Abstract Number: 2873 • ACR/ARP Annual Meeting 2019
Antimicrobial Use Is High in Patients with Rheumatoid Arthritis, and Further Increases with First-Line TNFi Therapy – Nationwide Results from Iceland
Background/Purpose: Severe infections, frequently resulting in hospitalization, are a well-known adverse effects of tumor necrosis factor inhibitors (TNFi). However, studies regarding outpatient treated infections are…Abstract Number: 942 • ACR/ARHP Annual Meeting 2018
Risk of Serious Infections in Tocilizumab Versus TNF Inhibitor Initiators in Patients with RA: A Multi-Database Cohort Study
Background/Purpose: While biologics are known to be associated with risk of serious infections, data on head-to-head comparison of different biologic drugs for the risk of…Abstract Number: 1238 • ACR/ARHP Annual Meeting 2018
The Effect of Antibiotic Therapy on Positive Culture Results Among Patients with Prosthetic Joint Septic Arthritis
Background/Purpose: Little is known about the effects of antibiotic therapy on synovial and blood culture results among patients with prosthetic joint septic arthritis (PJSA). In…Abstract Number: 1239 • ACR/ARHP Annual Meeting 2018
Organisms Associated with Prosthetic Joint Septic Arthritis over the Past Two Decades: Data from a Single Tertiary Medical Center Located in the Northeastern United States
Background/Purpose: In recent years, joint replacement surgery (JRS) has become increasingly common. Prosthetic joint septic arthritis (PJSA) may complicate JRS in up to 1% of…Abstract Number: 1883 • ACR/ARHP Annual Meeting 2018
Infections Are Associated With Increased Risk of Giant Cell Arteritis – a Population-Based Case-Control Study From Southern Sweden
Background/Purpose: Previous studies have implicated infections as a risk factor for giant cell arteritis (GCA). The purpose of this study was to investigate the association…Abstract Number: 2453 • ACR/ARHP Annual Meeting 2018
Staphylococcus Aureus Carriage Rates Are High in Rheumatoid Arthritis Patients on Biologics
Background/Purpose: Patients with rheumatoid arthritis (RA) have a higher risk of surgical site infection than patients with osteoarthritis (OA). Disease modifying therapy is widely used…Abstract Number: 1317 • ACR/ARHP Annual Meeting 2016
Do Patients with MRSA-Positive Septic Arthritis Differ Clinically from Non-MRSA-Positive Counterparts?
Do patients with MRSA-positive septic arthritis differ clinically from non-MRSA-positive counterparts? Mary Louise Fowler3, Kevin Byrne3, Sarah B. Lieber1, Andrew Moore2, Robert H. Shmerling1, Ziv…Abstract Number: 1354 • ACR/ARHP Annual Meeting 2015
Whipple’s Disease: The Diagnostic Utility of Synovial Fluid Tropheryma Whipplei Polymerase Chain Reaction
Background/Purpose: Inflammatory arthritis is a common, non-specific symptom of Whipple’s disease. Recovery of the organism by conventional culture is often unsuccessful. Synovial fluid polymerase chain…Abstract Number: 2851 • ACR/ARHP Annual Meeting 2015
Anti-TNF Therapy Is Associated with an Increase in Serious Infections in Patients with Spondyloarthritis (SpA), Especially during the First 12 Monts of Treatment: Results from the GISEA Registry
Background/Purpose: Infection is by far the most common and most important adverse effect of TNF inhibitors (TNFI) in the treatment of rheumatoid arthritis (RA) and…Abstract Number: 2153 • ACR/ARHP Annual Meeting 2014
Clinical Characteristics and Outcomes in Synovial Fluid Culture ̵ Negative Septic Arthritis
Background/Purpose: Delays in diagnosis and treatment of septic arthritis may be associated with significant morbidity. While many patients with suspected or proven septic arthritis are…Abstract Number: 936 • ACR/ARHP Annual Meeting 2014
Active Invasion of Periodontal Bacteria into Synovial Joint Exacerbates Collagen-Induced Arthritis in Disease-Prone B10 Riii Mice
Background/Purpose: Periodontitis (PD) is a chronic immunoinflammatory disease caused by complex subgingival periodontal bacteria. Rheumatoid Arthritis (RA) and PD both are chronic inflammatory disorders characterized…Abstract Number: 2895 • ACR/ARHP Annual Meeting 2013
Bacterial Amyloids Promote Type I Interferon Production and Accelerate Autoimmunity
Background/Purpose: Infection is a major cause of morbidity and mortality in patients with systemic lupus erythematosus (SLE). This is largely due to the use of…Abstract Number: 1580 • ACR/ARHP Annual Meeting 2013
Drug-Resistant Bloodstream Infections In Systemic Lupus Erythematosus Patients: A Clinical Perspective
Background/Purpose: Infections are an important cause of mortality and morbidity in Systemic Lupus Erythematosus (SLE) patients. Different risk factors have been described for the development…Abstract Number: 2524 • ACR/ARHP Annual Meeting 2012
Snapin Is Critical for the Maturation of Autophagosome and Phagosome in Macrophages
Background/Purpose: We found that Snapin, a SNARE complex protein required for synaptic vesicle docking and fusion, was significantly increased in rheumatoid arthritis (RA) synovial tissue…Abstract Number: 1197 • ACR/ARHP Annual Meeting 2012
Porphyromonas Gingivalis and the Pathogenesis of Rheumatoid Arthritis: Analysis of the Synovial Tissue and of Other Compartments
Background/Purpose: Porphyromonas gingivalis (Pg), a periodontal anaerobic intracellular pathogen, has been recently associated to rheumatoid arthritis (RA) and the pathogenesis of the disease, due to…
ACR Meeting Abstracts