ACR Meeting Abstracts

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Abstracts tagged "Cardiovascular disease"

  • Abstract Number: 450 • 2013 ACR/ARHP Annual Meeting

    Tocilizumab Monotherapy Compared With Adalimumab Monotherapy In Patients With Rheumatoid Arthritis: An Evaluation Of High-Density Lipoprotein Composition

    Cem Gabay1, Katie Tuckwell2, Jennifer Green2, Micki Klearman3 and Arthur Kavanaugh4, 1SCQM registry, University Hospitals of Geneva, Geneva, Switzerland, 2Roche, Welwyn Garden City, United Kingdom, 3Roche, South San Francisco, CA, 4University of California, San Diego, La Jolla, CA

    Background/Purpose: Rheumatoid arthritis (RA) patients (pts) are at increased risk for cardiovascular (CV) disease. Although analysis of lipids such as LDL-C and HDL-C is useful…
  • Abstract Number: 303 • 2013 ACR/ARHP Annual Meeting

    Risk Of Cardiovascular Events In Patients With Psoriatic Arthritis, Psoriasis, and Rheumatoid Arthritis: A General Population-Based Cohort Study

    Alexis Ogdie1, Yiding Yu2, Kevin Haynes3, Samantha Maliha4, Thorvardur Love5,6, Andrea Troxel7, Sean Hennessy8, David Margolis9, Stephen Kimmel10, Nehal N. Mehta11, Hyon Choi12,13 and Joel Gelfand14, 1Rheumatology and Epidemiology, University of Pennsylvania, Philadelphia, PA, 2Medicine, Brigham and Women's Hospital, Boston, MA, 3Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 4University of Pennsylvania, Philadelphia, PA, 5Faculty of Medicine, University of Iceland, Reykjavik, Iceland, 6Landspitali University Hospital, Reykjavik, Iceland, 7Biostatistics and Epidemiology, University of Pennsylvania., Philadelphia, PA, 8Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, 9Dermatology and Epidemiology, University of Pennsylvania, Philadelphia, PA, 10Cardiology and Epidemiology, University of Pennsylvania, Philadelphia, PA, 11National Heart Lung Blood Institute, Cardiovascular and Pulmonary Division, NHLBI, National Institutes of Health, Bethesda, MD, 12Section of Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 13Division of Rheumatology, Allergy, and Immunology Massachusetts General Hospital, Harvard Medical School, Boston, MA, 14Dermatology and Epidemiology, University of Pennsylvania., Philadelphia, PA

    Risk of Cardiovascular Events in Patients with Psoriatic Arthritis, Psoriasis, and Rheumatoid Arthritis: A general population-based cohort studyBackground/Purpose: Psoriatic arthritis (PsA), psoriasis, and rheumatoid arthritis…
  • Abstract Number: 2766 • 2013 ACR/ARHP Annual Meeting

    Improvement In Insulin Resistance Greater With The Use Of Infliximab Following Intensive Treatment Of Early Rheumatoid Arthritis

    Lesley-Anne Bissell1, Elizabeth Hensor2, Sarah L. Mackie2, Agata Burska3, Jackie L. Nam2, Lukasz Kozera2, Helen I. Keen4, Edith Villeneuve2, Heike Eberl5, Helena Donica6, Philip G. Conaghan7, Jacqueline Andrews2, Paul Emery8 and Ann W. Morgan2, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 2NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine, Translational Research in Immune Mediated Inflammatory Diseases, the University of Leeds, Leeds, AL, United Kingdom, 4Leeds, Leeds, United Kingdom, 5Roche Molecular Diagnostics, Burgess Hill, United Kingdom, 6Department of Biochemical Diagnostics, Medical University of Lublin, Lublin, Poland, 7NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, 8Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Background/Purpose: Insulin resistance (IR), N-terminal pro-brain natriuretic peptide (NT-proBNP) and total cholesterol/high density lipoprotein cholesterol ratio (TC/HDL-C) profiles have been proposed as surrogate measures of…
  • Abstract Number: 1672 • 2013 ACR/ARHP Annual Meeting

    Serious Cardiovascular Events Risk Factors In Giant Cell Arteritis. A Population-Based Study In The French Apogee Cohort

