Abstracts tagged "cardiovascular disease and genetic disorders"

Abstract Number: 228 • 2014 ACR/ARHP Annual Meeting
Is Adult Hypophosphatasia a Cardiovascular Risk Factor?
Leyre Riancho-Zarrabeitia¹, Maria T. García-Unzueta², Alfonso Corrales³, Juan Gómez-Gerique² and José A. Riancho⁴, ¹Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, ²Biochemistry, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, ³Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, ⁴Internal Medicine, Hospital Universitario Marqués de Valdecilla. IDIVAL. University of Cantabria, Santander, Spain
Background/Purpose Mild forms of adult hypophosphatasia may have subtle manifestations, and may go unrecognized. The aim of this study was to get a better knowledge of its clinical spectrum. Methods We performed a computerized search of low total alkaline phosphatase among laboratory records. The diagnosis of hypophosphatasia was confirmed by measuring serum pyridoxal phosphate (PLP) and bone alkaline phosphatase. Carotid ultrasonography was performed in patients and controls with a MyLab 70…

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