Abstracts tagged "Cardiovascular disease"

Abstract Number: 1579 • 2015 ACR/ARHP Annual Meeting
Association of Myocardial Abnormalities with N-Terminal Pro-Brain Natriuretic Peptide and Disease Activity in Rheumatoid Arthritis without Cardiac Symptoms, Assessed By Cardiac Magnetic Resonance Imaging
Hitomi Kobayashi¹, Yasuyuki Kobayashi², Isamu Yokoe³, Natsumi Ikumi^4,5, Hirotake Inomata⁶, Atsuma Nishiwaki⁶, Noboru Kitamura¹, Kaita Sugiyama⁶, Hidetake Shiraiwa⁶, Masataka Nozaki⁶, Yosuke Nagasawa⁶, Yoshihiro Matsukawa⁵ and Masami Takei¹, ¹Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ²Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, ³Rheumatology, Itabashi Chuo Medical Center, Tokyo, Japan, ⁴Nihon University School of Medicine, Shinjuku, Japan, ⁵Division of Heamatology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ⁶Nihon University School of Medicine, Tokyo, Japan
Background/Purpose: Rheumatoid arthritis (RA) is a multi-organ inflammatory disorder associated with high cardiovascular morbidity and mortality. Cardiac involvements are typically clinically silent, only manifesting as…
Abstract Number: 2129 • 2015 ACR/ARHP Annual Meeting
Treatment-Naïve, Early Rheumatoid Arthritis Patients Demonstrate Abnormalities of Vascular and Myocardial Function on Cardiac MRI
Bara Erhayiem¹, Adam McDiarmid¹, Peter Swoboda¹, Ananth Kidambi¹, David Ripley¹, Tarique Musa¹, Laura Dobson¹, Pankaj Garg¹, Sarah Horton², Raluca Dumitru³, Jacqueline Andrews⁴, John Greenwood⁵, Paul Emery^4,6, Sven Plein¹ and Maya H. Buch^2,7, ¹Leeds Institute of Cardiovascular And Metabolic Medicine, University of Leeds, Leeds, United Kingdom, ²Leeds Institute of Rheumatic & Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ³University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom, ⁴NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁵Leeds Institute of Cardiovascular And Metabolic Medicinee, University of Leeds, Leeds, United Kingdom, ⁶Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁷NIHR - Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom
Treatment-na•ve, early rheumatoid arthritis patients demonstrate abnormalities of vascular and myocardial function on cardiac MRIB Erhayiem, A McDiarmid, PP Swoboda, A Kidambi, DP Ripley, TA…
Abstract Number: 3084 • 2015 ACR/ARHP Annual Meeting
Progression of Lupus Pathology Is Correlative with Cardiac Magnetic Resonance Imaging Abnormalities, Diminished Function, and Inflammatory Histopathology in an Animal Model
Nicholas Young¹, Jeffrey Hampton¹, Saba Aqel¹, Jessica Pyles², Anna Bratasz², Anuradha Kalyanasundaram³, Wael N. Jarjour⁴ and Stacy P. Ardoin⁵, ¹Immunology and Rheumatology, The Ohio State University Medical Center, Columbus, OH, ²Small Animal Imaging Core, The Ohio State University Medical Center, Columbus, OH, ³Physiology and Cell Biology, The Ohio State University Medical Center, Columbus, OH, ⁴Department of Internal Medicine, Division of Immunology and Rheumatology, The Ohio State University Medical Center, Columbus, OH, ⁵Pediatric & Adult Rheumatology, Ohio State University, Columbus, OH
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease causing inflammation throughout the body and cardiovascular involvement is a significant contributor to morbidity and mortality…
Abstract Number: 381 • 2015 ACR/ARHP Annual Meeting
Associations Between Vitamin D Insufficiency, Osteoporotic Fractures and Comorbidites
Eugenio Chamizo Carmona¹, Juan Jose Aznar Sánchez^1,2, Raul Veroz Gonzalez², Tamara Libertad Rodriguez Araya¹, Piter José Cossio Jimenez² and Sara María Rojas Herrera³, ¹Rheumatology, Hospital de Mérida, Mérida, Spain, ²Hospital de Mérida, Mérida, Spain, ³Rheumatolotgy, Hospital de Mérida, Mérida, Spain
Background/Purpose: Vitamin D deficiency is highly prevalence, especially in adults and elderly population. There is controversy about its relationship with increased cardiovascular risk, osteoporosis and…