    Grégory Pugnet1, Laurent Sailler2, Guillaume Moulis3, Jean-Pascal Fournier4, Robert Bourrel5, Jean-Louis Montastruc6 and Maryse lapeyre-Mestre6, 1Department of Internal Medicine, Toulouse University Hospital, University of Toulouse, INSERM UMR 1027, Toulouse, France, 2Department of Internal Medicine, Toulouse University Hospital, Toulouse, France, 3Clinical Pharmacology Department, Toulouse University Hospital, University of Toulouse, UMR INSERM-UPS 1027, Toulouse, France, 4Toulouse University, INSERM UMR 1027, Toulouse, France, 5Service Médical, Caisse Nationale de l'Assurance Maladie échelon régional, Midi-Pyrénées, Toulouse, France, 6Department of Clinical Pharmacology, Toulouse University Hospital, INSERM U1027, University of Toulouse, France, Toulouse, France

    Background/Purpose: No population-based study has assessed serious cardiovascular events (sCVE) risk factors in Giant Cell Arteritis (GCA). The aim of our study was to identify…
  • Abstract Number: 779 • 2013 ACR/ARHP Annual Meeting

    Low Cardiovascular Mortality Among Early Rheumatoid Arthritis Patients — A Nationwide Register Study 2000—2008

    Anne M. Kerola1, Tuomo Nieminen2, Lauri J. Virta3, Hannu Kautiainen4, Kari Puolakka5, Tuomas Kerola6, Timo Pohjolainen7 and Markku J. Kauppi6, 1Medical School, University of Helsinki, Helsinki, Finland, 2Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland, 3Research Department, the Social Insurance Institution, Turku, Finland, 4Unit of Primary Health Care, Helsinki University Central Hospital, Helsinki, Finland, 5Department of Medicine, South Karelia Central Hospital, Lappeenranta, Finland, 6Department of Internal Medicine, Päijät-Häme Central Hospital, Lahti, Finland, 7ORTON Rehabilitation Centre, ORTON Foundation, Helsinki, Finland

    Background/Purpose: Increased cardiovascular (CV) mortality in established rheumatoid arthritis (RA) is a widely accepted threat, but in early RA or inception cohorts, growing evidence suggests…
  • Abstract Number: 421 • 2013 ACR/ARHP Annual Meeting

    Enhanced Cardiovascular Risk Factor Screening In Rheumatoid Arthritis: Does This Have a Sustained Impact?

    Mark J Ponsford1, Jennifer K. Cooney2, Bethany Anthony3, Fflur A. Huws4, Lauren Evans1, Jeanette Thom5 and Yasmeen Ahmad1, 1Betsi Cadwaladr University Health Board, Peter Maddison Research Centre, Llandudno, United Kingdom, 2School of Sport, Health and Exercise Sciences, School of Sport, Health and Exercise Sciences, Bangor University, George Building, Bangor, Gwynedd, LL57 2PZ, UK., Bangor, United Kingdom, 3Health and Exercise Sciences, School of Sport, Health and Exercise Sciences, Bangor University, George Building, Bangor, Gwynedd, LL57 2PZ, UK., Bangor, United Kingdom, 4Health and Exercise Sciences, Bangor University, School of Sport, Health and Exercise Sciences, Bangor University, George Building, Bangor, Gwynedd, LL57 2PZ, UK., Bangor, United Kingdom, 5School of Sport, Health and Exercise Sciences, Bangor University, George Building, Bangor, Gwynedd, LL57 2PZ, UK., Bangor, United Kingdom

    Background/Purpose: Rheumatoid Arthritis (RA) patients face a burden of cardiovascular disease (CVD) twice that of the general population. RA patients have reduced physical fitness, a…
  • Abstract Number: 285 • 2013 ACR/ARHP Annual Meeting

    Juvenile Idiopathic Arthritis Patients Demonstrate Alterations In HDL Functionality Without Accelerated Subclinical Atherosclerosis

    Preethi Mani1, Kiyoko Uno2, Katherine Wolski3, Steven J. Spalding4, Stephen J. Nicholls5 and M. Elaine Husni6, 1Cleveland Clinic Lerner College of Medicine, Cleveland, OH, 2Cardiovascular medicine, Cleveland Clinic Foundation, Cleveland, OH, 3Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH, 4Pediatric Institute, Department of Pediatric Rheumatology, The Cleveland Clinic, Cleveland, OH, 5Clinical Research Heart & Vascular Institute, Cleveland Clinic Foundation, Cleveland, OH, 6Rheumatology Dept A50, Cleveland Clinic Foundation, Cleveland, OH

