Abstracts tagged "bioinformatics and biomarkers"

Abstract Number: 2864 • ACR/ARHP Annual Meeting 2016
Identifying Dysregulated and Co-Dysregulated Markers in Systemic Lupus Erythematosus Using Multi-Modal Biomarker Data from a Large Pre-Clinical Study
Yanhua Sarah Hu¹, S Bandyopadhyay¹, Julie Carman², Nataly Manjarrez-Orduño², Can Jiang¹, Suzanne Suchard², Laurence Menard², sium habte¹, selena kansal¹, vivek jayaswal³, Richard A. Furie⁴ and Steven G. Nadler⁵, ¹Bristol-Myers Squibb, Princeton, NJ, ²Discovery Translational Sciences Group, Bristol-Myers Squibb, Princeton, NJ, ³Biocon Bristol-Myers Squibb Research Center, Bangalore, NJ, India, ⁴Division of Rheumatology, North Shore LIJ Health System, Great Neck, NY, ⁵Immunosciences Translational Research, Bristol-Myers Squibb, Princeton, NJ
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic, relapsing autoimmune disease affecting multiple organs and is a highly heterogeneous condition, with wide variations in the…
Abstract Number: 788 • ACR/ARHP Annual Meeting 2015
Identification of Molecular Biomarkers to Distinguish Systemic Lupus Erythematosus with Skin Involvement from Discoid Lupus Erythematosus and Subacute Cutaneous Erythematosus: Provisional Results from Cross-Sectional Studies
Matteo Cesaroni¹, Jarrat Jordan¹, Jessica Schreiter¹, Marc Chevrier¹, Grace Wang², Cesar Calderon³, Alexa Piantone², Ian Gourley⁴, Stanley Cohen⁵, Scott Fretzin⁶, Anna Wozniacka⁷, Victoria P. Werth⁸ and Jacqueline Benson¹, ¹Estrela Lupus Venture, Janssen Research and Development, LLC., Spring House, PA, ²Janssen Research and Development, Spring House, PA, ³37 Derwen Dr., Janssen Research and Development, Havertown, PA, ⁴1329 Anthony Wayne drive, Janssen Research and Development, Wayne, PA, ⁵Metroplex Clinical Research Center, LLC, Dallas, TX, ⁶Dawes Fretzin Clinical Research Group, LLCC, Indianapolis, IN, ⁷Medical University of Lodz, Lodz, Poland, ⁸Philadelphia VA Medical Center, Philadelphia, PA
Background/Purpose: Sub-classification of Lupus Erythematosus (LE) patients is largely based on defined clinical criteria while biological factors associating with or contributing to these clinical features…