Abstracts tagged "Biomarkers and epigenetics"

Abstract Number: 2804 • 2015 ACR/ARHP Annual Meeting
The Global miRNA Whole Blood Profile of Ankylosing Spondylitis
Carolina Mejia Otero¹, Shervin Assassi¹, Michael H. Weisman², Michael M. Ward³, Lianne S. Gensler⁴, Matthew A. Brown⁵, Minghua Wu¹, John Hagan⁶, John D. Reveille⁷ and Gloria Salazar¹, ¹Rheumatology, University of Texas Medical School at Houston, Houston, TX, ²Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ³NIH/NIAMS, Bethesda, MD, ⁴Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ⁵The University of Queensland Diamantina Institute, Brisbane, Australia, ⁶Neurosurgery, University of Texas at Houston, Houston, TX, ⁷Internal Medicine/Rheumatology, University of Texas Medical School at Houston, Houston, TX
Background/Purpose: MicroRNA (miRNA) are small non-coding RNAs that play an important role in posttranscriptional gene regulation and their involvement in the pathophysiology of several autoimmune…
Abstract Number: 2594 • 2012 ACR/ARHP Annual Meeting
Epigenetic Signature of the Response to Anti-TNF in Juvenile Idiopathic Arthritis
Roberto Spreafico¹, Maura Rossetti¹, Hong Zhang¹, Maryam Moshref¹, Carol Wallace², D. J. Lovell³ and Salvatore Albani⁴, ¹Translational Immunology, Sanford-Burnham Medical Research Institute, La Jolla, CA, ²Div Rheumatology-Pediatrics, Childrens Hosp & Regional Med, Seattle, WA, ³Cincinnati Children's Hospital, Cincinnati, OH, ⁴Translational Research Program, Infectious and Inflammatory Diseases, Sanford-Burnham Medical Research Institute, La Jolla, CA
Background/Purpose: The identification of prognostic markers of responsiveness to the therapy in JIA would not only radically improve clinical management, but also shed light on…