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Abstracts tagged "Biologic agents and psoriatic arthritis"

  • Abstract Number: 2555 • ACR/ARHP Annual Meeting 2018

    Ixekizumab Treatment Results in Rapid and Sustained Improvements in the Disease Activity Index for Psoriatic Arthritis (DAPSA) in Patients Naïve to Biologic Dmards or with Previous Inadequate Response to TNF Inhibitors

    Prashanth Sunkureddi1, Baojin Zhu2,3, Alexis Ogdie4, Aubrey Spraberry3, Jeffrey Lisse3, Chen-Yen Lin3 and David Shrom2, 1Rheumatology, Clear Lake Rheumatology Center, Nassau Bay, TX, 2LRL, Eli Lilly and Company, Indianapolis, IN, 3Eli Lilly and Company, Indianapolis, IN, 4University of Pennsylvania, Philadelphia, PA

    Background/Purpose: The DAPSA is a composite tool that assesses several domains of psoriatic arthritis (PsA) manifestations and was developed as a disease activity measure for…
  • Abstract Number: 2602 • ACR/ARHP Annual Meeting 2018

    Evolution of Patient Characteristics in the Era of Biological Treatment of Psoriatic Arthritis: 18-Year Belgian Experience from Leuven Spondyloarthritis Biologics Cohort (BioSPAR)

    Alla Ishchenko1, Rik Lories2 and Kurt de Vlam3, 1Rheumatology, KU Leuven, Skeletal Biology and Engineering Research Center & University Hospitals Leuven, Leuven, Belgium, 2Skeletal Biology and Engineering Research Center, KU Leuven, Leuven, Belgium, 3UZ Leuven, Leuven, Belgium

    Background/Purpose: Biologicals revolutionized the management of PsA. Since the introduction of the first TNF inhibitor (TNFi) in the early 2000s, therapeutic options for PsA are…
  • Abstract Number: 1564 • ACR/ARHP Annual Meeting 2017

    Treatment Patterns, Survival and Long-Term Effectiveness of Biological Agents in Psoriatic Arthritis Patients

    Marina Natalia Fornaro1, Fernando Dal Pra2, Emilce E Schneeberger2, Osvaldo Luis Cerda2, Margarita Landi2, María de los Angeles Correa3, Rodrigo Garcia Salinas4, Sebastian Magri5, Raul Sueldo6, María Julia Santa Cruz7, Emilio Buschiazzo8 and Gustavo Citera9, 1Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, buenos aires, Argentina, 2Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, Buenos Aires, Argentina, 3Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Buenos Aires, Argentina, 4Section of Rheumatology, Hospital Italiano de La Plata, Buenos Aires, Argentina, La Plata, Argentina, 5Section of Rheumatology, Hospital Italiano de La Plata, La Plata, Argentina, 6Section of Rheumatology, Hospital Angel Cruz Padilla, Tucumán, Argentina, 7Section of Rheumatology, Hospital General de Agudos Dr. Enrique Tornú, Buenos Aires, Argentina, 8Section of Rheumatology, Hospital Señor del Milagro, Salta, Argentina, Salta, Argentina, 9Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, Buenos Aires, Argentina

    Background/Purpose: The incorporation of biological disease modifying drugs (b-DMARD) has substantially improved the outcome of patients with Psoriatic Arthritis (PsA). Our aim was to evaluate…
  • Abstract Number: 4L • ACR/ARHP Annual Meeting 2016

    Efficacy and Safety Results of Guselkumab, an Anti-IL23 Monoclonal Antibody, in Patients with Active Psoriatic Arthritis over 24 Weeks: A Phase 2a, Randomized, Double-Blind, Placebo-Controlled Study

    Atul A. Deodhar1, Alice B Gottlieb2, Wolf-Henning Boehncke3, Bin Dong4, Yuhua Wang4, William Barchuk5, Xie Xu5 and Elizabeth C. Hsia4, 1Oregon Health & Science University, Portland, OR, 2Department of Dermatology, New York Medical College, Valhalla, NY, 3Department of Dermatology,, Geneva University Hospital, Geneva, Switzerland, 4Janssen Research & Development, LLC, Spring House, PA, 5Janssen Research & Development, LLC, San Diego, CA

    Background/Purpose: To evaluate the efficacy, safety, and tolerability of guselkumab (GUS), a fully human monoclonal antibody against the p19 subunit of IL-23, in patients (pts)…
  • Abstract Number: 1554 • ACR/ARHP Annual Meeting 2014

    Early and Sustained Modified Psarc Response in Psoriatic Arthritis Patients Treated with Ustekinumab:  Results from 2 Phase 3 Studies

    Iain B. McInnes1, Christopher T. Ritchlin2, Proton Rahman3, Lluís Puig Sanz4, Alice B. Gottlieb5, Shu Li6, Michael Song6, Bruce Randazzo6, Yuhua Wang6, Alan M. Mendelsohn7 and Arthur Kavanaugh8, 1University of Glasgow, Glasgow, United Kingdom, 2Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY, 3Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, 4Dermatology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, 5Tufts Medical Center, Boston, MA, 6Janssen Research & Development, LLC., Spring House, PA, 7Immunology, Janssen Research & Development, LLC., Spring House, PA, 8University of California San Diego, La Jolla, CA

    Background/Purpose: We have previously reported the efficacy and safety results of ustekinumab (UST), an IL-12/23 p40 inhibitor, in patients with active psoriatic arthritis (PsA) up…

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