ACR Meeting Abstracts

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Abstracts tagged "Cardiovascular disease"

  • Abstract Number: 887 • 2013 ACR/ARHP Annual Meeting

    Atherosclerosis and Cardiovascular Disease In Systemic Lupus Eryhematosus Are Related To An Inflammatory/Oxidative Status Linked To The Autoimmune Condition and The Clinical Activity Of The Disease. Effect Of Statins Treatment

    Chary Lopez-Pedrera1, Patricia Ruiz-Limon1, Carlos Perez-Sanchez1, Mª Angeles Aguirre2, Nuria Barbarroja1, Tomás Cerdó-Ráez3, Maria Laura Bertolaccini4, Munther A. Khamashta5, Antonio Rodriguez-Ariza6, Yolanda Almaden7, Husam Khraiwesh8, Jose Antonio Gonzalez-Reyes9, Jose Manuel Villalba10, Eduardo Collantes11 and Mª Jose Cuadrado12, 1Rheumatology Unit, IMIBIC-Reina Sofia University Hospital, Cordoba, Spain, 2Rheumatology, IMIBIC-Reina Sofia Hospital, Cordoba, Spain, 3Imibic, Córdoba, Spain, 4Lupus Research Unit, The Rayne Institute, Kings College London School of Medicine, London, United Kingdom, 5Lupus Research Unit, The Rayne Institute, St Thomas Hospital, Kings College London School of Medicine, London, United Kingdom, 6Oncology Service and Research Unit, IMIBIC-Reina Sofia Hospital, Cordoba, Spain, 7Imibic, Códoba, Spain, 8UCO, Córdoba, Spain, 9Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain, 10Cell Biology, Physiology and Immunology, University of Cordoba, Agrifood Campus of International Excelence (ciA3), Cordoba, Spain, 11Rheumatology, Hospital Reina Sofia, Cordoba, Spain, 12Lupus Research Unit, The Rayne Institute, London, United Kingdom

    Background/Purpose: Atherosclerosis (AT) and cardiovascular disease (CVD) are enhanced systemic lupus erythematosus (SLE). Although there is evidence that statins have anti-inflammatory properties, their mechanism of…
  • Abstract Number: 475 • 2013 ACR/ARHP Annual Meeting

    Alteration Of Aortic Distensibility Within 6 Months Of Treatment In RA Patients: An Observational Comparison Of Infliximab and Synthetic Dmards

    Birgul Ay1, Dilek Keskin2, Goksal Keskin3 and Ayhan Dinc4, 1Internal Medicine, DYB Research and Training Hospital, Ankara, Turkey, 2Immunology, DYB Research and Training Hospital, Ankara, Turkey, 3Internal Medicine and Clinical Immunology, DYB Research and Training Hospital, Ankara, Turkey, 4Rheumatology, Patio Clinic, Ankara, Turkey

    Background/Purpose: The proximal aorta accounts for most of the global arterial stiffening and subsequent complications. Aortic stiffness can be demonstrated by changes in aortic dimensions…
  • Abstract Number: 359 • 2013 ACR/ARHP Annual Meeting

    Tocilizumab Treatment Increases Left Ventricular Ejection Fraction and Decreases Left Ventricular Mass Index In Rheumatoid Arthritis Patients Without Cardiac Symptoms : Assessment By Cardiac Magnetic Resonance Imaging At 3.0 Tesla

    Hitomi Kobayashi1,2, Isamu Yokoe3, Hiroshi Sato2, Yasuyuki Kobayashi4, Kihei Yoneyama5, Masaharu Hirano6 and Masami Takei7, 1Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 2Rheumatology, Itabashi Chuo Medical Center, Tokyo, Japan, 3Nihon University School of Medicine, Tokyo, Japan, 4Radiology, St.Marianna University School of Medicine, Kawasaki, Japan, 5Cardiology, St.Marianna University School of Medicine, Kawasaki, Japan, 6Cardiology, Tokyo Medical Colleage, Tokyo, Japan, 7Division of Hematology and Rheumatology, NIhon University School of Medicine, Tokyo, Japan

