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Abstracts tagged "Cardiovascular disease and systemic sclerosis"

  • Abstract Number: 2689 • ACR/ARHP Annual Meeting 2018

    Association between Small Vessel Disease and Arterial Stiffness in Systemic Sclerosis

    Stergios Soulaidopoulos1, Eleni Pagkopoulou1, Eva Triantafyllidou1, Niki Katsiki2, George D. Kitas3,4, Asterios Karagiannis2, Alexandros Garyfallos1 and Theodoros Dimitroulas1, 1Fourth Department of Internal Medicine, Hippokration University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece, 2Second Department of Propaedeutic Internal Medicine, Hippokration University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece, 3Department of Rheumatology, Dudley Group of Hospitals, NS Foundation Trust, Dudley, United Kingdom, 4Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, United Kingdom

    Background/Purpose: Microangiopathy predominates in the pathophysiology of Systemic Sclerosis (SSc). However, large vessel involvement leading to higher risk for cardiovascular disease in SSc remains unclear.…
  • Abstract Number: 1870 • ACR/ARHP Annual Meeting 2016

    First Pilot Study of an Implantable Loop Recorder (ILR) in Systemic Sclerosis Detects Significant Cardiac Arrhythmias with CMR Abnormalities

    Lesley-Anne Bissell1, Bianca Dumitru1, Giuseppina Abignano1, Bara Erhayiem2, Graham Fent2, Peter Swoboda2, Adam McDiarmid2, John Greenwood2, Francesco Del Galdo1, Jacqueline Andrews1, Sven Plein2, Lee Graham2 and Maya Buch1, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 2Multidisciplinary Cardiovascular Research Centre & The Division of Cardiovascular and Diabetes Research, LIGHT, University of Leeds, Leeds, United Kingdom

    Background/Purpose: SSc-cardiomyopathy associated conduction abnormalities carry a poor prognosis, but their pathogenesis is unclear. Early detection to prevent complications is essential. ILRs are well-established in…
  • Abstract Number: 1890 • ACR/ARHP Annual Meeting 2015

    Subclinical Biventricular Systolic Function Is Impaired in Patients with Systemic Sclerosis with Real Time 3-D Echpcardiography: 1 Year Follow-up Study

    Sule Yavuz1, Taylan Sahin2, Selen Yurdakul2, Neslihan Yilmaz3 and Saide Ertekin4, 1Rheumatology, Istanbul Bilim University, Faculty of Medicine,Department of Rheumatology, Istanbul, Turkey, 2Cardiology, Istanbul Bilim University Dept of Cardiology, Istanbul, Turkey, 3Istanbul Bilim University, Faculty of Medicine, Rheumatology Department, Istanbul, Turkey, 4Cardiology, Istanbul Bilim University, Dept of Cardiology, Istanbul, Turkey

    Background/Purpose: Silent myocardial involvement is associated with poor prognosis in patients with systemic sclerosis (SSc). Here, we aimed to evaluate subclinical left ventricular (LV) and…
  • Abstract Number: 1687 • ACR/ARHP Annual Meeting 2014

    Key Role of Cardiac Biomarkers in the Assessment of Systemic Sclerosis: Contribution of High Sensitivity Cardiac Troponin

    Jerome Avouac1, Christophe Meune2, Camille Gobeaux3, Didier Borderie3, Guillaume Lefevre4, Andre Kahan5 and Yannick Allanore1, 1Paris Descartes University, Rheumatology A Department and INSERM U1016, Cochin Hospital, Paris, France, 2Paris 13 University, University Hospital of Paris-Seine-Saint-Denis, Cardiology Department, Bobigny, France, 3Paris Descartes University, Biochemistry A department, Cochin Hospital, Paris, France, 4Clinical Chemistry and Hormonology Department, Tenon Hospital, paris, France, 5Paris Descartes University, Rheumatology A department, Cochin Hospital, Paris, France

    Background/Purpose: Microangiopathy is a cardinal feature of systemic sclerosis (SSc), which plays a critical role in the development of primary myocardial involvement and pulmonary hypertension,…
  • Abstract Number: 730 • ACR/ARHP Annual Meeting 2014

    Prediction of Cardiac and Vascular Events in Systemic Sclerosis: Input from Endothelin-1 Type a Receptor Antibodies

