Abstracts tagged "capillaroscopy and systemic sclerosis"

Abstract Number: 808 • 2018 ACR/ARHP Annual Meeting
Mean Number of Nailfold Capillaries Is Associated with Disease Activity at 6 Months Follow-up in Systemic Sclerosis Patients
Ana Maria Gheorghiu¹, Raida Oneata², Alexandra Radu¹, Anca Briceag¹, Cristiana Draganescu¹, Cristina Vrancianu¹, Stefania Magda³, Tudor Constantinescu⁴, Alina Soare⁵, Rucsandra Dobrota⁶, Ioan Ancuta⁷, Claudia Ciofu⁷, Liviu Macovei⁷, Mihaela Milicescu⁷, Mariana Sasu⁷, Alexandra Enuica⁸, Octavian Linte⁸, Gheorghe Stan⁸, Brindus Comanescu⁸, Teodor Necsoiu⁸, Mihai Bojinca¹, Victor Stoica⁷ and Carina Mihai^7,9, ¹Internal Medicine and Rheumatology, Carol Davila University of Medicine and Pharmacy, Cantacuzino Hospital, Bucharest, Romania, ²Internal Medicine and Rheumatology Department, Carol Davila University of Medicine and Pharmacy, Cantacuzino Hospital, Bucharest, Romania, ³Cardiology Department, University Emergency Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, ⁴Marius Nasta National Pneumology Institute, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, ⁵Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany, ⁶Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, ⁷Carol Davila University of Medicine and Pharmacy, Cantacuzino Hospital, Bucharest, Romania, ⁸Optoelectronica, Bucharest, Romania, ⁹Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland
Background/Purpose: Nailfold capillaroscopy (NFC) is essential in the evaluation and classification of systemic sclerosis (SSc). The mean number of capillaries is considered a promising tool…
Abstract Number: 2660 • 2017 ACR/ARHP Annual Meeting
Endothelin-1 and Interleukin-6 Serum Levels Are Associated with More Severe Vasculopathy in Patients  with Systemic Sclerosis
Ana Maria Gheorghiu¹, Roxana Sfrent-Cornateanu², Daciana Marta³, Raida Oneata⁴, Mihai Bojinca⁴, Stefania Magda⁵, Tudor Constantinescu⁶, Rucsandra Dobrota⁷, Alina Soare⁸, Liviu Macovei¹, Victor Stoica⁴, Constantin Bara² and Carina Mihai⁹, ¹Carol Davila University of Medicine and Pharmacy,Internal Medicine and Rheumatology Department ,,Dr.I.Cantacuzino'' Clinical Hospital, Bucharest, Romania, ²Immunology and Physiopathology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, ³Victor Babes National Institute of Research and Development, Bucharest, Romania, ⁴Carol Davila University of Medicine and Pharmacy, Internal Medicine and Rheumatology Department, Cantacuzino Clinical Hospital, Bucharest, Romania, ⁵Cardiology Department, University Emergency Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, ⁶Marius Nasta National Pneumology Institute, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, ⁷Department of Rheumatology, Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁸Department of Internal Medicine 3 – Rheumatology and Immunology, Universitätsklinikum Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Germany, ⁹Internal Medicine and Rheumatology Dept., Cantacuzino Clinical Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Background/Purpose: Systemic sclerosis (SSc) is a severe connective tissue disease characterized by vascular and fibrotic changes in the skin and various internal organs. Pathogenesis of…
Abstract Number: 2987 • 2015 ACR/ARHP Annual Meeting
An EULAR Study Group Pilot Study on Reliability of Simple� Capillaroscopic Definitions to Describe Capillary Morphology in Rheumatic Diseases
Vanessa Smith¹, Sam Beeckman², Ariane L. Herrick³, Saskia Decuman⁴, Ellen Deschepper⁵, Filip De Keyser⁶, Oliver Distler⁷, Ivan Foeldvari⁸, Francesca Ingegnoli⁹, Ulf Müller-Ladner¹⁰, Valeria Riccieri¹¹, Gabriela Riemekasten¹², Alberto Sulli¹³, Alexandre E. Voskuyl¹⁴ and Maurizio Cutolo¹³, ¹Department of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium, ²Department of Rheumatology, Ghent University, Ghent University Hospital,, Ghent, Belgium, ³Centre for Musculoskeletal Research, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom, ⁴Department of Rheumatology, UGent, Ghent, Belgium, ⁵Biostatistics Unit, Biostatistics Unit, Ghent University, Ghent, Belgium, ⁶Rheumatology, Ghent University Hospital, Ghent, Belgium, ⁷Research of Systemic Autoimmune Diseases, Division of Rheumatology, University Hospital Zurich, 8952 Schlieren, Switzerland, ⁸Hamburger Zentrum für Kinder-und Jugendrheumatologie, Hamburg, Germany, ⁹Division of Rheumatology, Istituto Gaetano Pini, Department of Clinical Sciences & Community Health, University of Milano, Milano, Italy, ¹⁰Internal Medicine and Rheumatology, Justus-Liebig-University of Giessen, Kerckhoff-Klinik, Bad Nauheim, Germany, ¹¹Cattedra di Reumatologia, Dip Clinica e Terapia Medica, Sapienza Università di Roma, Roma, Italy, ¹²Clinic of Rheumatology, University of Luebeck, Lübeck, Germany, ¹³Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, IRCCS A.O.U. San Martino-IST, University of Genova, Genoa, Italy, Genoa, Italy, ¹⁴Rheumatology, Amsterdam Rheumatology and immunology Center, location VU University medical center, Amsterdam, Netherlands
Background/Purpose: The EULAR study group on Microcirculation in Rheumatic Diseases (RD) aims to build an international network of centres of excellence to facilitate collaboration and…