    Background/Purpose: Left ventricular (LV) dysfunction in rheumatoid arthritis (RA) may result, at least in part, from inflammation that may be regional and global. Therefore, therapies…
  • Abstract Number: 2828 • 2013 ACR/ARHP Annual Meeting

    The Performance Of The Original and An Updated Cardiovascular Risk Algorithm (SCORE)  In Patients With Rheumatoid Arthritis

    Elke.E.A. Arts1, Calin Popa1, Alfons A. den Broeder2, Anne Grete Semb3, Tracey Toms4, George Kitas4, Piet L.C.M. van Riel1 and Jaap Fransen1, 1Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 2Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, 3Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Rheumatology, Dudley Group of Hospitals NHS Trust, Russells Hall Hospital, Dudley, United Kingdom

    Background/Purpose: Cardiovascular (CV) risk in rheumatoid arthritis (RA) is increased. The CV risk algorithms for the  general population may underestimate the risk of cardiovascular disease…
  • Abstract Number: 1709 • 2013 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis Patient Cardiovascular Disease Prevention Experiences: Qualitative Analysis and Implications

    Christie M. Bartels1, Sarah Tweddell2, Barbara Bowers3, Elizabeth Jacobs4 and Tonya Roberts3, 1Rheumatology/Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 2UW School of Medicine and Public Health, Madison, WI, 3UW School of Nursing, Madison, WI, 4Internal Medicine, UW School of Medicine and Public Health, Madison, WI

    Background/Purpose:  Although rheumatoid arthritis (RA) increases cardiovascular disease (CVD) risk, RA patients receive less CVD preventive care than peers. We previously showed gaps in lipid…
  • Abstract Number: 804 • 2013 ACR/ARHP Annual Meeting

    Tumour Necrosis Factor Inhibitors and The Risk Of Acute Coronary Syndrome In Rheumatoid Arthritis – a National Cohort Study

    Lotta Ljung1,2, Johan Askling3, Solbritt M. Rantapää-Dahlqvist4, Lennart T.H. Jacobsson5 and The ARTIS Study Group6, 1Clinical epidemiology unit, Karolinska Institutet, Stockholm, Sweden, 2Department for Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Sweden, 3Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, 4Department for Public Health and Clinical Medicine/ Rheumatology, Umeå University, Umeå, Sweden, 5Department of Rheumatology and Inflammation Research, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 6Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: The high risk of ischemic heart disease (IHD) in patients with rheumatoid arthritis (RA) has been linked to inflammation and disease severity. Treatment with…
  • Abstract Number: 440 • 2013 ACR/ARHP Annual Meeting

    Cardiovascular Safety Findings In Rheumatoid Arthritis Patients Treated With Tofacitinib, A Novel, Oral Janus Kinase Inhibitor

    C. Charles-Schoeman1, P Wicker2, M. A. Gonzalez-Gay3, S. P. Wood4, M.G. Boy4, J. Geier5, D. Gruben4, K. Soma4 and R. Riese4, 1Medicine-Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, 2PW Consulting LLC, Mystic, CT, 3Reumatologia, Hospital Marques De Valdecilla, Santander, Spain, 4Pfizer Inc, Groton, CT, 5Pfizer Inc, New York, NY

    Background/Purpose: Tofacitinib is a novel, oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Here we evaluated the cardiovascular (CV) event rates and…
  • Abstract Number: 334 • 2013 ACR/ARHP Annual Meeting

    The Joint Effect Of Carotid Ultrasound and Preventive Cardiology Referral On Cardiovascular Risk Factor Modification in Psoriatic Arthritis Patients

    Michael Lucke1, Soo Hyun Kim2 and M. Elaine Husni3, 1Rheumatology, Cleveland Clinic, Cleveland, OH, 2Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, 3Rheumatology Dept A50, Cleveland Clinic Foundation, Cleveland, OH

    Background/Purpose: Cardiovascular disease risk is elevated in psoriatic arthritis (PsA) compared to the general population. Prior studies have demonstrated suboptimal evaluation and control of modifiable…
  • Abstract Number: 2760 • 2013 ACR/ARHP Annual Meeting

