Abstracts tagged "BTK and rheumatoid arthritis (RA)"

Abstract Number: 37 • 2018 ACR/ARHP Annual Meeting
Discovery of DWP213388, a Potent ITK and BTK Dual Target Inhibitor with Excellent Efficacy, As a Treatment for Autoimmune Diseases
Jae Hun Jung¹, Deokki Eom¹, Seong-Uk Jeon¹, Yong Dae Shin¹, Wolyoung Kim¹, Jaehyun Jung¹, Qingri Li¹, Hyaejung Hyun¹ and Joon Seok Park², ¹Daewoong pharmaceutical, Yongin-si, Korea, Republic of (South), ²Daewoong pharmaceutical, Seoul, Korea, Republic of (South)
Background/Purpose: Interleukin-2-inducible T-cell Kinase (ITK) and Bruton's tyrosine kinase (BTK) are critical for B cells and T cells activation, and dysregulation of this process has…

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Abstracts tagged "BTK and rheumatoid arthritis (RA)"

Discovery of DWP213388, a Potent ITK and BTK Dual Target Inhibitor with Excellent Efficacy, As a Treatment for Autoimmune Diseases