiovascular Events
Orla Ni Mhuircheartaigh¹, Cynthia S. Crowson², Sherine E. Gabriel³, Veronique L. Roger⁴, L. Joseph Melton III⁵ and Shreyasee Amin⁶, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ³Health Sciences Research & Div of Rheumatology, Mayo Clinic, Rochester, MN, ⁴Health Sciences Research and Cardiology, Mayo Clinic, Rochester, MN, ⁵Department of Hlth Sciences, Mayo Clinic, Rochester, MN, ⁶Health Sciences Research and Rheumatology, Mayo Clinic, Rochester, MN
Background/Purpose: Rheumatoid Arthritis (RA) is associated with an increased risk for both fracture (fx) and cardiovascular disease (CVD) and there is increasing evidence establishing a…

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