Abstracts tagged "Cardiovascular disease"

Abstract Number: 469 • 2013 ACR/ARHP Annual Meeting
Anti-TNF Therapy Induces Positive Changes In The Lipoprotein Profile Of RA Patientes. Results Of a Prospective Study
Jaime Calvo-Alén¹, Carmela Baamonde², Ignacio Villa¹, Víctor Martínez-Taboada³, Mario Agudo⁴ and Juan Gómez-Gerique⁵, ¹Rheumatology, Hospital Universitario Sierrallana, Torrelavega, Spain, ²Biochemistry, Hospital Universitario Sierrallana, Torrelavega, Spain, ³Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, ⁴Rheumatology, Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, ⁵Biochemistry, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain
Background/Purpose: Anti-TNF therapy induces elevations in total cholesterol levels although does not seem to modify the atherogenic index. Otherwise, it appears to have a cardiovascular…
Abstract Number: 377 • 2013 ACR/ARHP Annual Meeting
Risk Factors For Stroke In Patients With Rheumatoid Arthritis
Anja Strangfeld¹, Yvette Meißner², Adrian Richter³, Matthias Schneider⁴, Hans Peter Tony⁵, Kerstin Gerhold⁶, Angela Zink⁷ and Joachim Listing³, ¹Programme Area Epidemiology, German Rheumatism Research Center, a Leipniz Institute, Berlin, Germany, ²Programme Area Epidemiology, German Rheumatism Research Center Berlin, Berlin, Germany, ³German Rheumatism Research Center, Berlin, Germany, ⁴Department of Endocrinology, Diabetes and Rheumatology, University of Duesseldorf, Duesseldorf, Germany, ⁵Rheumatology/Immunology, University of Würzburg, Würzburg, Germany, ⁶Programme Area of Epidemiology, German Rheumatism Research Center, a Leipniz Institute, Berlin, Germany, ⁷German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany
Background/Purpose: Patients with rheumatoid arthritis (RA) are at increased risk of stroke. This event is associated with considerable sequelae and might result in death or…
Abstract Number: 2825 • 2013 ACR/ARHP Annual Meeting
The Influence Of Early Menopause On Cardiovascular Risk In Women With Rheumatoid Arthritis
Emily Pfeifer¹, Cynthia S. Crowson², Shreyasee Amin³, Sherine E. Gabriel⁴ and Eric L. Matteson⁵, ¹Department of Medicine, Mayo Clinic, Rochester, MN, ²Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ³Division of Rheumatology, Mayo Clinic, Rochester, MN, ⁴Health Sciences Research & Div of Rheumatology, Mayo Clinic, Rochester, MN, ⁵Rheumatology, Mayo Clinic, Rochester, MN
Background/Purpose: Lifetime exposure to female sex hormones may play a role in the development and severity of rheumatoid arthritis (RA). These same hormones have also…
Abstract Number: 1749 • 2013 ACR/ARHP Annual Meeting
Treatment Strategies and Outcomes In Patients With Systemic Sclerosis and Acute Myocardial Infarction
Priya Prakash¹, Dhaval Kolte¹, Sahil Khera¹, Jagadish Khanagavi¹, Marjan Mujib², Chandrasekar Palaniswamy³, Farrah Gutwein⁴, Sachin Sule¹, Wilbert S. Aronow³, William H. Frishman³ and Julia Ash⁴, ¹Medicine, New York Medical College, Valhalla, NY, ²Internal Medicine, New York Medical College, Valhalla, NY, ³Cardiology, New York Medical College, Valhalla, NY, ⁴Rheumatology, New York Medical College, Valhalla, NY
Background/Purpose: , Systemic Sclerosis (SSc) is associated with an increased risk of cardiovascular diseases, including acute myocardial infarction (AMI). However, whether SSc influences treatment choice and…
Abstract Number: 895 • 2013 ACR/ARHP Annual Meeting
The Relative Risk Of Aortic Aneurysm In Patients With Giant Cell Arteritis Compared With The General Population
Joanna Robson¹, Amit Kiran², Joseph Maskell³, Andrew Hutchings⁴, Nigel K. Arden⁵, Bhaskar Dasgupta⁶, William Hamilton⁷, Akan Emin⁸, David Culliford³ and Raashid A. Luqmani², ¹Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, United Kingdom, ²Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, United Kingdom, ³Faculty of Medicine, University of Southampton, Southampton, United Kingdom, ⁴Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom, ⁵NDORMS; MRC Lifecourse Epidemiology Unit, Oxford NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, United Kingdom, ⁶Rheumatology, Southend University Hospital, Westcliff-on-sea, United Kingdom, ⁷Primary Care Diagnostics, University of Exeter Medical School, Exeter, United Kingdom, ⁸Clinical Effectiveness Unit, The Royal College of Surgeons of England, London, United Kingdom
Background/Purpose: To evaluate the risk of aortic aneurysm in patients with giant cell arteritis (GCA) when compared with age, gender and location matched controls from…
