Abstracts tagged "Cardiovascular disease and rheumatoid arthritis (RA)"

Abstract Number: 1269 • 2012 ACR/ARHP Annual Meeting
Serum Cytokines Associated with Carotid Atherosclerosis in Rheumatoid Arthritis
Inmaculada del Rincon¹, Roy W. Haas², Daniel H. O'Leary³, Joseph F. Polak³, Daniel F. Battafarano⁴ and Agustin Escalante⁵, ¹Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX, ²Dept. of Medicine-Rheumatology, University of Texas Health Science Center, San Antonio, TX, ³Radiology, Tufts University-Boston Campus, Boston, MA, ⁴Medicine / MCHE-MDR, Brooke Army Medical Ctr, San Antonio, TX, ⁵Dept. of Medicine-Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX
Background/Purpose: The mechanism for the increased cardiovascular morbidity and mortality in rheumatoid arthritis (RA) is incompletely understood. In a previous analysis, we found that both…
Abstract Number: 1247 • 2012 ACR/ARHP Annual Meeting
Delay in Diagnosis of Rheumatoid Arthritis Increases the Cardiovascular Risk
Chan-Bum Choi¹, Yoon-Kyoung Sung², Soo-Kyung Cho², Dae-Hyun Yoo³, Shin-Seok Lee⁴, Jisoo Lee⁵, Jinseok Kim⁶, Hye-Soon Lee⁷, Tae-Hwan Kim³, Bo Young Yoon⁸, Wan-Hee Yoo⁹, Jung-Yoon Choe¹⁰, Sang-Heon Lee¹¹, Seung-Cheol Shim¹², Won-Tae Chung¹³, Seung-Jae Hong¹⁴, Choong Ki Lee¹⁵, Eunmi Koh¹⁶, Jae-Bum Jun³, So-Young Bang⁷, Seong-Kyu Kim¹⁷, Hoon-Suk Cha¹⁶, Jeeseon Shim¹⁸, Sang-Cheol Bae¹⁹ and Korean Observational Study Network for Arthritis (KORONA)²⁰, ¹Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, ²Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ³Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ⁴Dept of Int Med/Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, ⁵Internal Medicine, Ewha Womans University Mokdong Hospital, Seoul, South Korea, ⁶Internal Medicine, Jeju National University Hospital, Jeju, South Korea, ⁷Department of Rheumatology, Hanyang University Guri Hospital, Guri, South Korea, ⁸Inje University Ilsan Paik Hospital, Goyang, South Korea, ⁹Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine, Jeonju, South Korea, ¹⁰Internal Medicine, Catholic university of Daegu School of mediine, Arthritis and autoimmunty research center, Daegu, ¹¹Division of Rheumatology, Department of Internal Medicine,, Konkuk University School of Medicine, Seoul, South Korea, ¹²Rheumatology, Eulji University Hospital, Daejeon, South Korea, ¹³Rheumatology, Dong-A University Hospital, Busan, South Korea, ¹⁴Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, Seoul, South Korea, ¹⁵Internal medicine, school of medicine, Yeungnam University, Daegu, South Korea, ¹⁶Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, ¹⁷Catholic University of Daegu School of Medicine, Daegu, South Korea, ¹⁸Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, ¹⁹Hanyang University Hospital for Rheumatic Disease, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, ²⁰Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul
Background/Purpose: Patients with rheumatoid arthritis (RA) are known to be at increased risk for cardiovascular diseases. Inflammation as well as traditional risk factors contributes to…
Abstract Number: 1248 • 2012 ACR/ARHP Annual Meeting
Accelerated Aging Influences Cardiovascular Disease Risk in Rheumatoid Arthritis
Cynthia S. Crowson¹, Terry M. Therneau¹, John M. Davis III², Veronique L. Roger³, Eric L. Matteson² and Sherine E. Gabriel⁴, ¹Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ²Rheumatology, Mayo Clinic, Rochester, MN, ³Health Sciences Research and Cardiology, Mayo Clinic, Rochester, MN, ⁴Health Sciences Research & Div of Rheumatology, Mayo Clinic, Rochester, MN
Background/Purpose: People with rheumatoid arthritis (RA) suffer an excess burden of cardiovascular disease (CVD), yet standard risk assessments designed for the general population do not…
Abstract Number: 1205 • 2012 ACR/ARHP Annual Meeting
Study of Association of CD40-CD154 Gene Polymorphisms with Disease Susceptibility and Cardiovascular Risk in Spanish Rheumatoid Arthritis Patients