    Incidence and Severity Of Myocardial Infarction In Subjects Receiving Anti Tumour Necrosis Factor Drugs For Rheumatoid Arthritis: Results From Linking the British Society For Rheumatology Biologics Register For Rheumatoid Arthritis and Myocardial Ischaemia National Audit Project

    Audrey SL Low1, Kimme L. Hyrich2, Mark Lunt3, Louise K. Mercer3, Christopher Gale4,5, Kath Watson6, British Society for Rheumatology Biologics Registers (BSRBR) Control Centre Consortium1, William G. Dixon7, Deborah P. Symmons3,8 and On behalf of the BSRBR9, 1Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester, United Kingdom, 2Arthritis Research UK Epidemiology Unit, Manchester Academic Health Sciences Centre, Institute of Inflammation and Repair, The University of Manchester, Manchester, United Kingdom, 3Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, United Kingdom, 4Division of Epidemiology, Centre for Epidemiology and Biostatistics, University of Leeds, Leeds, United Kingdom, 5Department of Cardiology,York Teaching Hospital NHS Foundation Trust, York, United Kingdom, 6Arthritis Research UK Epidemiology Unit, Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester, United Kingdom, 7The University of Manchester, Manchester, United Kingdom, 8Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, United Kingdom, 9British Society for Rheumatology, London, United Kingdom

    Background/Purpose: Subjects with rheumatoid arthritis (RA) are at increased risk of myocardial infarction (MI) compared to subjects without RA, with the increased risk potentially driven…
  • Abstract Number: 1720 • 2013 ACR/ARHP Annual Meeting

    Risk Of Cardiovascular Disease and Use Of Xanthine Oxidase Inhibitors For Gout

    Seoyoung C. Kim1, Sebastian Schneeweiss2, Niteesh Choudhry3, Jun Liu4, Robert J. Glynn3 and Daniel H. Solomon3, 1Div. of Pharmacoepidemiology and Pharmacoeconomics, Div. of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2Division of Pharmacoepidemiology, Brigham and Women's Hospital, Boston, MA, 3Brigham and Women's Hospital, Boston, MA, 4Division of Pharmaoepidemiology, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Hyperuricemia and gout are associated with an increased risk of hypertension and cardiovascular disease (CVD) such as myocardial infarction (MI) and stroke. Xanthine oxidase…
  • Abstract Number: 805 • 2013 ACR/ARHP Annual Meeting

    Good Response On Tumour Necrosis Factor Inhibitors Are Associated With a Decreased Risk Of Acute Coronary Syndromes In Patients With Rheumatoid Arthritis

    Lotta Ljung1,2, Lennart T.H. Jacobsson3, Solbritt M. Rantapää-Dahlqvist4, Johan Askling5 and The ARTIS Study Group6, 1Clinical epidemiology unit, Karolinska Institutet, Stockholm, Sweden, 2Department for Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Sweden, 3Department of Rheumatology and Inflammation Research, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 4Department for Public Health and Clinical Medicine/ Rheumatology, Umeå University, Umeå, Sweden, 5Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, 6Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: Inflammatory activity, as well as traditional cardiovascular risk factors, have been suggested to underlie the increased risk of coronary disease in patients with rheumatoid…
  • Abstract Number: 450 • 2013 ACR/ARHP Annual Meeting

    Tocilizumab Monotherapy Compared With Adalimumab Monotherapy In Patients With Rheumatoid Arthritis: An Evaluation Of High-Density Lipoprotein Composition

    Cem Gabay1, Katie Tuckwell2, Jennifer Green2, Micki Klearman3 and Arthur Kavanaugh4, 1SCQM registry, University Hospitals of Geneva, Geneva, Switzerland, 2Roche, Welwyn Garden City, United Kingdom, 3Roche, South San Francisco, CA, 4University of California, San Diego, La Jolla, CA

    Background/Purpose: Rheumatoid arthritis (RA) patients (pts) are at increased risk for cardiovascular (CV) disease. Although analysis of lipids such as LDL-C and HDL-C is useful…
  • Abstract Number: 303 • 2013 ACR/ARHP Annual Meeting

    Risk Of Cardiovascular Events In Patients With Psoriatic Arthritis, Psoriasis, and Rheumatoid Arthritis: A General Population-Based Cohort Study

