Abstracts tagged "biologic response modifiers and rituximab"

Abstract Number: 1755 • 2012 ACR/ARHP Annual Meeting
The Alternative ΔCD20 Transcript Variant Is Not Expressed in B Cells and Synovial Tissue From Patients with Rheumatoid Arthritis
Clémentine Gamonet¹, Marina Deschamps², Béatrice Gaugler³, Philippe Saas⁴, Isabelle Auger⁵, Christophe Ferrand⁴, Eric Toussirot⁶ and CIC BT506⁷, ¹INSERM UMR1098/ Etablissement Français du Sang / Université de Franche Comté, France, ²INSERM UMR1098 / Etablissement Français du Sang/ Université de Franche Comté, Besançon, France, ³EFS Bourgogne Franche Comté, INSERM UMR1098 / Etablissement Français du Sang / Université de Franche Comté, Besançon, France, ⁴Etablisement Français du Sang ; Université de Franche Comté, INSERM UMR1098, Besançon, France, ⁵Université Aix Marseille II, INSERM UMR1097, Marseille, France, ⁶University Hospital, CIC Biotherapy 506 and Rheumatology and EA 4266 Pathogens and Inflammation, Besançon, France, ⁷Chru, Clinical Investigation Center Biotherapy 506, Besançon, France
Background/Purpose: determining predictive factors for response to biologics may help to select appropriate treatment in patients with RA. Rituximab (RTX) is a chimeric monoclonal antibody…