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Abstracts tagged "Biologics and ankylosing spondylitis (AS)"

  • Abstract Number: 1258 • 2019 ACR/ARP Annual Meeting

    Effects of Intravenous Golimumab, an Anti-TNFα Monoclonal Antibody, on Health-Related Quality of Life in Patients with Ankylosing Spondylitis: 1-Year Results of a Phase III Trial

    John Reveille1, Atul Deodhar 2, Diane Harrison 3, Elizabeth Hsia 4, Eric K H Chan 3, Shelly Kafka 5, Kim Hung Lo 3, Lilianne Kim 3 and Chenglong Han 3, 1University of Texas McGovern Medical School, Houston, 2Oregon Health & Science University, Portland, OR, 3Janssen Research & Development, LLC, Spring House, PA, 4Janssen Research & Development, LLC/University of Pennsylvania, Spring House/Philadelphia, PA, 5Janssen Scientific Affairs, LLC, Horsham, PA

    Background/Purpose: In patients with ankylosing spondylitis (AS), IV administration of the anti-TNFa antibody golimumab (GLM-IV) resulted in improvements in composite measures of various aspects of…
  • Abstract Number: 2498 • 2017 ACR/ARHP Annual Meeting

    Rheumatologists Use Different Cut-Offs for Disease Activity in Real Life – the Experience with Golimumab in Ankylosing Spondylitis- Subanalysis from a Non-Interventional German Study

    Jürgen Braun1, Xenofon Baraliakos2, Uta Kiltz1, Klaus Krüger3, Gerd R. Burmester4, Siegfried Wassenberg5 and Matthias H. Thomas6, 1Rheumazentrum Ruhrgebiet, Herne, Germany, 2Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 3Praxiszentrum St. Bonifatius München, München, Germany, 4Department of Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Free University and Humboldt University Berlin, Berlin, Germany, 5Rheumazentrum Ratingen, Ratingen, Germany, 6Medical Affairs, MSD Sharp & Dohme GmbH, Bünde, Germany

    Background/Purpose: International recommendations for the management of axial spondyloarthritis including ankylosing spondylitis (AS) suggest a BASDAI level of disease activity of ≥4 to indicate treatment…
  • Abstract Number: 2861 • 2015 ACR/ARHP Annual Meeting

    Treatment Patterns of Subcutaneous Biologic Agent Use Among Patients with Ankylosing Spondylitis

    Sergio Schwartzman1, Yunfeng Li2, Huanxue Zhou3, Vivian Herrera2 and Jacqueline B. Palmer2, 1Hospital for Special Surgery, New York, NY, 2Novartis Pharmaceuticals Corporation, East Hanover, NJ, 3KMK Consulting Inc, East Hanover, NJ

    Background/Purpose: Ankylosing spondylitis (AS) is characterized by chronic debilitating inflammation of the spine and/or sacroiliac joints. Several biologic agents have been approved for the treatment…
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