Abstracts tagged "Bone density"

Abstract Number: 1998 • 2012 ACR/ARHP Annual Meeting
Relationship Between Changes in Bone Mineral Density and Incidence of Fracture with 6 Years of Denosumab Treatment
Michael A. Bolognese¹, Paul D. Miller², Jean-Yves Reginster³, Nathalie Franchimont⁴, Gerolamo Bianchi⁵, Roland Chapurlat⁶, Federico G. Hawkins⁷, David L. Kendler⁸, Beatriz Oliveri⁹, Jose R. Zanchetta¹⁰, Nadia Daizadeh⁴, Andrea Wang⁴, Rachel B. Wagman⁴ and Socrates Papapoulos¹¹, ¹Bethesda Health Research Center, Bethesda, MD, ²University of Colorado Health Sciences Center and Colorado Center for Bone Research, Lakewood, CO, ³Department of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium, ⁴Amgen Inc., Thousand Oaks, CA, ⁵LELICOMAR - Div Reumatologia, Azienda Sanitaria Genovese, Genoa, Italy, ⁶Hôpital Edouard Herriot, Lyon, France, ⁷Hospital Universitario, Madrid, Spain, ⁸University of British Columbia, Vancouver, BC, Canada, ⁹Laboratorio Enfermedades Metabólicas Oseas, Hospital de Clínicas, INIGEM UBA-CONICET, Buenos Aires, Argentina, ¹⁰Instituto de Investigaciones Metabólicas and University of Salvador, Buenos Aires, Argentina, ¹¹Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: During the first 3 years of denosumab treatment in FREEDOM, there were continued increases in bone mineral density (BMD) and a robust reduction in…
Abstract Number: 1970 • 2012 ACR/ARHP Annual Meeting
Utility of Spine Bone Mineral Density in Fracture Prediction within the Fracture Risk Assessment Tool (FRAX)
Tristan Blackburn¹, Diantha Howard² and Edward S. Leib³, ¹Rheumatology, Fletcher Allen Health Care, University of Vermont College of Medicine, Burlington, VT, ²Medicine, Vermont Center for Clinical and Translational Science, Burlington, VT, ³Medicine, Fletcher Allen Health Care, University of Vermont College of Medicine, Burlington, VT
Background/Purpose: Predicting which individuals are at risk to experience a fracture and modify that risk is important in preventative health. The WHO’s Fracture Risk Assesment…
Abstract Number: 1958 • 2012 ACR/ARHP Annual Meeting
Bone Mineral Density in Lupus Erythematosus Women One Year After Rituximab Therapy
Claudia Mendoza-Pinto¹, Mario Garcia-Carrasco¹, Mario Jiménez-Hernández¹, Alma Rodríguez-Gallegos², Socorro Méndez-Martínez¹ and Aurelio Lopez-Colombo³, ¹Systemic Autoimmune Disease, HGR 36 CMN Manuel Ávila Camacho, Instituto Mexicano del Seguro Social, Puebla, Mexico, ²Laboratorios Clínicos de Puebla, Puebla, Mexico, ³Research Departament, Delegación Estatal, Instituto Mexicano del Seguro Social, Puebla, Mexico
Background/Purpose: Low bone mineral density (BMD) and osteoporosis may be significant complications in patients with systemic lupus erythematosus (SLE). Recent studies have shown that biologic therapy could…
Abstract Number: 1557 • 2012 ACR/ARHP Annual Meeting
What Percentage of Postmenopausal Women Younger Than Age 65 Years Have Low Bone Mineral Density At a Family Health Center?
