Abstracts tagged "Cardiovascular disease and systemic sclerosis"

Abstract Number: 2689 • 2018 ACR/ARHP Annual Meeting
Association between Small Vessel Disease and Arterial Stiffness in Systemic Sclerosis
Stergios Soulaidopoulos¹, Eleni Pagkopoulou¹, Eva Triantafyllidou¹, Niki Katsiki², George D. Kitas^3,4, Asterios Karagiannis², Alexandros Garyfallos¹ and Theodoros Dimitroulas¹, ¹Fourth Department of Internal Medicine, Hippokration University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece, ²Second Department of Propaedeutic Internal Medicine, Hippokration University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece, ³Department of Rheumatology, Dudley Group of Hospitals, NS Foundation Trust, Dudley, United Kingdom, ⁴Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, United Kingdom
Background/Purpose: Microangiopathy predominates in the pathophysiology of Systemic Sclerosis (SSc). However, large vessel involvement leading to higher risk for cardiovascular disease in SSc remains unclear.…
Abstract Number: 1870 • 2016 ACR/ARHP Annual Meeting
First Pilot Study of an Implantable Loop Recorder (ILR) in Systemic Sclerosis Detects Significant Cardiac Arrhythmias with CMR Abnormalities
Lesley-Anne Bissell¹, Bianca Dumitru¹, Giuseppina Abignano¹, Bara Erhayiem², Graham Fent², Peter Swoboda², Adam McDiarmid², John Greenwood², Francesco Del Galdo¹, Jacqueline Andrews¹, Sven Plein², Lee Graham² and Maya Buch¹, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ²Multidisciplinary Cardiovascular Research Centre & The Division of Cardiovascular and Diabetes Research, LIGHT, University of Leeds, Leeds, United Kingdom
Background/Purpose: SSc-cardiomyopathy associated conduction abnormalities carry a poor prognosis, but their pathogenesis is unclear. Early detection to prevent complications is essential. ILRs are well-established in…
Abstract Number: 1890 • 2015 ACR/ARHP Annual Meeting
Subclinical Biventricular Systolic Function Is Impaired in Patients with Systemic Sclerosis with Real Time 3-D Echpcardiography: 1 Year Follow-up Study
Sule Yavuz¹, Taylan Sahin², Selen Yurdakul², Neslihan Yilmaz³ and Saide Ertekin⁴, ¹Rheumatology, Istanbul Bilim University, Faculty of Medicine,Department of Rheumatology, Istanbul, Turkey, ²Cardiology, Istanbul Bilim University Dept of Cardiology, Istanbul, Turkey, ³Istanbul Bilim University, Faculty of Medicine, Rheumatology Department, Istanbul, Turkey, ⁴Cardiology, Istanbul Bilim University, Dept of Cardiology, Istanbul, Turkey
Background/Purpose: Silent myocardial involvement is associated with poor prognosis in patients with systemic sclerosis (SSc). Here, we aimed to evaluate subclinical left ventricular (LV) and…
Abstract Number: 1929 • 2014 ACR/ARHP Annual Meeting
Echocardiographic Phenomics for Novel Classification of Cardiac Involvement in Systemic Sclerosis
Monique Hinchcliff¹, Vistasp Daruwalla², Lauren Beussink-Nelson³, Sofia Podlusky⁴, Mary A. Carns⁴, John Varga⁵ and Sanjiv J. Shah⁶, ¹Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Department of Internal Medicine, Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Department of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Department of Medicine, Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Traditional studies of systemic sclerosis (SSc) cardiac involvement have examined one or a few echocardiographic (echo) variables; however, cardiac involvement in SSc can be…
Abstract Number: 1688 • 2014 ACR/ARHP Annual Meeting
Early Detection of Left Ventricular Morphological, Functional Abnormalities and Myocardial Characteristics in Systemic Sclerosis without Cardiac Symptoms Using Cardiac Magnetic Resonance Imaging: A Preliminary Report
