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Abstracts tagged "Bone density"

  • Abstract Number: 2126 • ACR Convergence 2024

    Analysis of the Evolution of Bone Mineral Density in the Spanish Population: Results of the OsteoSER Study

    Carmen Gomez Vaquero1, Marta Domínguez-Álvaro2, Daniel Seoane-Mato3, Pilar Peris4, Santos Castañeda5, Eduardo Kanterewicz Binstock6, Ramon Mazzucchelli7, Luis Arboleya8, Miguel Bernad9, Antonio Alvarez-Cienfuegos10, Blanca Correa11, Luis-Maria Jimenez-Liñan12, Carmen Mateo-Pascual13, Mª Mercedes Molina del Rio14, Mercedes Retamal-Ortiz15, Aida Fatima Lopez-Laguna16, Ruth Molera-Valero17, Sara Alvar-Pariente18, Antonio Pascual19, Adolfo Arias-Senso20, Nuria Perez-Gutierrez21, Soledad Garcia-Frias22, David Bouza-Alvarez23, Susana Sostres24, Daniel Suarez-Hernandez25, Ana Zamora-Casal26, Cristina Garcia-Ramirez27 and Enrique González-Dávila28, and OsteoSER Project Collaborative Group, 1Hospital Universitari de Bellvitge, 08907 L'Hospitalet, Catalonia, Spain, 2Sociedad Española de Reumatología, Madrid, Spain, 3Sociedad Española de Reumatología, Madrid, Madrid, Spain, 4Rheumatology Department, Hospital Clínic de Barcelona, Barcelona, Spain, 5Hospital Universitario de la Princesa, Madrid, Spain, 6Hospital Universitari de Vic (Consorci Hospitalari de Vic), Barcelona, Spain, 7Hospital Universitario Fundacion Alcorcon, Madrid, Spain, 8Hospital Universitario Central de Asturias, Oviedo, Spain, 9Hospital Universitario La Paz, Madrid, Spain, 10Conselleria de Sanitat/Hospital de la Vega Baja, Orihuela, Comunidad Valenciana, Spain, 11Clínica Sanz y Correa, A Coruña, Spain, 12Hospital Don Benito-Villanueva, Don Benito, Spain, 13Centro de Salud Fuencarral, distrito Fuencarral-El Pardo, Madrid, Spain, 14Centro de Atención Primaria Viladecans Montbaig, Sant Climent de Llobregat, Spain, 15Centro de Salud Don Benito Oeste, Don Benito, Spain, 16Centro de Salud El Molar, El Molar, Spain, 17Centro de Salud Orihuela 1-El Rabaloche, Orihuela, Spain, 18Centro de Salud Malpica, Malpica, Spain, 19Centro de salud Ronda-Norte y Ronda-Sur Santa Bárbara, Ronda, Spain, 20Centro de Salud de Santa Amalia, Santa Amalia, Spain, 21Centro de Atención Primaria Ramona Via i Pros, El Prat de Llobregat, Spain, 22Centro de Salud de Cortes de la Frontera, Cortes de la Frontera, Spain, 23Centro de Salud Elviña Mesoiro, A Coruña, Spain, 24Centro de Atención Primaria Cap 17 de setembre, El Prat de Llobregat, Spain, 25Centro de Salud de Benejuzar, Benezujar, Spain, 26Centro de Salud Os Mallos, A Coruña, Spain, 27Centro de Salud Ronda-Sur Santa Bárbara, Ronda, Spain, 28Departamento de Matemáticas, Estadística e Investigación Operativa, Universidad La Laguna, San Cristobal de La Laguna, Spain

    Background/Purpose: The bone mineral density (BMD) reference data for the Spanish population comes from the study Multicentre Research Project on Osteoporosis (MPRO), concluded in 1989.Our…
  • Abstract Number: 2127 • ACR Convergence 2024

    Relationship Between Serum Uric Acid and Trabecular Bone Score (TBS) in Healthy Population

    Isabella Silvestre Ignarro1, Gabriela Tieme Ochikubo2, Liliam Takayama3, Valeria de falco Caparbo2, Camille Pinto Figueiredo2, Marcos Rafael Nogueira Cavalcanti1, Angelita Gomes De Souza1, Isabela Judith Martins Bensenor1, Ricardo Fuller1 and Diogo Domiciano4, 1Bone Metabolism Laboratory, Division of Rheumatology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil, 2Bone Metabolism Laboratory, Division of Rheumatology, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, Brazil, São Paulo, SP, Brazil, 3Division of Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, São Paulo, SP, Brazil, 4Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, SP, Brazil

    Background/Purpose: Serum uric acid (UA) has been postulated to play a role against bone loss due to antioxidant mechanisms. Some studies have shown association between…
  • Abstract Number: 2129 • ACR Convergence 2024

    Fracture Risk Assessment Tool (FRAX®) Scores Predict Mortality in Community-Dwelling Elderlies

