ACR Meeting Abstracts

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Abstracts tagged "body composition"

  • Abstract Number: 0388 • ACR Convergence 2024

    The Association Between Body Composition and Disease and Treatment Outcomes in Patients with Juvenile Idiopathic Arthritis: Results from the CAPRI Registry

    Samantha Morin1, KAREN BEATTIE2, Roxana Bolaria3, Tania Cellucci4, Gaelle Chedeville5, Amieleena Chhabra6, Paul Dancey7, Tommy Gerschman8, Liane Heale9, Julie Herrington2, Adam Huber10, Mehul Jariwala11, Jean-Philippe Proulx-Gauthier12, Dax Rumsey13, Heinrike Schmeling14, Jaime Guzman15 and Michelle Batthish4, and CAPRI Registry Investigators, 1McMaster University, Hamilton, Canada, 2McMaster University, Hamilton, ON, Canada, 3Victoria Arthritis Center, Victoria, BC, Canada, 4McMaster Children's Hospital, Hamilton, ON, Canada, 5The Montreal Children's Hospital, Montreal, QC, Canada, 6University of British Columbia, Penticton, BC, Canada, 7Memorial University, St. John's, Canada, 8University of British Columbia - Vancouver, North Vancouver, BC, Canada, 9McMaster University, Oakville, ON, Canada, 10IWK Health Centre, Halifax, NS, Canada, 11Jim Pattison Children's Hospital, Saskatoon, Canada, 12CHU de Quebec - Universite Laval, Quebec, QC, Canada, 13University of Alberta, Edmonton, AB, Canada, 14University of Calgary, Calgary, AB, Canada, 15University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada

    Background/Purpose: Recent evidence has linked abnormal body weight, underweight or obesity, with poor disease outcomes in adults with inflammatory arthritis. Yet, little is known about…
  • Abstract Number: 0560 • ACR Convergence 2024

    Association Between a Self-Report Screening Tool for Sarcopenia (SARC-F) and Disease Activity, Muscle Strength and Muscle Power Measures, Patient-Reported Outcomes and Body Composition in Patients with Spondyloarthritides

    Iuliia Kononenko1, Marius Bedei2, Bjoern Buehring3, Xenofon Baraliakos4 and Uta Kiltz5, 1Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Germany, Bochum, Germany, 2Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Germany, Herne, Germany, 3Bergisches Rheuma-Zentrum, Wuppertal, Germany, 4Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 5Rheumazentrum Ruhrgebiet Herne, Ruhr-University, D-44649 Herne, Germany

    Background/Purpose: The SARC-F is a self-report screening tool for sarcopenia (Sar) used to identify individuals at risk for poor functional outcomes [1]. The aim of this study was…
  • Abstract Number: 0598 • ACR Convergence 2024

    Cardio-metabolic Effects of Apremilast in Patients with Psoriatic Arthritis: A Prospective Cohort Study

    Eva van Geel1, Romy Hansildaar2, Fatih Çoban1, Bas Dijkshoorn1, Maaike Heslinga1, Reinhard Bos3, Mies Korteweg1, Arno Van Kuijk1 and Michael Nurmohamed4, 1Amsterdam Rheumatology and immunology Center, Amsterdam, Netherlands, 2Amsterdam Rheumatology and immunology Center location Reade, Amsterdam, Netherlands, 3Medical Center Leeuwarden, Leeuwarden, Netherlands, 4Reade and Amsterdam UMC, Kortenhoef, Netherlands

    Background/Purpose: Psoriatic arthritis (PsA) is associated with metabolic and cardiovascular disease. Studies have suggested that treatment with apremilast is associated with weight loss and other…
  • Abstract Number: 0992 • ACR Convergence 2024

    Visceral Adipose Tissue Measured by DXA Predicts Metabolic Syndrome in Low-Income Community-Dwelling Elderly: Insights from the São Paulo Ageing & Health (SPAH) Study

    Gabriel Vansuita Valente1, Luana Machado1, Andre Franco2, Valeria Caparbo1, Liliam Takayama3, Alan Lins Fernandes1, Camille Figueiredo1, Rosa M R Pereira1 and Diogo Domiciano2, 1Division of Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR., São Paulo, SP, Brazil, 2Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, SP, Brazil, 3Division of Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, São Paulo, SP, Brazil

    Background/Purpose: To establish optimal cutoffs for visceral adipose tissue (VAT) to predict cardiometabolic risk in a low-income elderly Brazilian cohort, utilizing dual-energy X-ray absorptiometry (DXA)…
  • Abstract Number: 1192 • ACR Convergence 2024

    Relationship Between Measures of Fat Mass and Knee Osteoarthritis Incidence: The Multicenter Osteoarthritis (MOST) Study

