Abstracts tagged "biomarkers and synovial cells"

Abstract Number: 1982 • 2019 ACR/ARP Annual Meeting
Senescent Synoviocytes in Knee Osteoarthritis Correlate with Disease Biomarkers, Synovitis, and Knee Pain
Christopher Yohn ¹, Robert O'Brien ¹, Stephanie Lussier ¹, Casey Berridge ¹, Rathi Ryan ¹, Ali Guermazi ², Mahru An ¹, Remi-Martin Laberge ¹, Benjamin Hsu¹, Carl Millward ¹, Kate Doherty ¹ and Jamie Dananberg ¹, ¹Unity Biotechnology, Brisbane, CA, ²Boston Medical Center, Boston
Background/Purpose: Background/Purpose: Cellular senescence is a natural state in which a cell permanently halts division through upregulation of a set of intracellular proteins including p16INK4A…
Abstract Number: 144 • 2017 Pediatric Rheumatology Symposium
Linear Discriminant Analysis of Cultured Fibroblast-like Synoviocytes Identifies 6 Candidate Genes Which Predict Extended Course in Juvenile Idiopathic Arthritis
AnneMarie Brescia¹, Megan Simonds², Suzanne M. McCahan³, Timothy Bunnell³, Kathleen E. Sullivan⁴ and Carlos D. Rosé⁵, ¹Pediatric Rheumatology, Nemours A.I. duPont Hospital for Children, Wilmington, DE, ²Nemours, Nemours Biomedical Research, Wilmington, DE, ³Nemours Biomedical Research, Wilmington, DE, ⁴Allergy Immunology, The Children's Hospital of Philadelphia, Philadelphia, PA, ⁵Pediatric Rheumatology, Nemours/Thomas Jefferson University, Wilmington, DE
Background/Purpose: The goal of this project is the identification of informative synovial biomarkers to predict which children with oligoarticular juvenile idiopathic arthritis (JIA) will have…

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