Abstract Number: 1509 • 2015 ACR/ARHP Annual Meeting
Serum Nitrite Levels in Rheumatoid Arthritis and Relationship to Cardiovascular Risk Factors and Atherosclerosis Biomarkers
Kimberly P. Liang¹, Douglas P. Landsittel², Bernadette B. Sendon³, Donald M. Jones⁴, Rachel Gartland³, Suresh R. Mulukutla⁵, Steven E. Reis⁶, Flordeliza S. Villanueva⁵, Ali Hakim Shoushtari⁷, Cameron Dezfulian⁸ and Larry W. Moreland⁴, ¹Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ²Medicine, University of Pittsburgh, Pittsburgh, PA, ³Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ⁴Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ⁵Division of Cardiology, University of Pittsburgh, Pittsburgh, PA, ⁶Division of Cardiology and Department of Clinical and Translational Science, University of Pittsburgh, Pittsburgh, PA, ⁷Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, PA, ⁸Critical Care Medicine and Clinical and Translational Science, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Nitric oxide (NO) has been implicated in immune regulation, inflammation, arthritis and atherosclerosis. Raised levels of nitrite (NO2) in serum and synovial fluid have…
Abstract Number: 1596 • 2015 ACR/ARHP Annual Meeting
Diagnosis of Carotid Plaque By 4 Cardiovascular Risk Scores in Rheumatoid Arthritis
Raymundo Vera-Pineda¹, Alberto Cardenas-de La Garza², Dionicio A. Galarza-Delgado², Jose Ramon Azpiri-Lopez³, Iris J. Colunga-Pedraza², Judith Garcia-Colunga⁴, Guillermo Elizondo⁴, Mario Alberto Garza-Elizondo², Jesus Zacarias Villarreal-Pérez⁵ and Griselda Serna-Peña⁶, ¹Cardiology., Hospital Universitario, UANL., Monterrey, Mexico, ²Rheumatology, Hospital Universitario, UANL., Monterrey, Mexico, ³Cardiology, Hospital Universitario, UANL., Monterrey, Mexico, ⁴Radiology, Hospital Universitario, UANL., Monterrey, Mexico, ⁵Endocrinology, Hospital Universitario, UANL., Monterrey, Mexico, ⁶Internal Medicine, Hospital Universitario, UANL., Monterrey, Mexico
Background/Purpose: The leading cause of death in RA is atherosclerotic cardiovascular disease (ASCVD). Traditional risk factors do not explain the increased cardiovascular risk (CVR), which…
Abstract Number: 2170 • 2015 ACR/ARHP Annual Meeting
Sleep Efficiency and Cardiovascular Risk Burden in Rheumatoid Arthritis
Samannaaz S. Khoja¹, Gustavo J. Almeida², Mary Chester M. Wasko³ and Sara R. Piva², ¹Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA, ²Physical Therapy, University of Pittsburgh, Pittsburgh, PA, ³Lupus Center, Pittsburgh, PA
Background/Purpose: Sleep is an important physiological process responsible for regulating several metabolic and hormonal processes; hence, poor sleep may negatively impact health. Reduced sleep duration…
Abstract Number: 3117 • 2015 ACR/ARHP Annual Meeting
Under-Treatment of Cardiovascular Risk Factors in Patients with Psoriatic Disease – an International Multicentre Study
Lihi Eder¹, Vinod Chandran¹, Cheryl Rosen², Jan Dutz³, James T. Elder⁴, Proton Rahman⁵, Christopher T. Ritchlin⁶, Francisco A. Tausk⁷, Sherry Rohekar⁸, Richard Hayday⁹, Snezana Barac¹⁰, Devy Zisman¹¹, Joy Feld¹² and Dafna D. Gladman¹, ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Dermatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³University of British Columbia, Vancouver, BC, Canada, ⁴University of Michigan Medical School, Ann Arbor, MI, ⁵Computer Sciences, Memorial University of Newfoundland, St. John's, NF, Canada, ⁶Allergy, Immunology and Rheumatololgy Division, University of Rochester Medical Center, Rochester, NY, ⁷University of Rochester Medical Center, Rochester, NY, ⁸Western University, London, ON, Canada, ⁹University of Manitoba, Winnipeg, MB, Canada, ¹⁰Winnipeg Clinic, Winnipeg, MB, Canada, ¹¹Rheumatology Unit, Carmel Medical Center, Haifa, Israel, ¹²Carmel Medical Center, Haifa, Israel
