ACR Meeting Abstracts

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Abstracts tagged "biopsies"

  • Abstract Number: 2912 • 2015 ACR/ARHP Annual Meeting

    Concomitant Kidney Disease in Patients with Lupus Nephritis

    Paul Hoover1, Jose A. Gomez Puerta2, Alexander Fine1, Helmut Rennke3 and Karen H. Costenbader4, 1Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2Grupo de Inmunología e Inmunogenética, GICIG, Universidad de Antioquia, Medellín, Colombia, Medellín, Colombia, 3Pathology, Brigham and Women's Hospital, Boston, MA, 4Rheumatology, Immunology & Allergy, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: The most common and clinically and histologically best-characterized SLE kidney disease is lupus nephritis (LN).  However, other forms of kidney disease can and do…
  • Abstract Number: 2917 • 2015 ACR/ARHP Annual Meeting

    Combined Proliferative and Membranous Lupus Nephritis: Is the Prognosis Really Poor?

    Ryota Sakai1, Akiko Shibata1, Kentaro Chino1, Jun Kikuchi2, Tsuneo Kondo1, Ayumi Okuyama1, Hirofumi Takei1 and Koichi Amano1, 1Department of Rheumatology and Clinical Immunology, Saitama Medical Center, Saitama Medical University, Saitama, Japan, 2Rheumatology and Clinical Immunology, Saitama Medical Center, Saitama Medical University, Saitama, Japan

    Background/Purpose: Using light microscopy (LM) or immunofluorescence (IF), combined proliferative and membranous lupus nephritis (LN) is defined as an active proliferative class III/IV lesion and…
  • Abstract Number: 175 • 2015 ACR/ARHP Annual Meeting

    Correlating Semiquantitative Ultrasound Scores with Measured Synovial Thickness

    Ralf G. Thiele1, Darren Tabechian1, Laura C Coates2 and Jennifer H. Anolik1, 1University of Rochester Medical Center, Rochester, NY, 2Medicine, University of Rochester, Rochester, NY

    Background/Purpose: In studies of rheumatoid arthritis using ultrasonography (US), findings of synovial thickening are often reported in semiquantitative scores. For synovial biopsies of small joints,…
  • Abstract Number: 185 • 2015 ACR/ARHP Annual Meeting

    Success Rate and Utility of Ultrasound Guided Synovial Biopsies in Clinical Practice

    Aurélie Najm, Benoît Le Goff and Yves Maugars, Rheumatology, Rheumatology, Nantes, France

    Background/Purpose: Histological and bacteriological analysis of synovial tissue (ST) can be useful in the diagnosis of arthritis of undetermined origin. Ultrasound can assist this biopsy…
  • Abstract Number: 646 • 2015 ACR/ARHP Annual Meeting

    Sicca Syndrome in Rheumatoid Arthritis: Is It a Real Sjögren’s?

    George Fragoulis1, James Reilly1, Shauna Kerr1, Iain. B. McInnes1 and Haralampos M. Moutsopoulos2, 1Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom, 2Department of Pathophysiology, Medical School of Athens, Department of Pathophysiology, Athens, Greece

    Background/Purpose: The histopathological hallmark and a major diagnostic criterion of Sjögren’s syndrome (SS) is the presence of periductal lymphocytic infiltrates in the labial minor salivary…
  • Abstract Number: 1960 • 2015 ACR/ARHP Annual Meeting

    a Structured and Extensive Training Program on Vascular Ultrasound, Results in an Excellent Agreement Between Ultrasound and Temporal Artery Biopsy in the Diagnosis of Giant Cell Arteritis

    Stavros Chrysidis1, Ulrich Fredberg2, Uffe Møller Døhn3, Tove Lorenzen4, Lene Terslev5, Knud Larsen6 and Andreas P Diamantopoulos7, 1Department of Rheumatology, Hospital of Southwest Denmark, Esbjerg, Denmark, 2Department of Internal Medicine, Diagnostic Centre Region Hospital Silkeborg Denmark, Silkeborg, Denmark, 3Center for Rheumatology and Spine Diseases, Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, University of Copenhagen, Glostrup, Denmark, 4Diagnostic Centre, Region Hospital Silkeborg, Silkeborg, Denmark, 5Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, 6otolaryngology, Southwest hospital, Esbjerg, Denmark, 7Rheumatology, Haugesund Hospital for Rheumatic Diseases, Haugesund, Norway