    Alexis Ogdie1, Yiding Yu2, Kevin Haynes3, Samantha Maliha4, Thorvardur Love5,6, Andrea Troxel7, Sean Hennessy8, David Margolis9, Stephen Kimmel10, Nehal N. Mehta11, Hyon Choi12,13 and Joel Gelfand14, 1Rheumatology and Epidemiology, University of Pennsylvania, Philadelphia, PA, 2Medicine, Brigham and Women's Hospital, Boston, MA, 3Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 4University of Pennsylvania, Philadelphia, PA, 5Faculty of Medicine, University of Iceland, Reykjavik, Iceland, 6Landspitali University Hospital, Reykjavik, Iceland, 7Biostatistics and Epidemiology, University of Pennsylvania., Philadelphia, PA, 8Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, 9Dermatology and Epidemiology, University of Pennsylvania, Philadelphia, PA, 10Cardiology and Epidemiology, University of Pennsylvania, Philadelphia, PA, 11National Heart Lung Blood Institute, Cardiovascular and Pulmonary Division, NHLBI, National Institutes of Health, Bethesda, MD, 12Section of Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 13Division of Rheumatology, Allergy, and Immunology Massachusetts General Hospital, Harvard Medical School, Boston, MA, 14Dermatology and Epidemiology, University of Pennsylvania., Philadelphia, PA

    Risk of Cardiovascular Events in Patients with Psoriatic Arthritis, Psoriasis, and Rheumatoid Arthritis: A general population-based cohort studyBackground/Purpose: Psoriatic arthritis (PsA), psoriasis, and rheumatoid arthritis…
  • Abstract Number: 2766 • 2013 ACR/ARHP Annual Meeting

    Improvement In Insulin Resistance Greater With The Use Of Infliximab Following Intensive Treatment Of Early Rheumatoid Arthritis

    Lesley-Anne Bissell1, Elizabeth Hensor2, Sarah L. Mackie2, Agata Burska3, Jackie L. Nam2, Lukasz Kozera2, Helen I. Keen4, Edith Villeneuve2, Heike Eberl5, Helena Donica6, Philip G. Conaghan7, Jacqueline Andrews2, Paul Emery8 and Ann W. Morgan2, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 2NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine, Translational Research in Immune Mediated Inflammatory Diseases, the University of Leeds, Leeds, AL, United Kingdom, 4Leeds, Leeds, United Kingdom, 5Roche Molecular Diagnostics, Burgess Hill, United Kingdom, 6Department of Biochemical Diagnostics, Medical University of Lublin, Lublin, Poland, 7NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, 8Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Background/Purpose: Insulin resistance (IR), N-terminal pro-brain natriuretic peptide (NT-proBNP) and total cholesterol/high density lipoprotein cholesterol ratio (TC/HDL-C) profiles have been proposed as surrogate measures of…
  • Abstract Number: 1672 • 2013 ACR/ARHP Annual Meeting

    Serious Cardiovascular Events Risk Factors In Giant Cell Arteritis. A Population-Based Study In The French Apogee Cohort

    Grégory Pugnet1, Laurent Sailler2, Guillaume Moulis3, Jean-Pascal Fournier4, Robert Bourrel5, Jean-Louis Montastruc6 and Maryse lapeyre-Mestre6, 1Department of Internal Medicine, Toulouse University Hospital, University of Toulouse, INSERM UMR 1027, Toulouse, France, 2Department of Internal Medicine, Toulouse University Hospital, Toulouse, France, 3Clinical Pharmacology Department, Toulouse University Hospital, University of Toulouse, UMR INSERM-UPS 1027, Toulouse, France, 4Toulouse University, INSERM UMR 1027, Toulouse, France, 5Service Médical, Caisse Nationale de l'Assurance Maladie échelon régional, Midi-Pyrénées, Toulouse, France, 6Department of Clinical Pharmacology, Toulouse University Hospital, INSERM U1027, University of Toulouse, France, Toulouse, France

    Background/Purpose: No population-based study has assessed serious cardiovascular events (sCVE) risk factors in Giant Cell Arteritis (GCA). The aim of our study was to identify…
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