Marvin Vaishnani¹ and Feyrouz T. Al-Ashkar², ¹Rheumatic and Immunologic diseases, Cleveland Clinic,Lorain Institute, Lorain, OH, ²Rheumatic and Immunologic Diseases, Cleveland Clinic,Lorain Institute, Lorain, OH
Background/Purpose: Many younger women, < 65 years of age may have low bone mineral density (BMD) that remains undetected in clinical practice due to following…
Abstract Number: 1226 • 2012 ACR/ARHP Annual Meeting
Transition Time to Osteoporosis in Patients with Rheumatoid Arthritis
Jiwon Hwang¹, Joong Kyong Ahn², Ji Young Chai³, Hoon-Suk Cha¹, Jaejoon Lee¹ and Eunmi Koh¹, ¹Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, ²Department of Medicine, Kangbuk Samsung hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea, ³Division of Rheumatology, Jesang Hospital, Seongnam-si Gyeonggi-do, South Korea
Background/Purpose: Rheumatoid arthritis (RA) is an independent risk factor for osteoporosis. Although bone mineral density (BMD) testing is routinely performed in patients with RA, the…
Abstract Number: 2583 • 2012 ACR/ARHP Annual Meeting
Bone Structure and Perfusion Quantification of Bone Marrow Edema and Pannus Tissue Areas in the Wrist of Patients with RA
Jose R. Teruel Antolin¹, Andrew J. Burghardt², Julien Rivoire¹, Waraporn Srikhum¹, Susan M. Noworolski³, Thomas M. Link¹, John B. Imboden⁴ and Xiaojuan Li⁵, ¹Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, ²Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ³Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, ⁴Department of Medicine, Division of Rheumatology, UCSF, San Francisco, CA, ⁵Department of Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA
Background/Purpose: Bone marrow edema (BME) has been suggested as a strong predictor for erosive progression in RA joints, however, no previous studies examined the bone…
Abstract Number: 1117 • 2012 ACR/ARHP Annual Meeting
Association Between Hip Bone Marrow Lesions (BMLs) and Bone Mineral Density: A Cross-Sectional and Longitudinal Population-Based Study
Harbeer Ahedi¹, Dawn Dore¹, Leigh Blizzard², Flavia Cicuttini³ and Graeme Jones⁴, ¹Musculoskeletal Unit, Menzies Research institute Tasmania, University of Tasmania, Hobart, 7000, Australia, ²Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, ³Department of Epidemiology and Preventive Medicine, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, 3004, Australia, ⁴Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia
Background/Purpose: Bone marrow lesions (BMLs) have been identified one of the key pathologic features in knee osteoarthritis (OA) 1. However, there is limited data on…
Abstract Number: 2408 • 2012 ACR/ARHP Annual Meeting
Effects of Ground and Joint Reaction Force Exercise On Bone Mineral Density in Postmenopausal Women: A Meta-Analysis of Randomized Controlled Trials
George A. Kelley¹, Kristi S. Kelley¹ and Wendy M. Kohrt², ¹Biostatistics, West Virginia University, Morgantown, WV, ²Geriatric Medicine, University of Colorado @ Denver, Aurora, CO
Background/Purpose: Previous randomized controlled trials have led to conflicting findings regarding the effects of ground and/or joint reaction force exercise on femoral neck (FN) and…
Abstract Number: 1007 • 2012 ACR/ARHP Annual Meeting
High Resolution Peripheral Quantitative CT Detects Marked Differences in Metacarpal Head and Shaft and Ultra-Ultra-Distal Radius Bone Volumetric Density and Microstructure in Early Rheumatoid Arthritis
Lynne M. Feehan¹, Helen R. Buie², Linda C. Li¹, Kamran Shojania³, Cheryl Barnabe⁴ and Heather A. McKay⁵, ¹Physical Therapy, Arthritis Research Centre of Canada and University of British Columbia, Vancouver, BC, Canada, ²Mechanical Engineering, University of Calgary, Calgary, AB, Canada, ³Rheumatology, University of British Columbia, Vancouver, BC, Canada, ⁴Medicine, Community Health Sciences, University of Calgary, Calgary, AB, Canada, ⁵Family Practice and Orthoepedics, University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Despite improvements in clinical management of rheumatoid arthritis (RA), many with early disease are still at high risk for developing periarticular erosions and osteopenia,…
Abstract Number: 2415 • 2012 ACR/ARHP Annual Meeting
Does Interleukin-6 Mediate the Relation Between Estrogen and Bone? an Epidemiologic Approach in the Framingham Osteoporosis Study
Robert R. McLean¹, Xiaochun Zhang², Andrea D. Coviello³, Joao D.T. Fontes⁴, L. Adrienne Cupples⁵, Douglas P. Kiel⁶ and Marian T. Hannan¹, ¹Institute for Aging Research, Hebrew SeniorLife & Harvard Medical School, Boston, MA, ²Institute for Aging Research, Hebrew Senior Life, Boston, MA, ³Boston University School of Medicine, Boston, MA, ⁴Framingham Heart Study and Boston University, Framingham, MA, ⁵Department of Biostatistics, Boston University School of Public Health, Boston, MA, ⁶Institute for Aging Research, Hebrew SeniorLife, Dept. of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