    Background/Purpose: There is an increased use of vascular ultrasound (US) for diagnosing giant cell arteritis (GCA).  Consequently, extensive and structured training of ultrasonographers performing vascular…
  • Abstract Number: 1963 • 2015 ACR/ARHP Annual Meeting

    Specialty of Provider Referring for Temporal Artery Biopsy Affects the Likelihood of Giant Cell Arteritis (GCA) Diagnosis

    Lindsay Lally1 and Robert F. Spiera2, 1Rheumatology, Hospital for Special Surgery, New York, NY, 2Rheumatology, HSS, New York, NY

    Background/Purpose: Presenting signs/symptoms of GCA can be nonspecific and patients can initially present to a spectrum of clinical specialties.  While temporal artery biopsy (TAB) is…
  • Abstract Number: 2160 • 2015 ACR/ARHP Annual Meeting

    The Role of Ultrasound Compared to Biopsy of Temporal Arteries in the Diagnosis and Treatment of Giant Cell Arteritis: A Diagnostic Accuracy and Cost-Effectiveness Study

    Raashid Luqmani1, Ellen Lee2, Surjeet Singh3, Michael Gillett2, Wolfgang A. Schmidt4, Mike Bradburn2, Bhaskar Dasgupta5,6, Andreas P Diamantopoulos7, Wulf Forrester-Barker8, William Hamilton9, Shauna Masters10, Brendan McDonald11, Eugene McNally8, Colin T. Pease12, Jennifer Piper8, John Salmon13, Allan Wailoo2, Konrad Wolfe14, Andrew Hutchings15 and TABUL Study group, 1Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 2School of Health and Related Research, University of Sheffield, Sheffield, United Kingdom, 31Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 4Medical Center for Rheumatology and Clinical Immunology Berlin-Buch, Immanuel Krankenhaus Berlin, Berlin, Germany, 5Rheumatology, Southend University Hospital, Essex, United Kingdom, 6Southend University Hospital, Essex, United Kingdom, 7Rheumatology, Hospital of Southern Norway Trust, Kristiansand, Norway, 8Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 9Primary Care, University of Exeter, Exeter, United Kingdom, 10Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, United Kingdom, 11Department of Neuropathology and Ocular Pathology, Oxford University Hospitals NHS Trust, Oxford, United Kingdom, 12Rheumatology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 13Ophthalmology, Oxford University Hospitals NHS Trust, Oxford, United Kingdom, 14Department of Pathology, Southend University Hospital, Essex, United Kingdom, 15Health Services Research Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom

    Background/Purpose: Giant cell arteritis (GCA) is a relatively common form of primary systemic vasculitis which if untreated can lead to permanent sight loss. It is…
  • Abstract Number: 1659 • 2014 ACR/ARHP Annual Meeting

    The Clinical Relevance of a Repeat Biopsy in Lupus Nephritis (LN) Flares

    Milagros Ricse1, Javier Narváez2, Gloria Albert1, Paula Estrada1, Sergi Heredia1, Andrea Zacarias1, Helena Borrell1, Eulalia Armengol1, Xavier Fulladosa3, Joan Torras3, Olga Capdevila4, Francesca Mitjavila4 and Joan Miquel Nolla1, 1Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 2Rheumatology, Hospital Universitario de Bellvitge. Barcelona. Spain, Barcelona, Spain, 3Nephrology, Hospital Universitario de Bellvitge, Barcelona, Spain, 4Internal Medicine, Hospital Universitario de Bellvitge, Barcelona, Spain

    Background/Purpose: Renal biopsy is the gold standard for assessing renal activity and hence guiding treatment. Whether a repeat renal biopsy is helpful during flares of…
  • Abstract Number: 882 • 2014 ACR/ARHP Annual Meeting

    A Signature of microRNAs Overexpressed in Inflamed Temporal Arteries of Patients with Giant Cell Arteritis

    Stefania Croci1, Alessandro Zerbini1, Luigi Boiardi2, Francesco Muratore2, Alessandra Bisagni3, Giulia Pazzola2, Luca Cimino4, Antonio Moramarco4, Davide Nicoli5, Enrico Farnetti6, Bruno Casali6, Alberto Cavazza3, Maria Parmeggiani7 and Carlo Salvarani2, 1Clinical Immunology, Allergology and Advanced Biotechnologies Unit,, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 2Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 3Pathology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 4Ophthalmology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 5Laboratory of Molecular Biology, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 6Laboratory of Molecular Biology,, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 7Clinical Immunology, Allergology and Advanced Biotechnologies Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy

