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Abstracts tagged "biomarkers and monoclonal antibodies"

  • Abstract Number: 875 • 2017 ACR/ARHP Annual Meeting

    Serum Autoantibody Profiling of Primary Sjoegren’s Syndrome Patients Reveals Novel Biomarkers Associated with the Disease, Disease Activity, and Clinical Response to VAY736

    Petra Budde1, Julie Doucet2, Hans-Dieter Zucht1, Remi Kazma2, Paul Maguire2, Alexandre Avrameas2, Marie-Anne Valentin2, Stephen Oliver2, Peter Schulz-Knappe1 and Alessandra Vitaliti2, 1Protagen AG, Dortmund, Germany, 2Translational Medicine, Novartis Institutes for Biomedical Research, Basel, Switzerland

    Background/Purpose: Overexpression of B cell activating factor (BAFF) in salivary glands contributes to the pathogenesis of primary Sjögren’s syndrome (pSS) by promoting autoantibody (AAB) production.…
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ACR Pediatric Rheumatology Symposium 2020

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