Abstracts tagged "Cardiovascular disease and rheumatoid arthritis (RA)"

Abstract Number: 2131 • 2015 ACR/ARHP Annual Meeting
Younger Age and Female Gender Are the Main Determinants of Underestimation of Cardiovascular Risk in Rheumatoid Arthritis Patients
Calin Popa^1,2, Alexander Rennings³, Alfons A. den Broeder⁴, Frank H.J. van den Hoogen⁴, Inger L. Meek¹ and Jaap Fransen¹, ¹Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Rheumatology, Bernhoven Hospital, Uden, Netherlands, ³Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ⁴Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands
Background/Purpose: Rheumatoid arthritis (RA) patients have an increased cardiovascular (CV) risk. Current algorithms generally underestimate the risk in these patients [1]. In a meta-analysis, we…
Abstract Number: 1501 • 2015 ACR/ARHP Annual Meeting
Prevalence of Unassessed and Uncontrolled Cardiovascular Disease Risk Factors Among Rheumatoid Arthritis Patients in an Academic Rheumatology Practice
Darcy S. Majka¹, Eric M. Ruderman², Ji Young Lee³, Elisha Friesema⁴ and Stephen D. Persell⁴, ¹Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Medicine, Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴General Internal Medicine, Northwestern University Feinberg School of Medicine, chicago, IL
Background/Purpose: Cardiovascular disease (CVD) is the leading cause of death in individuals with rheumatoid arthritis (RA). Patients with RA are at 1.5-2.0-fold increased risk of…
Abstract Number: 2630 • 2015 ACR/ARHP Annual Meeting
Rheumatoid Arthritis Patients with Carotid Plaque: 10-Year Follow-up
Raymundo Vera-Pineda¹, Alberto Cardenas-de La Garza², Dionicio A. Galarza-Delgado², Jose Ramon Azpiri-Lopez³, Iris J. Colunga-Pedraza², Jorge Munoz De Hoyos², Griselda Serna-Peña⁴, Brenda B Tovar-Jasso², Mario Alberto Garza-Elizondo² and Gerardo Ornelas⁵, ¹Cardiology., Hospital Universitario, UANL., Monterrey, Mexico, ²Rheumatology, Hospital Universitario, UANL., Monterrey, Mexico, ³Cardiology, Hospital Universitario, UANL., Monterrey, Mexico, ⁴Internal Medicine, Hospital Universitario, UANL., Monterrey, Mexico, ⁵Radiology, Hospital Universitario, UANL., Monterrey, Mexico
Background/Purpose: The main cause of mortality in patients with rheumatoid arthritis (RA) is atherosclerotic cardiovascular disease (ASCVD). RA patients have a 10-year decrease in life…
Abstract Number: 1540 • 2015 ACR/ARHP Annual Meeting
Cardiovascular Risk Management in Rheumatoid Arthritis Patients
Calin Popa¹, Elke.E.A. Arts¹, Inger L. Meek¹, Frank H.J. van den Hoogen² and Jaap Fransen¹, ¹Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands
Background/Purpose: Rheumatoid arthritis (RA) patients have been previously shown to have a higher cardiovascular (CV) burden as compared to the general population. The CV risk…
Abstract Number: 2636 • 2015 ACR/ARHP Annual Meeting
Comparison of Arterial Health in Patients with Rheumatoid Arthritis to a Population-Based Cohort
Caroline Ball¹, John M. Davis III², Cynthia S. Crowson³, Iftikhar Kullo⁴, Eric L. Matteson⁵ and Rekha Mankad⁶, ¹Internal Medicine, Mayo Clinic, Rochester, MN, ²Division of Rheumatology, Mayo Clinic, Rochester, MN, ³Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, ⁵Division of Rheumatology, Department of Internal Medicine and Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ⁶Cardiovascular Diseases, Mayo Clinic, Rochester, MN
Title: Comparison of Arterial Health in Patients with Rheumatoid Arthritis to a Population-based Cohort Background/Purpose: Patients with rheumatoid arthritis (RA) have increased risk of cardiovascular…
Abstract Number: 1542 • 2015 ACR/ARHP Annual Meeting
Arterial Vascular Events in Hispanics from Puerto Rico with Rheumatoid Arthritis
Ariana González-Meléndez¹, Ruth Fred-Jimenez², Mariangelí Arroyo-Ávila², Leyda Díaz-Correa², Naydi Pérez-Ríos³, Noelia Rodríguez-Pérez², Grissel Ríos² and Luis M. Vilá², ¹School of Medicine, Ponce Health Sciences University, Ponce, PR, ²Department of Medicine, Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, San Juan, PR, ³Puerto Rico Clinical and Translational Research Consortium, University of Puerto Rico Medical Sciences Campus, San Juan, PR