Background/Purpose: Cardiovascular risk in patients with psoriatic disease is partly attributed to the high prevalence of traditional cardiovascular risk factors in these patients. This study…
Abstract Number: 460 • 2015 ACR/ARHP Annual Meeting
Changes in Body Composition and Metabolic Profile during Treatment with Tocilizumab in Patients with Rheumatoid Arthritis
Anne Tournadre¹, Bruno Pereira², Frederic Dutheil³, Vincent Sapin⁴, Charlotte Giraud⁵, Sandrine Malochet-Guinamand⁶, Thomas Frayssac⁷, Sylvain Mathieu⁵, Jean-Jacques Dubost⁸ and Martin Soubrier⁸, ¹Rheumatology, UNH-UMR 1019 INRA University of Auvergne and Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France, ²Biostatistics unit (DRCI), CHU Clermont-Ferrand, Clermont-Ferrand, France, ³Preventive and Occupational Medicine, CHU G. Montpied Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions EA3533, Clermont-Ferrand, France, ⁴Biochemistry and Molecular Biology Department CHU Clermont-Ferrand, Clermont Université, Université d'Auvergne, EA7281, Clermont-Ferrand, France, ⁵Rheumatology, Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France, ⁶Rheumatology Department,, Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France, ⁷Rheumatology, Rheumatology department CHU Clermont-Ferrand, Clermont-ferrand, France, ⁸Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France
Background/Purpose: Rheumatoid arthritis (RA) is characterized by increased cardiovascular risk and metabolic changes including cachectic obesity, insulin resistance, dyslipidemia. DMARDs decrease inflammation and could thus…
Abstract Number: 1510 • 2015 ACR/ARHP Annual Meeting
The Association Between HDL Cholesterol Efflux Capacity, Citrullinated ApoA1 and Anti-Citrullinated ApoA1 Antibodies in Rheumatoid Arthritis
Katherine Liao¹, Jing Cui¹, Christopher Rhodes², Lauren J. Lahey², Martin Playford³, I-Hsin Kuo¹, Michelle Frits¹, Christine Iannaccone¹, Jonathan S. Coblyn⁴, Michael Weinblatt¹, Nancy Shadick⁵, Nehal N. Mehta³ and Jeremy Sokolove², ¹Division of Rheumatology, Immunology, and Allergy, Brigham & Women's Hospital, Boston, MA, ²Medicine, VA Palo Alto HealthCare System and Stanford University, Palo Alto, CA, ³NHLBI, National Institutes of Health, Bethesda, MD, ⁴Brigham & Women's Hospital, Boston, MA, ⁵Division of Rheumatology, Immunology & Allergy, Brigham & Women's Hospital, Boston, MA
Background/Purpose: High density lipoprotein (HDL) cholesterol efflux capacity measures how well HDL particles remove cholesterol from lipid-laden macrophages, such as those found in atherosclerotic plaques. …
Abstract Number: 1608 • 2015 ACR/ARHP Annual Meeting
Protective Role of the Vitamin D Receptor Apai (rs7975232) Polymorphism Against Subclinical Atherosclerosis in Patients with Rheumatoid Arthritis from Northern Spain
Raquel López-Mejías¹, Fernanda Genre¹, Sara Remuzgo-Martínez¹, Gema Robledo², Begoña Ubilla¹, Veronica Mijares¹, Javier Llorca³, Montserrat Robustillo-Villarino⁴, Alfonso Corrales¹, Carlos González-Juanatey⁵, Jose A. Miranda-Filloy⁶, Trinitario Pina⁷, Ricardo Blanco⁷, Esther Vicente⁸, Juan José Alegre⁹, Cesar Magro¹⁰, Enrique Raya¹¹, Beatriz Tejera¹², Marco A Ramírez Huaranga¹³, Ivan Ferraz-Amaro¹², Santos Castañeda¹⁴, Javier Martín² and Miguel A. Gonzalez-Gay^1,15, ¹Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, Santander, Spain, ²Institute of Parasitology and Biomedicine López-Neyra, IPBLN-CSIC, Granada, Spain, ³Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain, ⁴Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain, ⁵Cardiology Division, Hospital Lucus Augusti, Lugo, Spain, ⁶Rheumatology Division, Hospital Lucus Augusti, Lugo, Spain, ⁷Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ⁸Rheumatology Department, Hospital