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Abstracts tagged "biomarkers and cartilage"

  • Abstract Number: 1373 • ACR/ARHP Annual Meeting 2018

    Predictive Probabilities Are Superior in Communicating the Clinical Relevance of Cartilage Thickness As an Imaging Biomarker of Knee Osteoarthritis Progression

    C. Kent Kwoh1,2, Erin L. Ashbeck1, Edward J. Bedrick3 and Felix Eckstein4,5, 1University of Arizona Arthritis Center, Tucson, AZ, 2Division of Rheumatology, Department of Medicine, The University of Arizona, Tucson, AZ, 3Department of Epidemiology and Biostatistics, University of Arizona, Tucson, AZ, 4Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria, 5Chondrometrics GmbH, Ainring, Germany

    Background/Purpose: Establishing a threshold of clinically important cartilage loss is of great interest for the design and interpretation of knee OA trials of structure-modifying treatments.…
  • Abstract Number: 162 • ACR/ARHP Annual Meeting 2016

    Automated Segmentation of Cartilage Provides Comparable Accuracy and Better Responsiveness Than Manual Segmentation: Data from the Osteoarthritis Initiative

    Gwenael Guillard1, Graham R. Vincent1, Philip G. Conaghan2, Alan Brett3 and Michael A Bowes1, 1Imorphics Ltd, Manchester, United Kingdom, 2NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, 3Imorphics Ltd, MANCHESTER, United Kingdom

    Automated Segmentation of Cartilage Provides Comparable Accuracy and Better Responsiveness Than Manual Segmentation: Data from the Osteoarthritis Initiative *Guillard G., *Vincent G.R., *Brett, A., **Conaghan,…
  • Abstract Number: 2537 • ACR/ARHP Annual Meeting 2012

    Cross-Sectional and Longitudinal Associations Between Circulating Leptin and Knee Cartilage Thickness in Older Adults

    Oliver Stannus1, Yuelong Cao2, Benny Samuel Eathakkattu Antony1, Graeme Jones3 and Changhai Ding4, 1Musculoskeletal, Menzies Research Institute Tasmania, Hobart, Australia, 2Musculoskeletal, Orthopaedics, Menzies Research Institute Tasmania, Research Institute of Orthopaedics, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,, Hobart, Australia, 3Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, 4Musculoskeletal and Epidemilogy, Menzies research institute & Monash University, Hobart, Australia

    Background/Purpose: To investigate cross-sectional and longitudinal associations between serum leptin levels and knee cartilage thickness in older adults. Methods: A prospective cohort of 163 randomly…

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