Abstract Number: 2982 • 2015 ACR/ARHP Annual Meeting
Blood Perfusion in Different Skin Areas of Hands in Primary Raynaud’s Phenomenon and Systemic Sclerosis Patients
Alberto Sulli¹, Barbara Ruaro¹, Amelia Chiara Trombetta¹, Vanessa Smith², Carmen Pizzorni¹, Sabrina Paolino¹ and Maurizio Cutolo¹, ¹Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, IRCCS A.O.U. San Martino-IST, University of Genova, Genoa, Italy, Genoa, Italy, ²Department of Rheumatology, Ghent University Hospital, Ghent University, Ghent, Belgium
Background/Purpose: Peripheral blood perfusion is reduced in patients affected by both primary (PRP) or secondary Raynaud’s phenomenon (SRP) (1-2). The objective of this study was…
Abstract Number: 2963 • 2015 ACR/ARHP Annual Meeting
Correlations Between Microvasculature Changes and Angiogenic Factors in Systemic Sclerosis – Data from a Single Center Registry
Radim Becvar¹, Simona Skacelova², Jiri Stork³, Hana Hulejová⁴, Ivana Putova⁵, Michal Tomcik⁶ and Marie Jachymova⁷, ¹Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, ²Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Prague, Czech Republic, ³Clinic of Dermatology and Venerology, Prague, Czech Republic, ⁴Institute of Rheumatology, Department of Rheumatology of the First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, ⁵Institute of Rheumatology and Department of Rheumatology of the 1st Faculty of Medicine, Charles University, Prague 2, Czech Republic, ⁶Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Prague, Czech Republic, ⁷Second Internal Clinic – Clinic of Cardiology and Angiology, General University Hospital,, Prague, Czech Republic
Background/Purpose: Histopathological hallmarks of systemic sclerosis (SSc) are perivascular infiltrates and a reduced capillary density, which precede the excessive accumulation of extracellular matrix components in…
Abstract Number: 1909 • 2015 ACR/ARHP Annual Meeting
Nailfold Capillaroscopic Assessment and Vascular Biomarkers in Systemic Sclerosis: Low CD40L Levels in Patients with Late Scleroderma Patterns
Yasemin Yalcinkaya¹, Suzan Cinar², Sevil Kamali³, Ozlem Pehlivan⁴, Lale Ocal¹, Gunnur Deniz² and Murat Inanc³, ¹Istanbul Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul, Turkey, ²Department of Immunology, Istanbul University, Institute of Experimental Medicine (DETAE), Istanbul, Turkey, ³Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ⁴Istanbul Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul, Turkey
Background/Purpose: To determine the relationship between vascular biomarkers reflecting the vascular injury and neoangiogenesis with nailfold capillaroscopic changes in systemic sclerosis (SSc). Methods: Seventy-two SSc…
Abstract Number: 2598 • 2013 ACR/ARHP Annual Meeting
Timing and Outcome Of Transition From Primary To Secondary Raynaud’s Phenomenon: A Capillaroscopic Based Study
Alberto Sulli¹, Giorgia Ferrari², Elena Bernero², Carmen Pizzorni², Vanessa Smith³, Barbara Ruaro² and Maurizio Cutolo⁴, ¹Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, ²Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, ³Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, ⁴Internal medicine, Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy
Background/Purpose: Raynaud's phenomenon (RP) is classified as primary (PRP) or secondary (SRP) depending on its association with an underlying disease (1,2). PRP can evolve to…
Abstract Number: 1483 • 2012 ACR/ARHP Annual Meeting
Predictors of Digital Ulcers in Systemic Sclerosis: Correlation Between Clinical and Hemodynamic Features, Capillaroscopy, Endothelium Dysfunction and Angiogenesis Biomarkers
Ivone Silva¹, Isabel Almeida¹, António Marinho² and Carlos Vasconcelos³, ¹Raynaud Clinics, Porto, Portugal, ²Unidade de Imunologia Clínica, Porto, Portugal, ³Imunologia Clinica - M Interna, Hospital Geral Santo Antonio, Porto, Portugal
Background/Purpose: Digital Ulcers (DU) are a major disabling complication of Systemic Sclerosis (SSc) interfering with personal and professional life of our patients. The aim of…
Abstract Number: 1511 • 2012 ACR/ARHP Annual Meeting
Low Circulating Endothelial Progenitor Cell Levels and High VEGF Serum Levels Are Associated with the Late Nailfold Capillaroscopic Pattern in Systemic Sclerosis
Jerome Avouac¹, Maeva Vallucci², Vanessa Smith³, Barbara Ruiz², Alberto Sulli⁴, Carmen Pizzorni⁵, Gilles Chiocchia⁶, Maurizio Cutolo⁷ and Yannick Allanore⁸, ¹Paris Descartes University, Rheumatology A department, Cochin Hospital, Paris, France, ²Paris Descartes University, INSERM U1016, Institut Cochin, Sorbonne Paris Cité, Paris, France, ³Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, ⁴Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, ⁵Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, ⁶Immunology and Hematology Department, Institut Cochin - INSERM U1016 - CNRS (UMR 8104), Paris, France, ⁷Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genova, Italy, ⁸Rheumatology, Paris Descartes University, Rheumatology A department, Cochin Hospital, Paris, France
Background/Purpose: To assess whether nailfold videocapillaroscopy (NVC) changes are associated with peripheral blood or serum levels of angiogenic biomarkers in systemic sclerosis (SSc). Methods: Endothelial…