Abstracts tagged "bDMARDs"

Abstract Number: 1215 • ACR Convergence 2021
Development of a Multivariable Prediction Model for Treatment Response to Etanercept in a Multi-centre Cohort of Patients with Established RA
Michael Stadler¹, Stephanie Ling², Nisha Nair², John Isaacs³, Kimme Hyrich², Ann Morgan⁴, Anthony Wilson⁵, Darren Plant², Anne Barton² and John Bowes², ¹University of Manchester, Preston, United Kingdom, ²University of Manchester, Manchester, United Kingdom, ³Newcastle University, Newcastle upon Tyne, United Kingdom, ⁴University of Leeds, Leeds, United Kingdom, ⁵Center for Arthritis Research, Conway Institute, University College Dublin, Dublin, Ireland
Background/Purpose: RA patients who respond inadequately to first-line DMARDs usually progress to a biologic DMARD. Treatment response to both DMARDs and biologics is heterogeneous within…
Abstract Number: 1690 • ACR Convergence 2021
Safety and Efficacy of Long-term Sarilumab Treatment in Patients with Active Rheumatoid Arthritis: EXTEND and MONARCH Open Label Extension Studies
Gerd Burmester¹, Vibeke Strand², Alan Kivitz³, Chih-Chi Hu⁴, Sheldon Wang⁴, Hubert van Hoogstraten⁵, Ray Tao⁶ and Roy Fleischmann⁷, ¹Charité University Medicine Berlin, Berlin, Germany, ²Stanford University School of Medicine, Portola Valley, CA, ³Altoona Center for Clinical Research, Duncansville, PA, ⁴Sanofi Genzyme, Bridgewater, NJ, ⁵Sanofi, Bridgewater, NJ, ⁶Sanofi China R&D, Shanghai, China (People's Republic), ⁷Metroplex Clinical Research Center and University of Texas Southwestern Medical Center, Dallas, TX
Background/Purpose: In patients who experience intolerance or fail to respond to methotrexate, IL-6 receptor inhibitors (e.g. sarilumab) are one of the recommended options. The aim…

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