    Thiago Quadrante Freitas1, Leonardo Olalla2, Luana Machado3, Camille Figueiredo3, Liliam Takayama4, Valeria Caparbo3, Ricardo Oliveira5, Diogo Domiciano1 and Rosa M R Pereira3, 1Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, SP, Brazil, 2Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Quito, Ecuador, 3Division of Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR., São Paulo, SP, Brazil, 4Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, SP, Brazil, 5RDO DIAGNÓSTICOS MÉDICOS, São Paulo, SP, Brazil

    Background/Purpose: The World Health Organization Fracture Risk Assessment Tool (FRAX®) was developed to estimate the 10-year absolute probability of osteoporotic fractures among the general population.…
  • Abstract Number: 2133 • ACR Convergence 2024

    Unveiling the Association Between Low-Density Lipoprotein Cholesterol Lowering and Fracture Risk Among Patients with Hyperlipidaemia in a Population-Based Cohort Study: The Lower, the Better

    Zeqin Wen1, Yilun Wang1, Xiaoxiao Li2, Yuqing Zhang3, Junqing Xie4, Houchen Lyu5, Changjun Li2, Jie Wei6, Guanghua Lei7 and Chao Zeng8, 1Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China (People's Republic), 2Central South University, Changsha, China (People's Republic), 3Massachusetts General Hospital, Quincy, MA, 4University of Oxford, Oxford, United Kingdom, 5Central South University, Beijing, China, 6Department of Orthopaedics, Xiangya Hospital, Central South University; Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China (People's Republic), 7Department of Orthopaedics, Xiangya Hospital, Central South University; Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China (People's Republic), 8Department of Orthopaedics, Xiangya Hospital, Central South University; Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China (People's Republic)

    Background/Purpose: High low-density lipoprotein cholesterol (LDL-C) is a major risk factor for fracture; however, whether LDL-C lowering induced by statins is associated with decreased fracture…
  • Abstract Number: 0027 • ACR Convergence 2024

    Cation Channel TRPC1 Regulates Mesenchymal Stem Cell Differentiation and Bone Formation

    Jyoti Yadav1, Shivmurat Yadav2, Jeremy Houser1, Marta Onopuik3, Leonidas Tsiokas3 and Mary Beth Humphrey1, 1University of Oklahoma College of Medicine, Oklahoma City, OK, 2University of Oklahoma Health Sciences Center, Oklahoma City, OK, 3University of Oklahoma College of Medicine, Oklahoma City

    Background/Purpose: Transient receptor potential canonical 1 (TRPC1), a non-selective cation channel, is characterized by its high permeability to calcium ions (Ca2+), a vital second messenger…
  • Abstract Number: 2136 • ACR Convergence 2024

    Distal Radius Correlation with Femur and Lumbar Spine T-scores: A Comprehensive Analysis

    Monder Lafi1, Hamzah Amin2, Muhammed Aqib Khan3 and Marwan Bukhari4, 1LANCASTER UNIVERSITY, Liverpool, United Kingdom, 2Lancaster University, Lancaster, United Kingdom, 3Lancaster Medical School, Lancaster, United Kingdom, 4University Hospitals of Morecambe bay NHS foundation trust, Lancaster, United Kingdom

    Background/Purpose: Osteoporosis, defined by the WHO as a BMD reduction of 2.5 standard deviations below that of a young healthy adult, is a major public…
  • Abstract Number: 0030 • ACR Convergence 2024

    The Impact of Treadmill Exercise on Various Stages of Osteoarthritis Progression in a Murine Osteoarthritis Model

    Mengcun Chen1, Mingshu Cui2, Yangmei Yang3 and Bin Wang1, 1Thomas Jefferson University, Philadelphia, PA, 2Thomas Jefferson University, Philadelpha, 3Thomas Jefferson University, Philadephia

    Background/Purpose: Evidence supports the benefits of exercise on joint health and its protective effects against osteoarthritis (OA) progression [Allen J, A&R, 2010]. However, most animal…
  • Abstract Number: 2141 • ACR Convergence 2024

    Glucocorticoid Therapy-Associated Bone Fractures Are Associated with Osteoporosis Underscreening in Patients with Rheumatoid Arthritis

    Marlene Marte Furment1 and Andras Perl2, 1SUNY Upstate Medical University, Syracuse, NY, 2SUNY, Syracuse, NY

    Background/Purpose: The majority of bone loss happens within 6 months of glucocorticoid treatment. Per the 2022 American College of Rheumatology (ACR) Glucocorticoid-Induced Osteoporosis Guidelines it…
  • Abstract Number: 0415 • ACR Convergence 2024

    Prevalence and Risk Factors of Low Bone Mineral Density in Children with Juvenile Idiopathic Arthritis

    narendra bagri, Sushain Kalsotra, vandana jain, Manisha Jana, Maroof Ahmed Khan, Yashdeep Gupta and Sumit Kumar Das, All India Institute of Medical Sciences, New Delhi, Delhi, India

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatological disease in children less than 16 years of age. Various factors have been suggested…
  • Abstract Number: 2142 • ACR Convergence 2024

