biomarkers and spondylarthritis Archives

Abstract Number: 1663 • ACR/ARHP Annual Meeting 2016
Assessment of Serum Calprotectin and Osteoprotegerin Levels in a Cohort of Spanish Patients with Axial Spondyloarthritis
Fernanda Genre¹, Carlos Fernández-Díaz¹, Javier Rueda-Gotor¹, Raquel López-Mejías¹, Sara Remuzgo-Martínez¹, Begoña Ubilla¹, Veronica Mijares¹, Alfonso Corrales¹, Virginia Portilla¹, Patricia Fuentevilla¹, Luis Rodriguez-Rodriguez², Ricardo Blanco¹, José Luis Hernandez³ and Miguel Angel Gonzalez-Gay^1,4,5, ¹Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, IDIVAL, Santander, Spain, ²Department of Rheumatology, Hospital Clinico San Carlos, Madrid, Spain, ³Bone Metabolism Unit, Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla, IDIVAL, University of Cantabria, RETICEF, Santander, Spain, ⁴School of Medicine, University of Cantabria, Santander, Spain, ⁵Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Background/Purpose: Calprotectin is a protein involved in several cellular processes including immunomodulation1. Elevated levels of this protein have been observed in inflammatory diseases, since it…
Abstract Number: 2718 • ACR/ARHP Annual Meeting 2016
Plasma Levels of the M2 Macrophage Markers, CD163 and CD206, Changes Reversely and Soluble CD163 Is Associated with Disease Activity in Spondyloarthritis
Line Dam Heftdal^1,2, René Østgård^3,4, Malene Hvid^3,5, Bent Deleuran^2,3,5, Holger Jon Møller⁵ and Stinne Greisen^2,3, ¹Department of Biomedicine, Department of Biomedicine, Aarhus University, Aarhus, Denmark, ²Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ³Department of Biomedicine, Aarhus University, Aarhus, Denmark, ⁴Department of Rheumatology, Regional Hospital Silkeborg, Silkeborg, Denmark, ⁵Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Background/Purpose: Spondyloarthritis (SpA) covers a group of interrelated auto-inflammatory disorders where TNFa is a central mediator of disease. T cells and macrophages are abundant in…
Abstract Number: 576 • ACR/ARHP Annual Meeting 2014
Dikkopf-1 (Dkk-1) Serum Levels in Axial Spondyloarthritis (axSpA) Are Related to Disease Duration
Victoria Navarro-Compán¹, Enrique Melguizo-Madrid², Concepción González-Rodríguez³, Federico Navarro-Sarabia⁴ and Rafael Ariza-Ariza⁴, ¹Rheumatology, University Hospital La Paz and Leiden University Medical Center, Madrid, Spain, ²Biochemistry, University Hospital Virgen Macarena, Sevilla, Spain, ³University Hospital Virgen Macarena, Sevilla, Spain, ⁴Rheumatology, University Hospital Virgen Macarena, Sevilla, Spain

Background/Purpose: Tumor necrosis factor (TNF) alpha is responsible for induction of dkk-1 which down-regulates bone formation. Therefore, it was expected that TNF-blocker therapy would inhibit…
Abstract Number: 555 • ACR/ARHP Annual Meeting 2014
Urinary Excretion of Type II Collagen C-Telopeptide and Glucosyl-Galactosyl-Pyridinoline As Prognostic Biomarkers in Early Spondyloarthritis
Elisa Trujillo¹ and Maria del Mar Trujillo², ¹Servicio de Reumatologia, Hospital Universitario de Canarias, La Laguna, Tenerife, Spain, ²Servicio de evaluacion y planificacion, Servicio Canario de la Salud, Tenerife, Spain
Background/Purpose: The search for biomarkers in spondyloarthritis (SpA) is of great interest because of their diagnostic and prognostic role in the treatment of these diseases.…
Abstract Number: 936 • ACR/ARHP Annual Meeting 2013
Decreased Plasma Levels Of Soluble CD18 Link Leukocyte Migration and Disease Activity In Spondyloarthritis
Tue W. Kragstrup^1,2, Babak Jalilian¹, Malene Hvid³, René Østgård⁴, Berit Schiøttz-Christensen⁵, Anne G. Jurik⁶, William H. Robinson², Thomas Vorup-Jensen¹ and Bent Deleuran^1,7, ¹Department of Biomedicine, Aarhus University, Aarhus, Denmark, ²Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, ³Dept. of Clinical Medicine, Aarhus University, Aarhus, Denmark, ⁴Dept. of Biomedicine, Aarhus University, Aarhus, Denmark, ⁵Aarhus Rheumatology Clinic, Private practice, Aarhus, Denmark, ⁶Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, ⁷Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark
Background/Purpose: Spondyloarthritis (SpA) comprise a group of diseases characterized by inflammation of the entheses and joints of the axial skeleton primarily driven by innate immune…

Abstracts tagged "biomarkers and spondylarthritis"

Assessment of Serum Calprotectin and Osteoprotegerin Levels in a Cohort of Spanish Patients with Axial Spondyloarthritis

Plasma Levels of the M2 Macrophage Markers, CD163 and CD206, Changes Reversely and Soluble CD163 Is Associated with Disease Activity in Spondyloarthritis

Dikkopf-1 (Dkk-1) Serum Levels in Axial Spondyloarthritis (axSpA) Are Related to Disease Duration

Urinary Excretion of Type II Collagen C-Telopeptide and Glucosyl-Galactosyl-Pyridinoline As Prognostic Biomarkers in Early Spondyloarthritis

Decreased Plasma Levels Of Soluble CD18 Link Leukocyte Migration and Disease Activity In Spondyloarthritis