Abstracts tagged "C4 gene"

Abstract Number: 149 • Pediatric Rheumatology Symposium 2020
Low C4 Copy Number of Total C4 Gene, C4B Gene and C4BL Gene in Children with Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)
Agnieszka Kalinowski ¹, Justin Lee ², Haley Hedlin ², Reenal Pattini ², Hanna Ollila ², Emmanuel Mignot ¹, Douglas Levinson ², Susan Swedo ³, Tanya Murphy ⁴, Avis Chan ⁵, Margo Thienemann ¹, Alexander Urban ² and Jennifer Frankovich⁶, ¹Stanford University School of Medicine, Palo Alto, California, ²Stanford University, Palo Alto, California, ³National Institute of Mental Health, Bethesda, Maryland, ⁴University of South Florida, Tampa, Florida, ⁵Stanford University School of Medicine, Palo Alto, ⁶Stanford
Background/Purpose: Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) is characterized by sudden-onset OCD and additional neuropsychiatric symptoms. Imaging studies point to inflammation in the basal ganglia as…