Kaita Sugiyama¹, Hitomi Kobayashi², Yasuyuki Kobayashi³, Yosuke Nagasawa⁴, Natsumi Ikumi², Takamasa Nozaki⁴, Hirotake Inomata², Hidetaka Shiraiwa², Hiromi Karasawa², Noboru Kitamura⁴, Mitsuhiro Iwata⁴, Yoshihiro Matsukawa² and Masami Takei⁴, ¹Nihon University School of Medicine, Tokyo, Japan, ²Division of Heamatology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ³Radiology, St.Marianna University School of Medicine, Kawasaki, Japan, ⁴Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan
Background/Purpose Systemic sclerosis (SSc) is associated with an increased prevalence of cardiac involvement despite often being clinically silent. Cardiac involvement is a major factor in…
Abstract Number: 1687 • 2014 ACR/ARHP Annual Meeting
Key Role of Cardiac Biomarkers in the Assessment of Systemic Sclerosis: Contribution of High Sensitivity Cardiac Troponin
Jerome Avouac¹, Christophe Meune², Camille Gobeaux³, Didier Borderie³, Guillaume Lefevre⁴, Andre Kahan⁵ and Yannick Allanore¹, ¹Paris Descartes University, Rheumatology A Department and INSERM U1016, Cochin Hospital, Paris, France, ²Paris 13 University, University Hospital of Paris-Seine-Saint-Denis, Cardiology Department, Bobigny, France, ³Paris Descartes University, Biochemistry A department, Cochin Hospital, Paris, France, ⁴Clinical Chemistry and Hormonology Department, Tenon Hospital, paris, France, ⁵Paris Descartes University, Rheumatology A department, Cochin Hospital, Paris, France
Background/Purpose: Microangiopathy is a cardinal feature of systemic sclerosis (SSc), which plays a critical role in the development of primary myocardial involvement and pulmonary hypertension,…
Abstract Number: 730 • 2014 ACR/ARHP Annual Meeting
Prediction of Cardiac and Vascular Events in Systemic Sclerosis: Input from Endothelin-1 Type a Receptor Antibodies
Jerome Avouac¹, Gabriela Riemekasten², Christophe Meune³, Barbara Ruiz⁴ and Yannick Allanore¹, ¹Paris Descartes University, Rheumatology A Department and INSERM U1016, Cochin Hospital, Paris, France, ²Charité University Hospital and German Rheumatism Research Centre, a Leibniz Institute, Berlin, Germany, ³Paris 13 University, University Hospital of Paris-Seine-Saint-Denis, Cardiology Department, Bobigny, France, ⁴Paris Descartes University, INSERM U1016, Institut Cochin, Sorbonne Paris Cité, Paris, France
Background/Purpose: Cardiac and peripheral microvascular alterations are key features of systemic sclerosis (SSc). We have previously reported that angiogenic markers can predict the cardiovascular outcomes…
Abstract Number: 849 • 2012 ACR/ARHP Annual Meeting
The Risk of Cardiovascular Disease in Systemic Sclerosis: A Population-Based Cohort Study
Ada Man¹, Yanyan Zhu², Yuqing Zhang³, Maureen Dubreuil¹, Young Hee Rho³, Christine Peloquin³, Robert W. Simms¹ and Hyon K. Choi⁴, ¹Rheumatology, Boston University School of Medicine, Boston, MA, ²Clinical Epidemiology, Boston University School of Medicine, Boston, MA, ³Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ⁴Section of Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA
Background/Purpose: Recent studies show that the prevalence of subclinical atherosclerosis is increased in individuals with systemic sclerosis (SSc). An accurate understanding of cardiovascular disease…
Abstract Number: 702 • 2012 ACR/ARHP Annual Meeting
Arterial Stiffness Is Increased in Systemic Sclerosis: A Cross-Sectional Comparison with Matched Controls
Gene-Siew Ngian¹, Joanne Sahhar², Ian Wicks³ and Sharon Van Doornum⁴, ¹Department of Medicine (RMH/WH), The University of Melbourne, Parkville, Australia, ²Rheumatology Unit, Monash Medical Centre, Clayton, Australia, ³Rheumatology Unit, Royal Melbourne Hospital, Melbourne, Australia, ⁴Department of Medicine (RMH/WH), The University of Melbourne, The Royal Melbourne Hospital, Melbourne, Australia
Background/Purpose: Atherosclerosis may be increased in systemic sclerosis (SSc)1. Increased arterial stiffness is a predictor of cardiovascular and all-cause mortality across a wide range of…

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