Abstracts tagged "BAFF and lymphocytes"

Abstract Number: 1756 • 2012 ACR/ARHP Annual Meeting
Peripheral Blood B Cell Subsets and BAFF/APRIL Receptor Expression, Together with Circulating BAFF and APRIL Levels, Are Disturbed in Rheumatoid Arthritis but Not in Ankylosing Spondylitis
Béatrice Gaugler¹, Caroline Laheurte², Ewa Bertolini³, Daniel Wendling⁴, Philippe Saas⁵, Eric Toussirot⁶ and CIC BT506⁷, ¹EFS Bourgogne Franche Comté, INSERM UMR1098 / Etablissement Français du Sang / Université de Franche Comté, Besançon, France, ²Etablissement Français du Sang/ Université de Franche Comté / CBT506 / CHRU, INSERM UMR1098 / Plateforme Biomonitoring, Besançon, France, ³University Hospital, Rheumatology, Besançon, France, ⁴Service de Rhumatologie, Minjoz University Hospital, Besancon, France, ⁵Etablisement Français du Sang ; Université de Franche Comté, INSERM UMR1098, Besançon, France, ⁶Université de Franche Comté , CHRU, CIC Biotherapy 506 and Rheumatology and EA 4266 Pathogens and Inflammation, Besançon, France, ⁷Chru, Clinical Investigation Center Biotherapy, Besançon, France
Background/Purpose: B cells play a critical role in systemic autoimmune disease and especially rheumatoid arthritis (RA). BAFF and APRIL are involved in B cell activation…

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