ACR Meeting Abstracts

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Abstracts tagged "biomarkers and complement"

  • Abstract Number: 1762 • 2018 ACR/ARHP Annual Meeting

    Plasma iC3b Level As a Biomarker of Disease Relapse in ANCA-Associated Vasculitis

    Catherine E. Najem1, Martin Schmidt2, Chad Stiening3, David Cuthbertson4, Simon Carette5, Nader A. Khalidi6, Curry L. Koening7, Carol Langford8, Carol A. McAlear9, Paul A. Monach10, Larry W. Moreland11, Christian Pagnoux12, Philip Seo13, Ulrich Specks14, Antoine G. Sreih1, Steven R. Ytterberg15 and Peter A. Merkel16,17, 1Rheumatology, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 2Kypha, Inc., St. Louis, MO, 3Kypha, Inc., St Louis, MO, 4Biostatistics and Informatics, Department of Pediatrics, Department of Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL, 5Division of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, 6Rheumatology, McMaster University, Hamilton, ON, Canada, 7Rheumatology, Division of Rheumatology, University of Utah, Salt Lake City, UT, 8Rheumatic and Immunologic Diseases, Department of Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, 9Division of Rheumatology, University of Pennsylvania; Perelman School of Medicine, Philadelphia, PA, 10Section of Rheumatology, Boston University School of Medicine, Boston, MA, 11Division of Rheumatology and Clinical Immunology, Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, 12Division of Rheumatology, Division of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, 13Medicine, Division of Rheumatology, Johns Hopkins University, Baltimore, MD, 14Mayo Clinic College of Medicine, Rochester, MN, 15Rheumatology, Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN, 16Division of Rheumatology, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 17Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA

    Background/Purpose:C3, the central protein of the complement cascade, participates in an amplification loop that can lead to complement deposition and host tissue damage. If elevated,…
  • Abstract Number: 2800 • 2016 ACR/ARHP Annual Meeting

    Cell-Bound Complement Activation Products in Multi-Analyte Assay with Algorithm Aid the Diagnosis of Systemic Lupus Erythematosus

    James Mossell1, John A. Goldman2, Derren Barken3 and Roberta Alexander4, 1Tift Regional Medical Center, Tifton, GA, 2Medical Quarters #293, Emory St. Joseph’s Hospital, Atlanta, GA, 3Exagen Diagnostics, Vista, CA, 4Research & Development, Exagen Diagnostics, Vista, CA

    Background/Purpose: Cell-bound complement activation products (CB-CAPs) are sensitive and specific biomarkers in the differential diagnosis of systemic lupus erythematosus (SLE) and other rheumatic diseases, as…
  • Abstract Number: 817 • 2015 ACR/ARHP Annual Meeting

    Circulating Endothelial Cell (CEC) and CEC-Bound C4d Levels As Biomarkers of Systemic Lupus Erythematosus

    Chau-Ching Liu1, Susan Manzi2 and Joseph Ahearn3, 1Allegheny Singer Research Institute, Pittsburgh, PA, 2Rheumatology, Allegheny Health Network, Pittsburgh, PA, 3Allegheny Singer Research Institute, Allegheny Health Network, Pittsburgh, PA

    Background/Purpose: Accelerated atherosclerotic disease has been widely recognized in patients with SLE. Circulating endothelial cells (CECs) are a rare cell population believed to detach from…
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ACR Pediatric Rheumatology Symposium 2020

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