Universitario la Princesa, IIS-Princesa, Madrid, Spain, ⁹Rheumatology, Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain, ¹⁰Rheumatology Department, Hospital Clínico San Cecilio, Granada, Spain, ¹¹Rheumatology, Hospital Clínico San Cecilio, Granada, Spain, ¹²Rheumatology Division, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, ¹³Rheumatology Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain, ¹⁴Rheumatology, H.U. La Princesa, Madrid, Spain, ¹⁵Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Background/Purpose: Several vitamin D receptor (VDR) polymorphisms have been associated with cardiovascular (CV) and autoimmune diseases. Carotid plaques are surrogate markers of severe atherosclerotic disease.…
Abstract Number: 2200 • 2015 ACR/ARHP Annual Meeting
Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking Clinical Database and Repository Cluster Analysis: Identification of Different Clinical Phenotypes Among Antiphospholipid Antibody-Positive Female Patients
Stephane Zuily¹, Cecilia B. Chighizola², DENIS WAHL¹, Pier Luigi Meroni³ and Doruk Erkan⁴, ¹CHU de Nancy, Vascular Medicine Division and Regional Competence Centre For Rare Vascular And Systemic Autoimmune Diseases; and UMR_S U1116 Research Unit, France, Nancy, France, ²Department of Clinical Sciences and Community Health, University of Milan, Istituto Auxologico Italiano, Cusano Milanino, Italy, ³University of Milan, Department of Clinical Sciences and Community Health, Division of Rheumatology, Gaetano Pini Institute, Milan, Italy, ⁴Barbara Volcker Center for Women & Rheumatic Disease, Hospital for Special Surgery, New York, NY
Background/Purpose: APS ACTION International Clinical Database and Repository was created to study the natural course of persistently antiphospholipid antibodies (aPL)-positive patients ± autoimmune disorders over…
Abstract Number: 3120 • 2015 ACR/ARHP Annual Meeting
The Prevalence, Incidence and Management of Hypertension, Diabetes and Hyperlipidemia in Psoriatic Arthritis, Psoriasis and Rheumatoid Arthritis
Kashif Jafri¹, Christie M. Bartels², Daniel Shin³ and Alexis Ogdie-Beatty⁴, ¹Department of Medicine, University of Pennsylvania, Philadelphia, PA, ²Medicine, Rheumatology, University of Wisconsin School of Medicine and Public Health, Madison, WI, ³University of Pennsylvania, Philadelphia, PA, ⁴Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Psoriasis, psoriatic arthritis (PsA), and rheumatoid arthritis (RA) are associated with an increased risk for cardiovascular disease (CVD). While management of traditional CVD risk…
Abstract Number: 473 • 2015 ACR/ARHP Annual Meeting
Methotrexate, Blood Pressure and Arterial Wave Reflection in Rheumatoid Arthritis
Leena R Baghdadi^1,2,3, Richard J Woodman², E Michael Shanahan⁴ and Arduino A Mangoni³, ¹Department of Family and Community Medicine, King Saud University, Riyadh, Saudi Arabia, ²Flinders Centre for Epidemiology and Biostatistics, Flinders University, Adelaide, Australia, ³Department of Clinical Pharmacology, Flinders University, Adelaide, Australia, ⁴Department of Rheumatology, Flinders University, Adelaide, Australia
Background/Purpose: Methotrexate (MTX) use has been associated with reduced cardiovascular morbidity and mortality in patients with rheumatoid arthritis (RA). Although MTX has anti-inflammatory effects, there…
Abstract Number: 1515 • 2015 ACR/ARHP Annual Meeting
Accounting for Rheumatoid Arthritis in the Determination of 10 Year Cardiovascular Risk
Rupal Chavda and Rochella A. Ostrowski, Rheumatology, Loyola University Medical Center, Maywood, IL
Background/Purpose: Patients with rheumatoid arthritis (RA) carry a higher risk for cardiovascular disease (CVD) independent of traditional risk factors. In this study, we set out…

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