Mercedes García-Bermúdez¹, Carlos González-Juanatey², Alfonso Corrales³, Raquel López-Mejías⁴, Maria Teruel⁵, Jose A. Miranda-Filloy⁶, Santos Castañeda-Sanz⁷, Alejandro Balsa⁸, B. Fernández-Gutierrez⁹, Isidoro González-Álvaro¹⁰, Carmen Gómez-Vaquero¹¹, R. Blanco Alonso¹², Javier Llorca¹³, Javier Martin¹⁴ and Miguel Angel González-Gay⁴, ¹Immunology and Cellular Biology, Instituto de Parasitologia y Biomedicina López-Neyra, IPBLN-CSIC, Granada, Spain, ²Cardiology Division, Hospital Lucus Augusti, Lugo, Spain, ³Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, ⁴Rheumatology, Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, ⁵Immunology, Instituto de Parasitología y Biomedicina López-Neyra, IPBLN-CSIC, Granada, Spain, ⁶Rheumatology, Division of Rheumatology, Hospital Lucus Augusti, Lugo, Spain, ⁷Rheumatology, Hospital Universitario de La Princesa. Madrid. Spain, Madrid, Spain, ⁸Rheumatology, La Paz Hospital. IdiPaz, Madrid, Spain, ⁹Department of Rheumatology, Hospital Clinico San Carlos, Madrid, Spain, ¹⁰Servicio de Reumatología, Reumatología (Hospital Universitario de La Princesa), Madrid, Spain, ¹¹Rheumatology Service, Hospital Universitari de Bellvitge - IDIBELL, Barcelona, Spain, ¹²Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain, ¹³Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), Santander, Spain, ¹⁴Immunology, Instituto de Parasitologia y Biomedicina Lopez-Neyra (IPBLN-CSIC), Granada, Spain
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased cardiovascular (CV) mortality. Since CD40-CD154 binding has direct consequences on inflammation process initiation,…
Abstract Number: 1211 • 2012 ACR/ARHP Annual Meeting
ANTI-Cyclic Citrullinated Protein Antibodies Induce Inflammation and Oxidative Stress in WHITE Blood CELLS of Rheumatoid Arthritis Patients
Chary Lopez-Pedrera¹, Carlos Perez-Sanchez¹, Patricia Ruiz-Limon¹, Mª Angeles Aguirre², Rosario M. Carretero-Prieto¹, Antonio Rodriguez-Ariza³, Nuria Barbarroja¹, Pilar Font¹, Francisco Martinez², Inmaculada Gomez-Gracia², Mª Jose Cuadrado⁴ and Eduardo Collantes-Estevez², ¹Rheumatology Unit, IMIBIC-Reina Sofia University Hospital, Cordoba, Spain, ²Rheumatology, IMIBIC-Reina Sofia Hospital, Cordoba, Spain, ³Oncology Service and Research Unit, IMIBIC-Reina Sofia Hospital, Cordoba, Spain, ⁴Lupus Research Unit, The Rayne Institute, London, United Kingdom
Background/Purpose: Anti-cyclic citrulinated protein antibodies (anti-CCP) are the most specific autoantibody markers in rheumatoid arthritis (RA) patients. However no previous studies have evaluated their role…
Abstract Number: 829 • 2012 ACR/ARHP Annual Meeting
Subcutaneous Nodules Are Significantly Associated with Cardiovascular Events in Patients with Rheumatoid Arthritis: Results From a Very Large US Registry
Prashant Kaushik¹, Susan P. Messing², Jyoti Arora², George Reed³, Katherine C. Saunders⁴, Jeffrey D. Greenberg⁵ and Joel M. Kremer⁶, ¹Department of Medicine, Sratton VAMC, Albany, NY, ²Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY, ³Division of Behavioral and Preventive Medicine, University of Massachusetts Medical School, Worcester, MA, ⁴Corrona, LLC., Southborough, MA, ⁵New York Hospital for Joint Disease, New York, NY, ⁶Albany Medical College and The Center for Rheumatology, Albany, NY
Background/Purpose: Cardiovascular Disease (CVD) is now recognized to be a major comorbidity of patients with rheumatoid arthritis. Predictors of CVD have been shown to include…
Abstract Number: 71 • 2012 ACR/ARHP Annual Meeting
The Association Between Preclinical Markers for Cardiovascular Disease and Rheumatoid Arthritis-Related Autoantibodies in First-Degree Relatives without Rheumatoid Arthritis
Ryan W. Gan¹, Jan M. Hughes-Austin², Kevin D. Deane³, Elaine M. Urbina⁴, Peter K. Gregersen⁵, Michael H. Weisman⁶, V. Michael Holers⁷ and Jill M. Norris¹, ¹Epidemiology, Colorado School of Public Health, Aurora, CO, ²Epidemiology, Colorado School of Public Health / University of Colorado Anschutz Medical Campus, Aurora, CO, ³Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ⁴Preventive Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵Genomics and Human Genetics, Feinstein Institute for Medical Research, Manhasset, NY, ⁶Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁷Rheumatology Division, University of Colorado School of Medicine, Aurora, CO
Background/Purpose: Rheumatoid arthritis (RA) is characterized by systemic inflammation and immune dysregulation, including the presence of autoantibodies and elevated inflammatory markers in subjects with…

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