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Abstracts tagged "biologic drugs and clinical trials"

  • Abstract Number: 1884 • ACR/ARHP Annual Meeting 2017

    Mepolizumab for the Treatment of Patients with Eosinophilic Granulomatosis with Polyangiitis: Post-Hoc Results of a Phase III Randomized, Placebo-Controlled Trial

    Jonathan Steinfeld1, Eric S Bradford2, Judith Brown3, Stephen Mallett4, Steven W Yancey2 and Michael E Wechsler5, 1Respiratory TAU & Flexible Discovery Unit, GSK, Philadelphia, PA, USA, Philadelphia, PA, 2Respiratory Therapeutic Area, GSK, Research Triangle Park, NC, USA, Research Triangle Park, NC, 3Research and Development, Immuno-Inflammation TAU, GSK, Stockley Park West, Uxbridge, Middlesex, UK, Uxbridge, United Kingdom, 4Research & Development, Statistics, GSK, Stockley Park West, Uxbridge, Middlesex, UK, Uxbridge, United Kingdom, 5Department of Medicine,, National Jewish Health, Denver, CO

    Background/Purpose: In a recent Phase III study (NCT02020889) in patients with Eosinophilic Granulomatosis with Polyangiitis (EGPA) the anti-interleukin-5 monoclonal antibody mepolizumab showed significant benefit when…

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