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Abstracts tagged "biomarkers and canakinumab"

  • Abstract Number: 2917 • 2018 ACR/ARHP Annual Meeting

    Multiplex Serum Biomarker Analysis before and during Therapy with Canakinumab in Patients with Systemic Juvenile Idiopathic Arthritis

    Tanja Hinze1, Christoph Kessel1, Claas Hinze1, Julia Seibert2, Hermann Gram2 and Dirk Foell3, 1Department of Pediatric Rheumatology and Immunology, University of Muenster, Muenster, Germany, 2Novartis, Basel, Switzerland, 3Pediatric Rheumatology and Immunology, University of Muenster, Muenster, Germany

    Background/Purpose: Canakinumab (CAN), a monoclonal anti-interleukin (IL)-1β antibody, is approved for the treatment of systemic juvenile idiopathic arthritis (SJIA). CAN-treated patients with SJIA showed a…
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