    Background/Purpose: Previous literature supports an increase in cardiovascular (CV) morbidity and mortality in adults with inflammatory joint disease, however it is not known whether children with…
  • Abstract Number: 2726 • 2013 ACR/ARHP Annual Meeting

    A Polymorphism In The Mif Gene Is Associated With Cardiovascular Morbidity In Systemic Lupus Erythematosus – a Pilot Study

    Eric F. Morand, Kathryn Connelly and Alberta Y. Hoi, Centre for Inflammatory Diseases, Monash University, Melbourne, Australia

    Background/Purpose: Chronic inflammation is believed to be responsible for accelerated atherosclerotic cardiovascular disease (CVD) in patients with SLE. Macrophage migration inhibitory factor (MIF) is a…
  • Abstract Number: 1674 • 2013 ACR/ARHP Annual Meeting

    Acute Coronary Syndromes In Patients With Giant Cell Arteritis:  A Population Based Retrospective Cohort Study

    P. Deepak Udayakumar1, Arun K. Chandran1, Cynthia S. Crowson2, Kenneth J. Warrington3 and Eric L. Matteson1, 1Rheumatology, Mayo Clinic, Rochester, MN, 2Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 3Division of Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose:  Acute coronary syndrome (ACS) is one of the leading causes of death in the general population. We aimed at assessing the occurrence of ACS…
  • Abstract Number: 783 • 2013 ACR/ARHP Annual Meeting

    Outcome In Patients With Rheumatoid Disease: Simple Screening Tools Predict Cardiovascular Events and Death

    Stefan Kleinert1, Margret Breunig2, Hans-Peter Tony3, Martin Feuchtenberger4, Marc Schmalzing5, Christian Kneitz6, Stefanie Lehmann7, Christiane Angermann7,8, Georg Ertl8 and Stefan Störk7, 1Rheumatology/Clinical Immunology,, University Hospital Würzburg, Würzburg, Germany, 2Dept. of Internal Medicine-Cardiology, University Hospital Würzburg, Würzburg, Wuerzburg, Germany, 3Rheumatology/Clinical Immunology, University of Würzburg, Würzburg, Germany, 4Rheumatologie/Klinische Immunologie, Kreiskliniken Altötting-Burghausen, Burghausen, Germany, 5Rheumatology/Clinical Immunology, University Hospital Würzburg, Würzburg, Germany, 6Internal Medicine II, Hospital Südstadt, Rostock, Germany, 7Comprehensive Heart Failure Center, University of Würzburg, Würzburg, Germany, 8Dept. of Internal Medicine-Cardiology, University Hospital Würzburg, Würzburg, Germany

    Background/Purpose: Patients with rheumatoid disease (RD) have an increased mortality risk compared to the normal population, mainly due to cardiovascular (CV) disease. Only a proportion…
  • Abstract Number: 401 • 2013 ACR/ARHP Annual Meeting

    Chest Pain Is Not Associated With Coronary Atherosclerosis In Patients With Rheumatoid Arthritis and Ankylosing Spondylitis

    Silvia Rollefstad1, Eirik Ikdahl2, Inge C. Olsen3, Jonny Hisdal4, Tore K. Kvien5,6, Anne S. Eirheim2, Terje R. Pedersen6 and Anne G. Semb2, 1Rhuematology, Diakonhjemmet Hospital, Oslo, Norway, 2Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Section of Vascular Investigations, Uslo University Hospital-Aker, Oslo, Norway, 5Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 6Faculty of Medicine, University of Oslo, Oslo, Norway

    Background/Purpose: During cardiovascular (CV) risk stratification in patients with rheumatoid arthritis (RA) and ankylosing spondylitis (AS), it can be difficult to distinguish between chest pain…
  • Abstract Number: 287 • 2013 ACR/ARHP Annual Meeting

    Long-Term Evaluation Of Cardiac Function In Juvenile Idiopathic Arthritis Under Anti-Tumor Necrosis Factor Therapy