    Background/Purpose: MicroRNAs (miRNAs) are small, non-coding RNAs that suppress gene expression at post-transcriptional level. MiRNAs can regulate innate and adaptive immunity. Moreover, they have been…
  • Abstract Number: 793 • 2014 ACR/ARHP Annual Meeting

    Preliminary Analysis of Histological Findings in Diagnosis of Giant Cell Arteritis Biopsy Positive Patients

    Surjeet Singh1, Andrew Hutchings2, Wulf Forrester-Barker3, Bhaskar Dasgupta4, Andreas P. Diamantopoulos5, Peter Lanyon6, Malgorzata Magliano7, Brendan McDonald8, Konrad Wolfe9 and Raashid Luqmani10, 1Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 2Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom, 3University of Oxford, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom, 4Department of Rheumatology, Southend University Hospital, Essex, United Kingdom, 5Rheumatology, Hospital of Southern Norway Trust, Kristiansand, Norway, 6Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom, 7Department of Rheumatology,, Stoke Mandeville Hospital, Aylesbury, United Kingdom, 8Department of Pathology, John Radcliffe Hospital, Oxford, United Kingdom, 9Department of Pathology, Southend University Hospital, Essex, United Kingdom, 10Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, United Kingdom

    Background/Purpose A positive temporal artery biopsy (TAB) with giant cells, active inflammation and intimal hyperplasia is the gold standard test for diagnosing temporal arteritis. However,…
  • Abstract Number: 792 • 2014 ACR/ARHP Annual Meeting

    Is Temporal Artery Biopsy the Gold Standard for the Diagnosis of Giant Cell Arteritis?

    Marina Scolnik1, Aldo Fabian Ojeda2, Valeria Scaglioni3 and Enrique R. Soriano4, 1Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 2Departamento de Reumatología, Hospital de Clínicas, FCM-UNA, Asuncion, Paraguay, 3Rheumatology Unit, Internal Medical Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 4Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina

    Background/Purpose: The only test that confirms diagnosis of Giant Cell Arteritis (GCA) is a temporal artery biopsy showing vasculitis with mononuclear cell inflammatory infiltrates, often with…
  • Abstract Number: 791 • 2014 ACR/ARHP Annual Meeting

    Comparison of Clinical Manifestations in Different Histological Subsets of Biopsy-Proven Giant Cell Arteritis

    Luigi Boiardi1, Francesco Muratore1, Alberto Cavazza2, Giovanna Restuccia3, Pierluigi Macchioni1, Giuseppe Germanò1, Nicolò Pipitone1, Gianluigi Bajocchi4 and Carlo Salvarani1, 1Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 2Pathology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 3Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 4Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Japan

    Background/Purpose: Temporal artery biopsy (TAB) showing transmural inflammation is considered the gold standard for the diagnosis of giant cell arteritis (GCA). In some cases of…
  • Abstract Number: 790 • 2014 ACR/ARHP Annual Meeting

    Correlations Between Histopathological Findings and Clinical Manifestations in a Large Monocentric Cohort of Patients with Biopsy-Proven Giant Cell Arteritis

    Luigi Boiardi1, Francesco Muratore1, Giovanna Restuccia2, Alberto Cavazza3, Pierluigi Macchioni1, Giuseppe Germanò1, Nicolò Pipitone1 and Carlo Salvarani1, 1Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 2Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 3Pathology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy

    Background/Purpose: Giant cell arteritis (GCA) is a vasculitis that involves large and medium sized arteries in patients older than 50 years. Temporal artery biopsy (TAB)…
  • Abstract Number: 788 • 2014 ACR/ARHP Annual Meeting

    Fast-Track Diagnostic Procedure for Giant Cell Arteritis

    Alojzija Hočevar1, Ziga Rotar2 and Matija Tomsic3, 1Department of Rheumatology, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia, 2Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia, 3Department of Rheumatology, BioRx.si, University Medical Centre Ljubjana, Ljubljana, Slovenia

    Background/Purpose Giant cell arteritis (GCA) represents the most common primary vasculitis among adults aged 50 years or above. Recently, the national annual incidence rate in…
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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying financial and other sponsors about this policy. If you have questions about the abstract embargo policy, please contact the public relations department at [email protected].

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