    Kristine Godziuk1, Sarah Tilley2, mike LaValley3, Douglas Kiel4, Michael Nevitt5, C.E. Lewis6, James Torner7 and Tuhina Neogi2, 1University of Alberta, Edmonton, AB, Canada, 2Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 3Boston University School of Public Health, Arlington, MA, 4Hebrew SeniorLife and Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, 5UCSF, Orinda, CA, 6University of Alabama at Birmingham, Birmingham, AL, 7University of Iowa, Iowa City

    Background/Purpose: Obesity [defined by body mass index (BMI) ≥30 kg/m2] is an established risk factor for incident radiographic knee OA (ROA). However, the relative contributions…
  • Abstract Number: 1348 • ACR Convergence 2024

    Analysis of Body Composition in Patients with Moderate-Severe Rheumatoid Arthritis Treated with Anti-TNF Drugs

    Aimara García-Studer1, Fernando Ortiz-Márquez1, Paula Borregón-Garrido1, Arkaitz Mucientes-Ruiz1, Sara Manrique-Arija1 and Natalia Mena Vázquez2, 1Biomedical Research Institute of Malaga (IBIMA)-Bionand Platform, Department of Rheumatology, Regional University Hospital of Malaga, Malaga, Spain, 2IBIMA, Málaga, Andalucia, Spain

    Background/Purpose: Previous studies have described alterations in fat and lean mass in patients with RA, but the effect of treatments on body composition remains unclear.…
  • Abstract Number: 2070 • ACR Convergence 2024

    Increased Circulating Levels of Fatty Acid-binding Proteins as a Potential Biomarker of Disease Damage in Inflammatory Myopathies Patients

    Margherita Giannini1, Anne-Laure Charles2, Julien Blaess3, Rose-Marie Javier4, Bernard Geny5 and Alain Meyer6, 1UR3072, Physiology Department, University Hospital of Strasbourg, Strasbourg, France, 2UR3072, University of Strasbourg, Strasbourg, France, 3Physiology Department, University Hospital of Strasbourg, STRASBOURG, France, 4Rheumatology Department, University Hospital of Strasbourg, STRASBOURG, France, 5UR3072, Physiology Department, University Hospital of StrasbourgUniversity Hospital of Strasbourg, STRASBOURG, France, 6UR3072, Physiology Department, Rheumatology Department, University Hospital of Strasbourg, Strasbourg, France

    Background/Purpose: In inflammatory myopathies (IM), although several treatments effectively control disease activity, a high proportion of patients display sustained disability (damage). Damage might be reversed…
  • Abstract Number: 0294 • ACR Convergence 2023

    Tofacitinib Treatment in Rheumatoid Arthritis Is Associated with Increased Lower Limb Muscle Volume: The Rheumatoid Arthritis and Muscle (RAMUS) Study

    Joshua L Bennett1, Kieren G Hollingsworth2, Arthur Pratt3, Maha Egail3, Catherine Feeney4, Valeria Di Leo4, Robert W Taylor4, Richard Dodds5, Amy E Anderson3, Avan Aihie Sayer5 and John Isaacs6, 1Immunity and Inflammation Theme, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle upon Tyne, United Kingdom, 2Innovation Methodology and Application Theme, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom, 3Immunity and Inflammation Theme, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom, 4Wellcome Centre for Mitochondrial Research, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom, 5AGE Research Group, NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals NHS Foundation Trust and Newcastle University, Newcastle upon Tyne, United Kingdom, 6Translational and Clinical Research Institute, Newcastle University and Musculoskeletal Unit, Newcastle Hospitals, Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom

    Background/Purpose: Approximately 1 in 4 people with RA have sarcopenia, defined as generalised loss of skeletal muscle (SKM) strength and mass, resulting in an increased…
  • Abstract Number: 0334 • ACR Convergence 2023

    Association of a Self-Report Screening Tool for Sarcopenia (SARC-F) with Functional Status Outcomes in Systemic Lupus Erythematosus

    Sarah Lieber1, Yvonne Shea2, Deanna Jannat-Khah2, John Carrino2, M. Carrington Reid3 and Lisa Mandl1, 1Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 2Hospital for Special Surgery, New York, NY, 3Weill Cornell Medicine, New York, NY

    Background/Purpose: Sarcopenia, i.e., loss of skeletal muscle mass and strength, has been associated with multiple adverse health outcomes, including mortality. Although limited data suggest that…
  • Abstract Number: 0540 • ACR Convergence 2023

    The Impact of Baseline BMI and Physical Activity on Upadacitinib Treatment Response: A Post Hoc Analysis of Patients with Ankylosing Spondylitis from the SELECT-AXIS 2 Study

    Angela Crowley1, Lori Siegel1, Pendleton Wickersham2, Heather Jones3, Dan Webster4, Anna Shmagel5, Ana Biljan6, Uta Kiltz7 and Philip Helliwell8, 1Illinois Bone and Joint Institute, Gurnee and Hinsdale, IL, 2Methodist Hospital, Baptist Medical Center and CHRISTUS Santa Rosa Hospital - Westover Hills, San Antonio, TX, 3AbbVie, Inc., Mettawa, IL, 4AbbVie, Inc., Libertyville, IL, 5AbbVie, Inc., Long Grove, IL, 6AbbVie, Inc., Buffalo Grove, IL, 7Rheumazentrum Ruhrgebiet, Herne, Germany, 8University of Leeds, Leeds, United Kingdom