    Comparison of Bone Mineral Density at the Distal Radius, Hip, and Lumbar Spine in Female Patients Undergoing Surgery for Proximal Femur or Distal Radius Fractures: Implications for Osteoporosis Diagnosis

    KEN NAKASEKO, Department of Orthopaedic Surgery and Rheumatology, Kuwana City Medical Center, Kuwana Mie, Japan

    Background/Purpose: Osteoporosis is often diagnosed based on bone mineral density (BMD) measurements at the hip or lumbar spine. However, our previous study reported that 38%…
  • Abstract Number: 1029 • ACR Convergence 2024

    An Analysis of Osteoporosis Screening in Males vs. Females Across Lehigh Valley Health Network

    Benjamin Wolff1, Ryan Bigelsen2, Kathryn Zaffiri2, Susan Kim3 and Philip Dunn4, 1Lehigh Valley Health Network, Macungie, PA, 2Lehigh Valley Health Network, Allentown, PA, 3Lehigh Valley Hospital Network, Allentown, PA, 4Lehigh Valley Health Network, Emmaus, PA

    Background/Purpose: Osteoporosis is a widely recognized disease of the bone where bone mineral density is decreased leading to increased risk for fracture. Bone mineral density…
  • Abstract Number: 2143 • ACR Convergence 2024

    Analysis of Effectiveness and Safety of Romosozumab in Patients with Very High Risk of Fracture in a Spanish Population

    Marina soledad Moreno Garcia1, Roxana González Mazario2, yedra uson Rodriguez3, Erardo meriño Ibarra4, Emilio Giner5, Juan Carlos Cobeta García6, Marilia Arce Benavente7, maria Dolores Fábregas canales8, Julia Ullier Bellmunt3, Giuliano Boselli3, pilar martinez Valles7, Jorge Juan Fragío Gil9, carlos Vazquez Galeano7 and Ana Turrion Nieves10, 1hospital Miguel Servet . Zaragoza, Zaragoza, Aragon, Spain, 2Hospital General de Valencia, Valencia, Comunidad Valenciana, Spain, 3hospital miguel servet, zaragoza, Aragon, Spain, 4Hospital San Jorge Huesca, zaragoza, 5Hospital Royo Villanova, Teruel, Spain, 6Hospital Ernest Lluch, zaragoza, 7hospital miguel servet, Zaragoza, 8Hospital de Barbastro, Huesca, Spain, 9Hospital General Universitario, Valencia, Comunidad Valenciana, Spain, 10Rheumatology Department, Hospital Universitario Virgen de la Vega, Salamanca, Spain

    Background/Purpose: Excluding clinical trials, there is limited evidence on the effect of 12 months of romosozumab treatment on increasing bone mineral density (BMD) in real-world…
  • Abstract Number: 1066 • ACR Convergence 2024

    Development of a Pharmacy-Led Intervention to Improve Osteoporosis Screening in VA Community-Based Outpatient Clinics

    Krista Topalsky1, Lee Arphai2, Mary Ellen Amos2, Amanda Mertz2, Christopher Blum3, Timothy Godbey2, Lori Leonard2, Maya Mattar4, Elizabeth Cable2 and Robert Wenzell2, 1University Hospitals/ Case Western Reserve University, Shaker Heights, OH, 2Cleveland VA Medical Center, Cleveland, OH, 3Cleveland VA Medical Center, Cleveland, 4Louis Stokes VA medical Center, Mayfield Heights, OH

    Background/Purpose: Osteoporosis is a major public health concern in the United States, leading to significant morbidity, mortality, and increased economic burden. Fractures are projected to…
  • Abstract Number: 2226 • ACR Convergence 2024

    Site-specific Differences in the Association of Non-vertebral Major Osteoporotic Fractures and Rheumatoid Arthritis

    John Chen1, Malini Chandra2, Laura Carbone3, John Schousboe4, Elisha Garcia2 and Joan Lo2, 1Kaiser Permanente Oakland Medical Center, Oakland, CA, 2Kaiser Permanente, Oakland, CA, 3Augusta University, Augusta, GA, 4University of Minnesota, Minneapolis, MN

    Background/Purpose: Rheumatoid arthritis (RA) and osteoporosis are both chronic, potentially debilitating conditions that frequently co-occur, affecting millions of people annually. Among those with osteoporosis, RA…
  • Abstract Number: 1084 • ACR Convergence 2024

    Osteoporosis and Osteopenia Diagnosed by Dual-Energy X-Ray Absorptiometry Are Not Increased in Patients with Gout

    Karla Miller1, grant Cannon1, Kyle Register2, Nadia Grant2 and Naomi Schlesinger2, 1University of Utah and Salt Lake City VA, Salt Lake City, UT, 2University of Utah, Salt Lake City, UT

    Background/Purpose: Controversy exists surrounding the association of gout with osteoporosis diagnosis or incident fragility fractures.  Dual-Energy X-Ray Absorptiometry (DXA) scan is the gold standard for…
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