biomarkers and proteomics Archives - ACR Meeting Abstracts

Abstract Number: 1868 • ACR/ARP Annual Meeting 2019
Clinical Correlations of Autoantibodies Against Heat Shock Cognate 71 kDa Protein in Patients with Juvenile Dermatomyositis
Rie Karasawa¹, James N. Jarvis ², Toshiko Sato ¹, Megumi Tanaka ¹, Mark Hicar ², Kazuo Yudoh ¹, Terrance O’Hanlon ³, Payam Noroozi-Farhadi ³ and Lisa G. Rider ⁴, ¹Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan, ²University at Buffalo, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, ³NIEHS, NIH, Bethesda, MD, ⁴Environmental Autoimmunity Group, Clinical Research Branch, NIEHS, NIH, Bethesda, MD
Background/Purpose: Juvenile dermatomyositis (JDM) is an inflammatory myopathy characterized by prominent vascular and perivascular inflammation in affected skeletal muscles. The mechanisms of vessel injury in…
Abstract Number: 765 • ACR/ARHP Annual Meeting 2017
Proteomic Analysis of Scleroderma Associated Joint Disease
Chan Kim¹, Julio Mantero², Robert A. Lafyatis³ and Robert W. Simms⁴, ¹Rheumatology and Clinical Epidemiology, Boston University School of Medicine, Boston, MA, ²Arthritis Center, Boston University School of Medicine, Boston, MA, ³Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, ⁴Rheumatology, Boston University School of Medicine, Boston, MA
Background/Purpose: The pathophysiology of joint disease in scleroderma, a heterogeneous multisystem disease mostly characterized by fibrosis, is unknown. We performed proteomic analysis of serum in…
Abstract Number: 1253 • ACR/ARHP Annual Meeting 2015
Identification and Validation of Novel Putative Salivary Proteomic Biomarkers in Sjögren’s Syndrome and Different Disease Subsets
Chiara Baldini¹, Daniela Martini¹, Nadia Ucciferri², Silvia Rocchiccioli², Letizia Mattii³, Antonietta Raffaella Maria Sabbatini³, Francesca Sernissi¹, Francesco Ferro¹, Nicoletta Luciano¹, Leonardo Lorenzini¹, Marta Mosca⁴, Stefano Bombardieri¹ and Antonella Cecchettini³, ¹Rheumatology Unit, University of Pisa, Italy, Pisa, Italy, ²Institute of Clinical Physiology, Pisa, Italy, Pisa, Italy, ³Department of Clinical and Experimental Medicine, University of Pisa, Italy, Pisa, Italy, ⁴University of Pisa, Pisa, Italy
Background/Purpose: Salivary proteomics has recently appeared as a promising tool for the identification of novel diagnostic biomarkers for primary Sjögren’s syndrome (SS). However, to date…
Abstract Number: 2977 • ACR/ARHP Annual Meeting 2014
Distinct Serum Protein Signature and Novel Biomarkers of primary Sjogren’s Syndrome Revealed by comprehensive High-Throughput Proteomic Analysis
Ayumi Nishikawa¹, Katsuya Suzuki², Yoshiaki Kassai³, Yuumi Gotou⁴, Takahiro Miyazaki³, Maiko Takiguchi⁵, Masaru Takeshita¹, Atsuko Murota², Rimpei Morita⁶, Akihiko Yoshimura⁶ and Tsutomu Takeuchi², ¹Division of Rheumatology and Clinical Immunology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ²Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ³Inflammation Drug Discovery Unit, Takeda Pharmaceutical Company Limited, Kanagawa, Japan, ⁴Inflammation Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Tokyo, Tokyo, Japan, ⁵Inflammation Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Tokyo, Japan, ⁶Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
Background/Purpose: The EULAR SS Disease Activity Index (ESSDAI) is currently used as an objective evaluation method of clinical disease activity in clinical research into primary…
Abstract Number: 2645 • ACR/ARHP Annual Meeting 2013
Pathological Roles Of The Anti-Oxidative Enzyme Peroxiredoxin 2 In Patients With Kawasaki Disease
Rie Karasawa¹, Toshiko Sato¹, Mayumi Tamaki¹, Mikiya Fujieda², Kazuhide Ohta³ and Kazuo Yudoh¹, ¹Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan, ²Department of Pediatrics, Kochi Medical School, Nankoku, Japan, ³Department of Pediatrics, Kanazawa Medical Center, Kanazawa, Japan
Background/Purpose: Anti-endothelial cell antibodies (AECA) are autoantibodies that are detected frequently in vasculitis caused by, for example, Kawasaki disease (KD). However, AECA target molecules have…
Abstract Number: 1905 • ACR/ARHP Annual Meeting 2013
Protein Profiles Of Peripheral Blood Mononuclear Cells As a Biomarker For Behcet’s Disease
Manae Kurokawa¹, Takuya Yoshioka², Toshiyuki Sato¹, Kouhei Nagai¹, Nobuko Iizuka¹, Mitsumi Arito¹, Yukiko Takakuwa², Hiromasa Nakano², Seido Ooka², Naoya Suematsu¹, Kazuki Okamoto¹, HIroshi Nakamura³, Noboru Suzuki⁴, Shoichi Ozaki⁵ and Tomohiro Kato¹, ¹Clinical Proteomics and Molecular Medicine, St. Marianna University Graduate School of Medicine, Kawasaki, Japan, ²Division of Rheumatology and Allergy, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan, ³Department of Rheumatology, Nippon Medical School, Bunkyo-ku, Japan, ⁴Department of Immunology and Medicine, St. Marianna University School of Medicine, Kawasaki, Japan, ⁵Division of Rheumatology and Allergy, Department of Internal Medicine, St. Marianna University School of Medicine, St. Marianna University School of Medicine, Kawasaki, Japan
Background/Purpose: To investigate the pathophysiology of Behcet’s disease (BD) and find biomarker candidates for the disease, we analyzed protein profiles of peripheral blood mononuclear cells…

Abstracts tagged "biomarkers and proteomics"

Clinical Correlations of Autoantibodies Against Heat Shock Cognate 71 kDa Protein in Patients with Juvenile Dermatomyositis

Proteomic Analysis of Scleroderma Associated Joint Disease

Identification and Validation of Novel Putative Salivary Proteomic Biomarkers in Sjögren’s Syndrome and Different Disease Subsets

Distinct Serum Protein Signature and Novel Biomarkers of primary Sjogren’s Syndrome Revealed by comprehensive High-Throughput Proteomic Analysis

Pathological Roles Of The Anti-Oxidative Enzyme Peroxiredoxin 2 In Patients With Kawasaki Disease

Protein Profiles Of Peripheral Blood Mononuclear Cells As a Biomarker For Behcet’s Disease