ACR Meeting Abstracts

ACR Meeting Abstracts

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Abstracts tagged "biomarkers and flow cytometry"

  • Abstract Number: 1917 • 2017 ACR/ARHP Annual Meeting

    A Novel Type I Interferon Biomarker on B Cell Predicts with Disease Activity in SLE and Can be Measured By Cell Surface Tetherin (CD317)

    Yasser M El-Sherbiny1,2,3, Md Yuzaiful Md Yusof1, Antonios Psarras1, Elizabeth M.A. Hensor1, Kumba Kabba1, Alaa Mohamed1,4, Miriam Wittmann5, Paul Emery5,6 and Edward M Vital1,5,7, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 2NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals, NHS Trust, Leeds, United Kingdom, 3Clinical Pathology dept., School of Medicine, Mansoura University, Mansoura, Egypt, 4Faculty of Medicine, Assiut University, Department of Rheumatology and Rehabilitation, Assiut, Egypt, 5NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 6University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom, 7University of Leeds, Leeds, United Kingdom

    Background/Purpose: SLE is an IFN-I-mediated disease with dysregulated handling of self-nuclear antigens triggering anti-viral immune mechanisms. The level of IFN-I activity appears to stratify for…
  • Abstract Number: 3157 • 2015 ACR/ARHP Annual Meeting

    B Cell Profile As a Biomarker of Disease Segmentation and Flare Prognosis in SLE

    Chungwen Wei1, Bridget Neary2, Jamie Biear3, Jennifer Barnard3,4, Michelle Petri5, Alex Rosenberg6, Jennifer H. Anolik7 and Ignacio Sanz1, 1Rheumatology, Emory University, Atlanta, GA, 2Emory University, Atlanta, GA, 3Rheumatology, University of Rochester, Rochester, NY, 4Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, 5Rheumatology, Johns Hopkins University Hospital, Baltimore, MD, 6University of Rochester, Rochester, NY, 7University of Rochester Medical Center, Rochester, NY

    Background/Purpose: B cell abnormalities in SLE are well-established contributors to disease pathogenesis. Perturbation of B cell homeostasis in SLE is often described separately for each…
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ACR Pediatric Rheumatology Symposium 2020

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