Abstract Number: 470 • 2013 ACR/ARHP Annual Meeting
Sarilumab, a Subcutaneously Administered, Fully Human Monoclonal Antibody Inhibitor Of The IL-6 Receptor Alpha: Relationship Between Inflammation Suppression and Changes In Cholesterol Levels
Christina Charles-Schoeman¹, Steven P. Weinstein², Janet van Adelsberg³, Tanya Momtahen⁴, Richard Wu⁵, Neil Graham⁶ and Stefano Fiore⁷, ¹Medicine-Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, ²Clinical Development, Regeneron Pharmaceuticals Inc, Tarrytown, NY, ³Clinical Science, Regeneron Pharmaceutials, Inc., Tarrytown, NY, ⁴Program Direction, Sanofi, Bridgewater, NJ, ⁵BioStatistics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, ⁶Program Direction, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, ⁷Clinical Science, Sanofi, Bridgewater, NJ
Background/Purpose: Sarilumab (SAR) is a fully human monoclonal antibody directed against the alpha subunit of the IL-6 receptor (IL-6Rα) which is currently being evaluated for…
Abstract Number: 358 • 2013 ACR/ARHP Annual Meeting
Inflammatory Burden Predicts Carotid Plaque Progression and Subsequent Cardiovascular Events In Rheumatoid Arthritis: The 2-Year Prospective Cohort Study
Churl Hyun Im¹, Sang Hoon Kwon², Jeong Soo Eun¹, Na Ri Kim¹, Eon Jeong Nam¹ and Young Mo Kang³, ¹Internal Medicine (Rheumatology), Kyungpook National University School of Medicine, Daegu, South Korea, ²Internal medicine (Rheumatology), Kyungpook National University School of Medicine, Daegu, South Korea, ³Department of Internal Medicine (Rheumatology), Kyungpook National University School of Medicine, Daegu, South Korea
Background/Purpose: Rheumatoid arthritis (RA) patients have increased prevalence of carotid atherosclerosis, especially plaque formation, which has been associated with inflammatory burden in a previous study.…
Abstract Number: 2826 • 2013 ACR/ARHP Annual Meeting
Performance Of Five Current Risk Algorithms In Predicting Cardiovascular Events In Rheumatoid Arthritis Patients
Elke.E.A. Arts¹, Calin Popa¹, Alfons A. den Broeder², Anne G. Semb³, Tracey Toms⁴, George Kitas⁴, Piet L.C.M. van Riel¹ and Jaap Fransen⁵, ¹Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, ³Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴Rheumatology, Dudley Group of Hospitals NHS Trust, Russells Hall Hospital, Dudley, United Kingdom, ⁵Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
Background/Purpose: Cardiovascular risk in rheumatoid arthritis (RA) is increased. The cardiovascular (CV) risk algorithms used in the general population may underestimate the risk of cardiovascular…
Abstract Number: 1746 • 2013 ACR/ARHP Annual Meeting
Pericardial Effusions Are Not a Poor Prognostic Factor In Systemic Sclerosis Patients With Pulmonary Hypertension
Elana J. Bernstein¹, Jessica K. Gordon², Wei-Ti Huang³ and Virginia D. Steen⁴, ¹Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ²Rheumatology, Hospital for Special Surgery, New York, NY, ³Biostatistics, Hospital for Special Surgery, New York, NY, ⁴Department of Rheumatology, Georgetown University Medical Center, Washington, DC
Background/Purpose: Pulmonary hypertension (PH) (defined as a mean pulmonary arterial pressure ≥ 25 mmHg on right heart catheterization) is a leading cause of death in…
Abstract Number: 887 • 2013 ACR/ARHP Annual Meeting
Atherosclerosis and Cardiovascular Disease In Systemic Lupus Eryhematosus Are Related To An Inflammatory/Oxidative Status Linked To The Autoimmune Condition and The Clinical Activity Of The Disease. Effect Of Statins Treatment
Chary Lopez-Pedrera¹, Patricia Ruiz-Limon¹, Carlos Perez-Sanchez¹, Mª Angeles Aguirre², Nuria Barbarroja¹, Tomás Cerdó-Ráez³, Maria Laura Bertolaccini⁴, Munther A. Khamashta⁵, Antonio Rodriguez-Ariza⁶, Yolanda Almaden⁷, Husam Khraiwesh⁸, Jose Antonio Gonzalez-Reyes⁹, Jose Manuel Villalba¹⁰, Eduardo Collantes¹¹ and Mª Jose Cuadrado¹², ¹Rheumatology Unit, IMIBIC-Reina Sofia University Hospital, Cordoba, Spain, ²Rheumatology, IMIBIC-Reina Sofia Hospital, Cordoba, Spain, ³Imibic, Córdoba, Spain, ⁴Lupus Research Unit, The Rayne Institute, Kings College London School of Medicine, London, United Kingdom, ⁵Lupus Research Unit, The Rayne Institute, St Thomas Hospital, Kings College London School of Medicine, London, United Kingdom, ⁶Oncology Service and Research Unit, IMIBIC-Reina Sofia Hospital, Cordoba, Spain, ⁷Imibic, Códoba, Spain, ⁸UCO, Córdoba, Spain, ⁹Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain, ¹⁰Cell Biology, Physiology and Immunology, University of Cordoba, Agrifood Campus of International Excelence (ciA3), Cordoba, Spain, ¹¹Rheumatology, Hospital Reina Sofia, Cordoba, Spain, ¹²Lupus Research Unit, The Rayne Institute, London, United Kingdom
