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Abstracts tagged "Biomarkers and psoriatic arthritis"

  • Abstract Number: 651 • 2017 ACR/ARHP Annual Meeting

    Role of Mir-21-5p As a Potential Biomarker of Psoriatic Arthritis and Response to Treatment

    Rohan Machhar1, Justine (Yang) Ye1, Vinod Chandran2 and Dafna D Gladman3, 1University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Psoriatic arthritis (PsA) is an inflammatory arthritis occurring in patients with psoriasis. miRNA’s are small non coding RNAs whose main function, at a post…
  • Abstract Number: 1738 • 2015 ACR/ARHP Annual Meeting

    Assessing the Validity of the Multi-Biomarker Disease Activity Assay in Patients with Psoriatic Arthritis

    Tristan Boyd1, Doquyen H. Huynh1, P. Scott Eastman2, Ferhan Qureshi3, Eric H. Sasso4, Rebecca J. Bolce4, Joshua Hillman5, David L. Boyle6 and Arthur Kavanaugh7, 1Rheumatology, University of California San Diego, La Jolla, CA, 2Crescendo Bioscience, South San Francisco, CA, 3Crescendo Bioscience, Inc., South San Francisco, CA, 4Crescendo Bioscience Inc., South San Francisco, CA, 5Div of Rheum, UCSD School of Medicine, La Jolla, CA, 6Division of Rheumatology, Allergy and Immunology, University of California, San Diego, La Jolla, CA, 7University of California, San Diego School of Medicine, LaJolla, CA

    Background/Purpose: Considerable heterogeneity across clinical domains of psoriatic arthritis (PsA) can make assessment of disease activity challenging. As a result, there has been interest in…
  • Abstract Number: 1593 • 2014 ACR/ARHP Annual Meeting

    Neutrophil-Lymphocyte Ratio As a Marker of Disease Activity in Psoriatic Arthritis

    Vinod Chandran1, Arane Thavaneswaran2 and Dafna D. Gladman1, 1University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. There are few biomarkers for disease activity in PsA. Traditional acute phase reactants are…
  • Abstract Number: 2501 • 2013 ACR/ARHP Annual Meeting

    Validation Of Gene Expression Biomarkers Of Psoriatic Arthritis

    Fatima Abji1, Remy Pollock1, Fawnda Pellett2, Kun Liang3, Vinod Chandran2 and Dafna D. Gladman2, 1University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada

    Background/Purpose: Psoriatic arthritis (PsA) is a seronegative immune mediated arthritis that develops in about a third of patients with cutaneous psoriasis (PsC). The cellular pathways…
  • Abstract Number: 534 • 2013 ACR/ARHP Annual Meeting

    Peripheral Blood Gene Expression Profiling Of Psoriatic Arthritis Patient

    Bidisha Dasgupta, Yauheniya Cherkas, Sarah Lamberth and Carrie Brodmerkel, Janssen Research & Development, LLC., Spring House, PA

    Background/Purpose: Although PsA is heterogeneous and shows signs of rheumatoid arthritis (RA) and psoriasis (PsO), genetic studies indicate that PsA is a distinct disease with…
  • Abstract Number: 1350 • 2012 ACR/ARHP Annual Meeting

    Inflammatory Biomarkers in Psoriatic Arthritis

    Ibrahim AlHomood1, Arane Thavaneswaran1, D. D. Gladman2 and Vinod Chandran3, 1Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, 2Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, 3Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose:  Psoriatic arthritis (PsA) is an inflammatory arthritis that may progress rapidly and result in joint damage and disability. The aim of this study was…
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