    Alessandro C. Lianza1, Nadia E. Aikawa2, Julio C. B. Moraes3, Gabriela N. Leal4, Samira S. Morhy5, Eloisa Bonfa6 and Clovis A. Silva7, 1Radiology, University of São Paulo, Sao Paulo, Brazil, 2Rheumatology, University of São Paulo, Sao Paulo, Brazil, 3Reumatologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 4Radiology Division, University of São Paulo, Sao Paulo, Brazil, 5Radiology Unit, University of São Paulo, Sao Paulo, Brazil, 6Rheumatology Division, University of São Paulo, Sao Paulo, Brazil, 7Children's Institute, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil

    Background/Purpose: Subclinical cardiac involvement was previously described in juvenile idiopathic arthritis (JIA) patients, however there is no data regarding echocardiography and cardiac biomarkers evaluations in…
  • Abstract Number: 2623 • 2013 ACR/ARHP Annual Meeting

    A CT Evaluation Of Pulmonary and Cardiac Lesions In BEHÇET’S Syndrome Patients Without Pulmonary Symptoms

    Emire Seyahi1, Deniz Cebi Olgun2, SerdaL Ugurlu1, Idil Hanci3, Reona Takahashi4 and Hasan Yazici1, 1Division of Rheumatology,Department of Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 2Department of Radiology,, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 3Department of Neurology, Krankrenhaus Nordwest, Frankfurt am Main, Frankfurt, Germany, 4Department of Internal Medicine, Division of Rheumatology, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey

    Background/Purpose:  In Behçet’s syndrome (BS) patients with symptomatic pulmonary artery involvement (PAI) varying and multiple pulmonary parenchymal and cardiac lesions can be seen in thorax CT…
  • Abstract Number: 1576 • 2013 ACR/ARHP Annual Meeting

    Type I Interferon-Mediated Skewing Of The Serotonin Synthesis In Systemic Lupus Erythematosus Is Associated To Cardiovascular Disease

    Christian Lood1, Helena Tydén1, Birgitta Gullstrand2, Cecilia Klint3, Christina Wenglén3, Christoffer T. Nielsen4, Niels H. H. Heegaard5, Andreas Jönsen1 and Anders A. Bengtsson1, 1Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund, Sweden, 2Department of Laboratory Medicine, Section of Microbiology, Immunology and Glycobiology, Lund University, Lund, Sweden, 3R&D, AnaMar AB, Lund, Sweden, 4Department of Clinical Biochemistry, Immunology & Genetics, Statens Serum Institut, Copenhagen S, Denmark, 5Department of Clinical Biochemistry, Immunology & Genetics, Statens Serum Institut, Copenhagen, Denmark

    Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune rheumatic disease characterized by increased expression of type I interferons (IFNs). Indoleamine 2,3-dioxygenase (IDO), a type I…
  • Abstract Number: 746 • 2013 ACR/ARHP Annual Meeting

    Glucocorticoid Treatment and Damage In The Antineutrophil- Cytoplasm Antibody Associated Vasculitides

    Joanna Robson1, Helen Doll2, Ravi Suppiah3, Oliver Flossmann4, Lorraine Harper5, Peter Hoglund6, David Jayne7, Alfred Mahr8, Kerstin Westman9 and Raashid A. Luqmani10, 1Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, United Kingdom, 2Department of Population Health, University of East Anglia, Norwich, United Kingdom, 3Department of Rheumatology, Auckland District Health Board, Auckland, New Zealand, 4Nephrology, Royal Berkshire Hospital, Reading, United Kingdom, 5Nephrology, University of Birmingham, Birmingham, United Kingdom, 6Competence Centre fo Clinical Research, Skane University Hospital, Lund, Sweden, 7Vasculitis and Lupus Clinic, Addenbrookes Hospital University of Cambridge, Cambridge, United Kingdom, 8Department of Internal Medicine, Hospital Saint-Louis, Paris, France, 9Nephrology and Transplantation, Skåne University Hospital Malmö, Lund University, Malmö, Sweden, 10Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, United Kingdom

    Background/Purpose: Granulomatosis with polyangiitis [Wegener's] (GPA) and microscopic polyangiitis (MPA) are antineutrophil-cytoplasm antibody associated vasculitides (AAVs). Damage is quantified by the Vasculitis Damage Index (VDI).…
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