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Abstracts tagged "bone disease and treatment"

  • Abstract Number: 1939 • ACR/ARHP Annual Meeting 2017

    Dipyridamole, an Ent-1 Adenosine Transporter Inhibitor, Reverts De Osteoclastic Phenotype Induced By Tenofovir

    Francisco Miguel Conesa-Buendia1, Patricia Llamas2, Tuere Wilder3, Patricia Atencio4, Alfonso Cabello5, Miguel Gorgolas4, Bruce Cronstein6, Raquel Largo7, Gabriel Herrero-Beaumont7 and Aranzazu Mediero8, 1Bone and Joint Research Unit, IIS-Fundacion Jimenez Diaz- UAM, Madrid, Spain, 2Bone and Joint Research Unit, IIS-Fundacion Jimenez Díaz-UAM, Madrid, Spain, 3Department of Medicine, Division of Rheumatology, NYU School of Medicine, New York, NY, 4Internal Medicine Department, IIS-Fundacion Jimenez Diaz-UAM, Madrid, Spain, 5Internal MEdicine Department, IIS-Fundacion Jimenez Diaz-UAM, Madrid, Spain, 6Rheumatology, New York University School of Medicine, Division of Rheumatology, New York, NY, 7Bone and Joint Research Unit, IIS-Fundación Jiménez Díaz UAM, Madrid, Spain, 8Bone and Joint Research Unit, Fundación Jiménez Díaz-UAM, Madrid, Spain

    Background/Purpose: Adenosine, generated from the catabolism of adenine nucleotides, modulates cell function by interacting with specific cell-surface receptors (A1R, A2AR, A2BR, A3R). Inhibition of osteoclast…

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