Background/Purpose: Arterial vascular events have a great impact in the morbidity and mortality of rheumatoid arthritis (RA). Traditional and nontraditional risk factors for arterial vascular…
Abstract Number: 2677 • 2015 ACR/ARHP Annual Meeting
Targeting Biomarkers of Nitric Oxide and Endothelial Dysfunction in Patients with Rheumatoid Arthritis
Ankita Satpute¹, Stanley Hazen^2,3, WH Wilson Tang³ and M. Elaine Husni⁴, ¹Case Western Reserve University School of Medicine, Cleveland, OH, ²Cell Biology, Cell Biology, Cleveland Clinic Foundation, Cleveland, OH, ³Cardiology, Cardiology, Cleveland Clinic Foundation, Cleveland, OH, ⁴Rheumatology Dept A50, Cleveland Clinic Foundation, Cleveland, OH
Background/Purpose: Numerous studies have reported increased cardiovascular morbidity and mortality in rheumatoid arthritis (RA) patients that cannot be explained by traditional risk factors. In a…
Abstract Number: 1548 • 2015 ACR/ARHP Annual Meeting
Comparison of 5 Cardiovascular Risk Calculators in a Hispanic Rheumatoid Arthritis Cohort
Alberto Cardenas-de La Garza¹, Raymundo Vera-Pineda², Dionicio A. Galarza-Delgado¹, Jose Ramon Azpiri-Lopez³, Iris J. Colunga-Pedraza¹, Griselda Serna-Peña⁴ and Mario Alberto Garza-Elizondo¹, ¹Rheumatology, Hospital Universitario, UANL., Monterrey, Mexico, ²Cardiology., Hospital Universitario, UANL., Monterrey, Mexico, ³Cardiology, Hospital Universitario, UANL., Monterrey, Mexico, ⁴Internal Medicine, Hospital Universitario, UANL., Monterrey, Mexico
Background/Purpose: Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in RA. Management and stratification of ASCVD in RA patients is still a matter…
Abstract Number: 3257 • 2015 ACR/ARHP Annual Meeting
The Link Between DAS28 and the Short-Term Risk of Acute Coronary Syndrome in RA, and Its Driving Factors
Lotta Ljung^1,2, Thomas Frisell³ and Johan Askling^3,4, ¹Department of Medicine, Solna, Clinical epidemiology unit, Karolinska Institutet, Stockholm, Sweden, ²Department for Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Sweden, ³Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, ⁴Rheumatology Unit, Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden
Background/Purpose: The extent to which a short-term effect of the disease activity adds to the over-risk of coronary events in patients with Rheumatoid Arthritis (RA)…
Abstract Number: 1565 • 2015 ACR/ARHP Annual Meeting
High Disease Activity over Time and Persistent Inflammation Are Associated with Increased Risk of Cardiovascular Disease in Patients with Early Rheumatoid Arthritis
Emil Rydell^1,2, Christina Book^1,2, Jan-Åke Nilsson^1,2, Minna Willim^1,2, Lennart T.H. Jacobsson^1,3 and Carl Turesson^1,4, ¹Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, ²Department of Rheumatology, Skåne University Hospital, Malmö, Sweden, ³Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden, ⁴Lund University, Rheumatology, Dept. of Clinical Sciences,, Malmö, Sweden
Background/Purpose: Rheumatoid arthritis (RA) is associated with an increased rate of cardiovascular (CV) disease. Systemic inflammation has been implicated as a key factor behind CV…
Abstract Number: 1572 • 2015 ACR/ARHP Annual Meeting
Plasma Apolipoprotein B48 Levels in Patients with Rheumatoid Arthritis: Evaluating Novel Cardiovascular Risk Factors
Deborah van Breukelen-van der Stoep¹, Derkjen van Zeben¹, Marijke de Vries², Boudewijn Klop², Noelle van der Meulen², Gert Jan van de Geijn³, Hans Janssen³, Pedro Valdivielso⁴, José Rioja⁴, José Ramirez-Bollero⁴, Mieke Hazes⁵, Erwin Birnie^6,7 and Manuel Castro Cabezas⁸, ¹Department of Rheumatology, Sint Franciscus Gasthuis, Rotterdam, Netherlands, ²Department of Internal Medicine, Sint Franciscus Gasthuis, Rotterdam, Netherlands, ³Department of Clinical Chemistry, Sint Franciscus Gasthuis, Rotterdam, Netherlands, ⁴Department of Internal Medicine and Dermatology, Hospital Virgen de la Victoria, Malaga, Spain, ⁵Department of Rheumatology, Erasmus Medical Centre Rotterdam, Rotterdam, Netherlands, ⁶Statistics and Education, Sint Franciscus Gasthuis, Rotterdam, Netherlands, ⁷Insitute of Health Policy and Management, Erasmus University, Rotterdam, Netherlands, ⁸Department of Internal Medicine, Sint Francicscus Gasthuis, Rotterdam, Netherlands