    Jerome Avouac1, Gabriela Riemekasten2, Christophe Meune3, Barbara Ruiz4 and Yannick Allanore1, 1Paris Descartes University, Rheumatology A Department and INSERM U1016, Cochin Hospital, Paris, France, 2Charité University Hospital and German Rheumatism Research Centre, a Leibniz Institute, Berlin, Germany, 3Paris 13 University, University Hospital of Paris-Seine-Saint-Denis, Cardiology Department, Bobigny, France, 4Paris Descartes University, INSERM U1016, Institut Cochin, Sorbonne Paris Cité, Paris, France

    Background/Purpose: Cardiac and peripheral microvascular alterations are key features of systemic sclerosis (SSc). We have previously reported that angiogenic markers can predict the cardiovascular outcomes…
  • Abstract Number: 1929 • ACR/ARHP Annual Meeting 2014

    Echocardiographic Phenomics for Novel Classification of Cardiac Involvement in Systemic Sclerosis

    Monique Hinchcliff1, Vistasp Daruwalla2, Lauren Beussink-Nelson3, Sofia Podlusky4, Mary A. Carns4, John Varga5 and Sanjiv J. Shah6, 1Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 2Department of Internal Medicine, Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Department of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL, 4Department of Medicine, Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 5Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 6Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose: Traditional studies of systemic sclerosis (SSc) cardiac involvement have examined one or a few echocardiographic (echo) variables; however, cardiac involvement in SSc can be…
  • Abstract Number: 1688 • ACR/ARHP Annual Meeting 2014

    Early Detection of Left Ventricular Morphological, Functional Abnormalities and Myocardial Characteristics in Systemic Sclerosis without Cardiac Symptoms Using Cardiac Magnetic Resonance Imaging: A Preliminary Report

    Kaita Sugiyama1, Hitomi Kobayashi2, Yasuyuki Kobayashi3, Yosuke Nagasawa4, Natsumi Ikumi2, Takamasa Nozaki4, Hirotake Inomata2, Hidetaka Shiraiwa2, Hiromi Karasawa2, Noboru Kitamura4, Mitsuhiro Iwata4, Yoshihiro Matsukawa2 and Masami Takei4, 1Nihon University School of Medicine, Tokyo, Japan, 2Division of Heamatology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 3Radiology, St.Marianna University School of Medicine, Kawasaki, Japan, 4Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan

    Background/Purpose Systemic sclerosis (SSc) is associated with an increased prevalence of cardiac involvement despite often being clinically silent. Cardiac involvement is a major factor in…
  • Abstract Number: 849 • ACR/ARHP Annual Meeting 2012

    The Risk of Cardiovascular Disease in Systemic Sclerosis: A Population-Based Cohort Study

    Ada Man1, Yanyan Zhu2, Yuqing Zhang3, Maureen Dubreuil1, Young Hee Rho3, Christine Peloquin3, Robert W. Simms1 and Hyon K. Choi4, 1Rheumatology, Boston University School of Medicine, Boston, MA, 2Clinical Epidemiology, Boston University School of Medicine, Boston, MA, 3Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 4Section of Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA

    Background/Purpose:   Recent studies show that the prevalence of subclinical atherosclerosis is increased in individuals with systemic sclerosis (SSc).  An accurate understanding of cardiovascular disease…
  • Abstract Number: 702 • ACR/ARHP Annual Meeting 2012

    Arterial Stiffness Is Increased in Systemic Sclerosis: A Cross-Sectional Comparison with Matched Controls

    Gene-Siew Ngian1, Joanne Sahhar2, Ian Wicks3 and Sharon Van Doornum4, 1Department of Medicine (RMH/WH), The University of Melbourne, Parkville, Australia, 2Rheumatology Unit, Monash Medical Centre, Clayton, Australia, 3Rheumatology Unit, Royal Melbourne Hospital, Melbourne, Australia, 4Department of Medicine (RMH/WH), The University of Melbourne, The Royal Melbourne Hospital, Melbourne, Australia

    Background/Purpose: Atherosclerosis may be increased in systemic sclerosis (SSc)1. Increased arterial stiffness is a predictor of cardiovascular and all-cause mortality across a wide range of…

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