Background/Purpose: Laboratory and animal studies suggest that lower sex hormone levels promote production and activity of pro-inflammatory cytokines that trigger bone resorption. This paradigm is…
Abstract Number: 1010 • 2012 ACR/ARHP Annual Meeting
Bone Loss Before Clinical Onset of Rheumatoid Arthritis o Subjects with Anti-Citrullinated Protein Antibodies
Stephanie Finzel¹, Veronika Lang², Arnd Kleyer¹, Juergen Rech³, Bernhard Manger¹, Elizabeth Araujo¹, Axel J. Hueber⁴, Ulrike Harre⁵ and Georg Schett¹, ¹Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ²Dept. of Medicine, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Germany, ³Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany, ⁴Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ⁵Institute for Clinical Immunology, Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany
Background/Purpose: Anti-citrullinated protein antibodies (ACPA) are a major risk factor for rapid disease progression in rheumatoid arthritis (RA). We have recently shown that ACPA directly…
Abstract Number: 2013 • 2012 ACR/ARHP Annual Meeting
Cross-Sectional and Longitudinal comparison of Bone Mass Status, Using pQCT, in a Large Cohort of Juvenile Idiopathic Arthritis and Juvenile Onset Systemic Lupus Erythematosus Patients
Fernanda Falcini¹, Stefano Stagi², Loredana Cavalli³, Giulia Carnesecchi⁴, Federico Bertini⁴, Laura Masi³, Marco Matucci-Cerinic⁵ and Maria Luisa Brandi³, ¹Department of Biomedicine, Division of Rheumatology AOUC, Excellence Centre for Research, Florence, Italy, ²Pediatric Unit,, Mugello's Hospital, Borgo San Lorenzo, Firenze, Italy, ³Department of Internal Medicine, Endocrinology Unit, University of Florence, Firenze, Italy, ⁴Department of Internal Medicine, Rheumatology Section, University of Florence, Florence, Italy, ⁵Medicine, Univ Florence, Firenze, Italy
Background/Purpose: A small number of prospective data have been published on the use of pQCT in large groups of pts with JIA and JSLE. Moreover,…
Abstract Number: 923 • 2012 ACR/ARHP Annual Meeting
Low Bone Mineral Density and Higher Parathyroid Hormone Levels As Independent Factors to All-Cause Mortality in Community-Dwelling Older Adults: the São Paulo Ageing & Health Study (SPAH)
Diogo S. Domiciano¹, Luana G. Machado², Jaqueline B. Lopes², Camille P. Figueiredo², Valéria Caparbo³, Liliam Takayama², Eloisa Bonfa⁴ and Rosa M.R. Pereira³, ¹Rheumatology, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil, ²Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ³Rheumatology, University of São Paulo, São Paulo, Brazil, ⁴Rheumatology Division, University of São Paulo, Sao Paulo, Brazil
Background/Purpose: Previous studies have shown a relationship between osteoporosis and increased risk of death. Moreover, secondary hyperparathyroidism has been linked to mortality amongst frail older…
Abstract Number: 1979 • 2012 ACR/ARHP Annual Meeting
Care Gap in the Treatment of Patients with High Risk for Fractures in a Single Canadian Academic Center
Arthur N. Lau¹, Michael Branch², Robert Bensen³, Jonathan D. Adachi⁴, Alexandra Papaioannou⁵, William Wong-Pack⁶ and William G. Bensen⁷, ¹Rheumatology and Clinical Epidemiology, Division of Rheumatology, McMaster University, Hamilton, ON, Canada, ²CEO, Inovex, Oakville, ON, Canada, ³Rheumatology Health Team, Dr. Bensen's Rheumatology Clinic, Hamilton, ON, Canada, ⁴St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, ⁵Geriatric Medicine, McMaster University, Hamilton, ON, Canada, ⁶Department Of Nuclear Medicine, Hamilton, ON, Canada, ⁷Department of Medicine, Division of Rheumatology, St. Joseph's Hospital and McMaster University, Hamilton, ON, Canada
Background/Purpose: A number of clinical prediction tools are available to stratify patients into low, moderate and high risk for fractures in future. These tools are…
Abstract Number: 444 • 2012 ACR/ARHP Annual Meeting
Tocilizumab Improves Bone Mineral Density Compared with Abatacept in Patients with TNF Blockers-Resistant Active Rheumatoid Arthritis. an Open Label Randomized Controlled Trial
Kensuke Kume¹, Kanzo Amano¹, Susumu Yamada¹, Kazuhiko Hatta², Kuniki Amano³, Noriko Kuwaba⁴ and Hiroyuki Ohta⁵, ¹Rheumatology, Hiroshima Clinic, Hiroshima, Japan, ²Rheumatology, Hatta Clinic, Kure, Japan, ³Rheumatology, Sky Clinic, Hiroshima, Japan, ⁴Medical Research, Sanki Clinical Link, Hiroshima, Japan, ⁵Medical Research, hiroshima clinic, Hiroshima, Japan
Background/Purpose: To compare the effect of tocilizumab(TCZ) plus methotrexate (MTX), with the effect of abatacept(ABT) plus MTX on bone mineral density(BMD) in TNF blockers resistant…

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