Background/Purpose: Atherosclerosis (AT) and cardiovascular disease (CVD) are enhanced systemic lupus erythematosus (SLE). Although there is evidence that statins have anti-inflammatory properties, their mechanism of…
Abstract Number: 475 • 2013 ACR/ARHP Annual Meeting
Alteration Of Aortic Distensibility Within 6 Months Of Treatment In RA Patients: An Observational Comparison Of Infliximab and Synthetic Dmards
Birgul Ay¹, Dilek Keskin², Goksal Keskin³ and Ayhan Dinc⁴, ¹Internal Medicine, DYB Research and Training Hospital, Ankara, Turkey, ²Immunology, DYB Research and Training Hospital, Ankara, Turkey, ³Internal Medicine and Clinical Immunology, DYB Research and Training Hospital, Ankara, Turkey, ⁴Rheumatology, Patio Clinic, Ankara, Turkey
Background/Purpose: The proximal aorta accounts for most of the global arterial stiffening and subsequent complications. Aortic stiffness can be demonstrated by changes in aortic dimensions…
Abstract Number: 359 • 2013 ACR/ARHP Annual Meeting
Tocilizumab Treatment Increases Left Ventricular Ejection Fraction and Decreases Left Ventricular Mass Index In Rheumatoid Arthritis Patients Without Cardiac Symptoms : Assessment By Cardiac Magnetic Resonance Imaging At 3.0 Tesla
Hitomi Kobayashi^1,2, Isamu Yokoe³, Hiroshi Sato², Yasuyuki Kobayashi⁴, Kihei Yoneyama⁵, Masaharu Hirano⁶ and Masami Takei⁷, ¹Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ²Rheumatology, Itabashi Chuo Medical Center, Tokyo, Japan, ³Nihon University School of Medicine, Tokyo, Japan, ⁴Radiology, St.Marianna University School of Medicine, Kawasaki, Japan, ⁵Cardiology, St.Marianna University School of Medicine, Kawasaki, Japan, ⁶Cardiology, Tokyo Medical Colleage, Tokyo, Japan, ⁷Division of Hematology and Rheumatology, NIhon University School of Medicine, Tokyo, Japan
Background/Purpose: Left ventricular (LV) dysfunction in rheumatoid arthritis (RA) may result, at least in part, from inflammation that may be regional and global. Therefore, therapies…
Abstract Number: 2828 • 2013 ACR/ARHP Annual Meeting
The Performance Of The Original and An Updated Cardiovascular Risk Algorithm (SCORE) In Patients With Rheumatoid Arthritis
Elke.E.A. Arts¹, Calin Popa¹, Alfons A. den Broeder², Anne Grete Semb³, Tracey Toms⁴, George Kitas⁴, Piet L.C.M. van Riel¹ and Jaap Fransen¹, ¹Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, ³Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴Rheumatology, Dudley Group of Hospitals NHS Trust, Russells Hall Hospital, Dudley, United Kingdom
Background/Purpose: Cardiovascular (CV) risk in rheumatoid arthritis (RA) is increased. The CV risk algorithms for the general population may underestimate the risk of cardiovascular disease…
Abstract Number: 1709 • 2013 ACR/ARHP Annual Meeting
Rheumatoid Arthritis Patient Cardiovascular Disease Prevention Experiences: Qualitative Analysis and Implications
Christie M. Bartels¹, Sarah Tweddell², Barbara Bowers³, Elizabeth Jacobs⁴ and Tonya Roberts³, ¹Rheumatology/Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, ²UW School of Medicine and Public Health, Madison, WI, ³UW School of Nursing, Madison, WI, ⁴Internal Medicine, UW School of Medicine and Public Health, Madison, WI
Background/Purpose: Although rheumatoid arthritis (RA) increases cardiovascular disease (CVD) risk, RA patients receive less CVD preventive care than peers. We previously showed gaps in lipid…
Abstract Number: 804 • 2013 ACR/ARHP Annual Meeting
Tumour Necrosis Factor Inhibitors and The Risk Of Acute Coronary Syndrome In Rheumatoid Arthritis – a National Cohort Study
Lotta Ljung^1,2, Johan Askling³, Solbritt M. Rantapää-Dahlqvist⁴, Lennart T.H. Jacobsson⁵ and The ARTIS Study Group⁶, ¹Clinical epidemiology unit, Karolinska Institutet, Stockholm, Sweden, ²Department for Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Sweden, ³Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, ⁴Department for Public Health and Clinical Medicine/ Rheumatology, Umeå University, Umeå, Sweden, ⁵Department of Rheumatology and Inflammation Research, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, ⁶Karolinska Institutet, Stockholm, Sweden
Background/Purpose: The high risk of ischemic heart disease (IHD) in patients with rheumatoid arthritis (RA) has been linked to inflammation and disease severity. Treatment with…

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