Background/Purpose: Chylomicrons, with apolipoprotein (apo) B48 as a structural protein, induce leukocyte and complement activation and contribute to atherosclerosis. ApoB48 is higher in conditions associated…
Abstract Number: 1575 • 2015 ACR/ARHP Annual Meeting
Serum Vascular Cell Adhesion Molecule-1 (VCAM-1) Levels Are Associated with Vascular Dysfunction and Increased Cardiovascular Risk in an Animal Model and Patients with Rheumatoid Arthritis
Ruth Davies¹, Daniela Iacono², Lauren A. Jordan¹, Jessica O Williams¹, Charlotte Rawlings¹, Derek Lang³, Anwen S. Williams¹ and Ernest H. Choy¹, ¹Cardiff University, Institute of Infection and Immunity, Tenovus Building, University Hospital of Wales, Cardiff, United Kingdom, ²Department of Clinical and Experimental Medicine. Rheumatology Section. Second University of Naples, Naples, Italy, ³Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine, Cardiff, United Kingdom
Background/Purpose: Mortality is increased in Rheumatoid arthritis (RA) patients mainly due to cardiovascular (CV) disease; however the biologic mechanisms are unknown. Increased CV risk in…
Abstract Number: 1591 • 2015 ACR/ARHP Annual Meeting
A Low Adiponectin Level in Rheumatoid Arthritis Is Associated with Coronary Artery Disease
Jon Roger Eidet¹, Ida G. Fostad², Kelly J. Shields³, Torstein Lyberg¹, Tor Paaske Utheim¹, Anita Kåss⁴, Knut Mikkelsen⁵, Terje Veel⁶, Kjell Saatvedt⁷, Morten Wang Fagerland⁸, Matthew Liang⁹ and Ivana Hollan⁵, ¹Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway, ²Department of Oral Biology, Faculty of Dentistry, University of Oslo, Oslo, Norway, ³Medicine, Lupus Center of Excellence / Allegheny Health Network, Pittsburgh, PA, ⁴Rheumatology, Betanien Hospital, Skien, Norway, ⁵Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway, ⁶Department of Cardiac Surgery, Feiring Heart Clinic, Feiring, Norway, ⁷Department of Cardiothoracic Surgery, Oslo University Hospital, Oslo, Norway, ⁸Department of Biostatistics, Oslo University Hospital, Oslo, Norway, ⁹Department of Rheumatology, Brigham and Women’ s Hospital, Boston, Boston, MA
Background/Purpose: Adipokines exert pleiotropic actions, including immunoregulatory and matrix degrading effects. There is evidence of adipokine involvement in the pathogenesis of cardiovascular (CV) disease as…
Abstract Number: 1592 • 2015 ACR/ARHP Annual Meeting
Sex Differences in Cardiovascular Risk Factors and Event Rates in Patients with Rheumatoid Arthritis – Data from 13 Rheumatology Centers
Silvia Rollefstad¹, Eirik Ikdahl¹, Cynthia S. Crowson², Sherine Gabriel³, George D. Kitas⁴, Piet L van Riel⁵, Anne Grete Semb⁶ and ATACC-RA, ¹Preventive Cardio-Rheuma Clinic, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Health Sciences Research, Mayo Clinic, Rochester, MN, ³Division of Rheumatology; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴The Dudley Group of Hospitals NHS Foundation Trust, Dudley, United Kingdom, ⁵Scientific Institute for Quality of Healthcare, Radboud University Medical Center, Nijmegen, Netherlands, ⁶Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: Patients with rheumatoid arthritis (RA) have an excess risk of cardiovascular disease (CVD). There is a clear female to male preponderance of RA. In…
Abstract Number: 1593 • 2015 ACR/ARHP Annual Meeting
Telomere Length and Cardiovascular Risk in Rheumatoid Arthritis
Michelle J. Ormseth¹, Joseph F. Solus², Annette M. Oeser³, Aihua Bian⁴, Tebeb Gebretsadik⁴, Ayumi Shintani⁵, Paolo Raggi⁶ and C Michael Stein⁵, ¹Department of Medicine, Division of Rheumatology, Vanderbilt University, Nashville, TN, ²Clinical Pharmacology, Vanderbilt University, Nashville, TN, ³Medicine, Vanderbilt University, Nashville, TN, ⁴Biostatistics, Vanderbilt University, Nashville, TN, ⁵Vanderbilt University, Nashville, TN, ⁶Emory University, Atlanta, GA
Background/Purpose: Telomeres protect against DNA damage and shorten with each cell division; their length may be a marker of cardiovascular and overall biological aging. Patients…

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