ACR Meeting Abstracts

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Abstracts tagged "biomarkers and proteomics"

  • Abstract Number: 1868 • 2019 ACR/ARP Annual Meeting

    Clinical Correlations of Autoantibodies Against Heat Shock Cognate 71 kDa Protein in Patients with Juvenile Dermatomyositis

    Rie Karasawa1, James N. Jarvis 2, Toshiko Sato 1, Megumi Tanaka 1, Mark Hicar 2, Kazuo Yudoh 1, Terrance O’Hanlon 3, Payam Noroozi-Farhadi 3 and Lisa G. Rider 4, 1Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan, 2University at Buffalo, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, 3NIEHS, NIH, Bethesda, MD, 4Environmental Autoimmunity Group, Clinical Research Branch, NIEHS, NIH, Bethesda, MD

    Background/Purpose: Juvenile dermatomyositis (JDM) is an inflammatory myopathy characterized by prominent vascular and perivascular inflammation in affected skeletal muscles. The mechanisms of vessel injury in…
  • Abstract Number: 765 • 2017 ACR/ARHP Annual Meeting

    Proteomic Analysis of Scleroderma Associated Joint Disease

    Chan Kim1, Julio Mantero2, Robert A. Lafyatis3 and Robert W. Simms4, 1Rheumatology and Clinical Epidemiology, Boston University School of Medicine, Boston, MA, 2Arthritis Center, Boston University School of Medicine, Boston, MA, 3Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 4Rheumatology, Boston University School of Medicine, Boston, MA

    Background/Purpose: The pathophysiology of joint disease in scleroderma, a heterogeneous multisystem disease mostly characterized by fibrosis, is unknown.  We performed proteomic analysis of serum in…
  • Abstract Number: 1253 • 2015 ACR/ARHP Annual Meeting

    Identification and Validation of Novel Putative Salivary Proteomic Biomarkers in Sjögren’s Syndrome and Different Disease Subsets

    Chiara Baldini1, Daniela Martini1, Nadia Ucciferri2, Silvia Rocchiccioli2, Letizia Mattii3, Antonietta Raffaella Maria Sabbatini3, Francesca Sernissi1, Francesco Ferro1, Nicoletta Luciano1, Leonardo Lorenzini1, Marta Mosca4, Stefano Bombardieri1 and Antonella Cecchettini3, 1Rheumatology Unit, University of Pisa, Italy, Pisa, Italy, 2Institute of Clinical Physiology, Pisa, Italy, Pisa, Italy, 3Department of Clinical and Experimental Medicine, University of Pisa, Italy, Pisa, Italy, 4University of Pisa, Pisa, Italy

    Background/Purpose: Salivary proteomics has recently appeared as a promising tool for the identification of novel diagnostic biomarkers for primary Sjögren’s syndrome (SS). However, to date…
  • Abstract Number: 2977 • 2014 ACR/ARHP Annual Meeting

    Distinct Serum Protein Signature and Novel Biomarkers of primary Sjogren’s Syndrome Revealed by comprehensive High-Throughput Proteomic Analysis

    Ayumi Nishikawa1, Katsuya Suzuki2, Yoshiaki Kassai3, Yuumi Gotou4, Takahiro Miyazaki3, Maiko Takiguchi5, Masaru Takeshita1, Atsuko Murota2, Rimpei Morita6, Akihiko Yoshimura6 and Tsutomu Takeuchi2, 1Division of Rheumatology and Clinical Immunology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 2Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 3Inflammation Drug Discovery Unit, Takeda Pharmaceutical Company Limited, Kanagawa, Japan, 4Inflammation Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Tokyo, Tokyo, Japan, 5Inflammation Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Tokyo, Japan, 6Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan

    Background/Purpose: The EULAR SS Disease Activity Index (ESSDAI) is currently used as an objective evaluation method of clinical disease activity in clinical research into primary…
  • Abstract Number: 2645 • 2013 ACR/ARHP Annual Meeting

    Pathological Roles Of The Anti-Oxidative Enzyme Peroxiredoxin 2 In Patients With Kawasaki Disease

    Rie Karasawa1, Toshiko Sato1, Mayumi Tamaki1, Mikiya Fujieda2, Kazuhide Ohta3 and Kazuo Yudoh1, 1Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan, 2Department of Pediatrics, Kochi Medical School, Nankoku, Japan, 3Department of Pediatrics, Kanazawa Medical Center, Kanazawa, Japan

    Background/Purpose: Anti-endothelial cell antibodies (AECA) are autoantibodies that are detected frequently in vasculitis caused by, for example, Kawasaki disease (KD). However, AECA target molecules have…
  • Abstract Number: 1905 • 2013 ACR/ARHP Annual Meeting

    Protein Profiles Of Peripheral Blood Mononuclear Cells As a Biomarker For Behcet’s Disease

    Manae Kurokawa1, Takuya Yoshioka2, Toshiyuki Sato1, Kouhei Nagai1, Nobuko Iizuka1, Mitsumi Arito1, Yukiko Takakuwa2, Hiromasa Nakano2, Seido Ooka2, Naoya Suematsu1, Kazuki Okamoto1, HIroshi Nakamura3, Noboru Suzuki4, Shoichi Ozaki5 and Tomohiro Kato1, 1Clinical Proteomics and Molecular Medicine, St. Marianna University Graduate School of Medicine, Kawasaki, Japan, 2Division of Rheumatology and Allergy, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan, 3Department of Rheumatology, Nippon Medical School, Bunkyo-ku, Japan, 4Department of Immunology and Medicine, St. Marianna University School of Medicine, Kawasaki, Japan, 5Division of Rheumatology and Allergy, Department of Internal Medicine, St. Marianna University School of Medicine, St. Marianna University School of Medicine, Kawasaki, Japan

    Background/Purpose: To investigate the pathophysiology of Behcet’s disease (BD) and find biomarker candidates for the disease, we analyzed protein profiles of peripheral blood mononuclear cells…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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