    Background/Purpose: In patients (pts) with AS, higher BMI has been linked to higher disease activity1. However, given that BMI can be a poor indicator of…
  • Abstract Number: 2100 • ACR Convergence 2023

    Paradoxical Antagonistic Association of Visceral and Subcutaneous Adipose Tissue with Circulating C-Reactive Protein in Rheumatoid Arthritis

    Jon Giles and Joan Bathon, Columbia University, New York, NY

    Background/Purpose: C-reactive protein (CRP) is used as an indicator of disease activity in people with RA.However, adipose tissue also expresses inflammatory cytokines that induce hepatic…
  • Abstract Number: 1331 • ACR Convergence 2022

    Risk Factors for Osteoporotic Fracture in Women with Established Long-Term Rheumatoid Arthritis

    Felipe Freire da Silva1, Gisela Machado2, ana Medeiros3, Karina Bonfiglioli4, Andrea Shimabuco2, Liliam Takayama5, Rosa Pereira6 and Diogo Domiciano7, 1FMUSP, Salvador, Brazil, 2FMUSP, São Paulo, Brazil, 3Faculdade de Medicina da Universidade de São Paulo, São Jose Dos Campos, Brazil, 4Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 5University of São Paulo, São Paulo, Brazil, 6Bone Metabolism Laboratory, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 7Hospital das Clinicas, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Low bone mineral density (BMD) is a predictor of osteoporotic fracture. However, individuals with Rheumatoid Arthritis (RA) who sustain "osteoporosis-related" fractures frequently have normal…
  • Abstract Number: 0125 • ACR Convergence 2021

    Body Mass Composition in Post-menopausal Women with Fibromyalgia: Preliminary Results from a Cross-sectional Monocentric Study

    Sabrina Paolino1, Elvis Hysa2, MASCARO ROSSELLA3, Andrea Casabella1, LUCA CARMISCIANO4, Emanuele Gotelli1, Carmen Pizzorni5, Alberto Sulli1, Vanessa Smith6 and Maurizio Cutolo1, 1Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Polyclinic San Martino Hospital, Genoa, Italy, 2Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology Department of Internal Medicine University of Genova Italy IRCCS Polyclinic San Martino, Genoa, Italy, 3Laboratory od Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genoa, Italy - IRCCS Rheumatology Unit San Martino Polyclinic, Genoa, Italy, 4Department of Health Sciences ( DISSAL), Section of Biostatistics, University of Genova, Genova, Italy, 5Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Dept. Internal Medicine, University of Genova, IRCCS Polyclinic San Martino Hospital, Genoa, Italy, 6Department of Rheumatology and Internal Medicine, Ghent University Hospital, Ghent, Belgium

    Background/Purpose: Fibromyalgia (FM) is characterized by chronic musculoskeletal widespread pain, fatigue, sleep disturbances and functional symptoms. The primary endpoint of our study aimed to determine…
  • Abstract Number: 0131 • ACR Convergence 2020

    Analysis of the Total Body Composition in a Cohort of Patients with Elderly Onset Arthritis

    Anahy María Brandy García1, Melania Martinez-Morillo2, Agueda Prior3, Rosa Serrano1, Lourdes Mateo4, Monica Guma5 and Laia Gifre2, 1Hospital Germans Trias i Pujol, Badalona, Spain, 2Hospital Germans Trias i Pujol, Barcelona, Spain, 3Department of Rheumatology, Hospital Germans Trias i Pujol, Badalona, Spain, 4Department of Rheumatology, Germans Trias i Pujol. University Hospital, Badalona, Badalona, 5University of California San Diego, La Jolla, CA

    Background/Purpose: Inflammatory arthritis in the elderly leads to greater comorbidity than that of the young patients, however, there are few data on body composition in…
  • Abstract Number: 0624 • ACR Convergence 2020

    Association of Regional Body Composition and Physical Function Using the Short Physical Performance Battery Among Peruvian Women with HIV

    Diego Cabrera1, Mijahil Pavel Cornejo Ortega2, Yvett Pinedo3, Patricia Garcia4 and Evelyn Hsieh5, 1Yale University, Universidad Peruana Cayetano Heredia, Lima, Peru, 2Hospital Nacional Arzobispo Loayza, Lima, Peru, 3Hospital Nacional Arzobispo Loayza, Lima, 4Universidad Peruana Cayetano Heredia, Lima, Peru, 5Yale University School of Medicine; West Haven VA, New Haven, CT

    Background/Purpose: The musculoskeletal (MSK) system is significantly affected by HIV and its treatment. Changes in body composition can reflect important changes in bone and MSK…
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