Abstracts tagged "bone marrow and interferons"

Abstract Number: 2111 • 2018 ACR/ARHP Annual Meeting
Ifnβ Affects Osteogenesis-Adipogenesis Axis in SLE Bone Marrow
Lin Gao, Mary O'Connell, Jennifer Anolik and R. John Looney, Medicine- Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY
Background/Purpose: SLE patients are especially vulnerable to corticosteroid induced avascular necrosis. While it is appreciated that multiple factors contribute to AVN, the bone-fat axis in…
Abstract Number: 1836 • 2016 ACR/ARHP Annual Meeting
SLE Bone Marrow Contains Factors That Promote Type I Interferon Activation
Nida Meednu¹, Anna Bird², Jennifer Barnard², Mariana Kaplan³ and Jennifer H. Anolik², ¹Medicine- Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, ²University of Rochester Medical Center, Rochester, NY, ³NIAMS/NIH, Bethesda, MD
Background/Purpose: SLE is characterized by the inappropriate activation of type I Interferon (IFN) and increases in apoptosis and NETosis by neutrophils, which in combination with…