ACR Meeting Abstracts

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Abstracts tagged "bone marrow and interferons"

  • Abstract Number: 2111 • 2018 ACR/ARHP Annual Meeting

    Ifnβ Affects Osteogenesis-Adipogenesis Axis in SLE Bone Marrow

    Lin Gao, Mary O'Connell, Jennifer Anolik and R. John Looney, Medicine- Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY

    Background/Purpose: SLE patients are especially vulnerable to corticosteroid induced avascular necrosis. While it is appreciated that multiple factors contribute to AVN, the bone-fat axis in…
  • Abstract Number: 1836 • 2016 ACR/ARHP Annual Meeting

    SLE Bone Marrow Contains Factors That Promote Type I Interferon Activation

    Nida Meednu1, Anna Bird2, Jennifer Barnard2, Mariana Kaplan3 and Jennifer H. Anolik2, 1Medicine- Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, 2University of Rochester Medical Center, Rochester, NY, 3NIAMS/NIH, Bethesda, MD

    Background/Purpose: SLE is characterized by the inappropriate activation of type I Interferon (IFN) and increases in apoptosis and NETosis by neutrophils, which in combination with…
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